Clinical trials: in Rwanda
Oral Cancer, Health Education, Community
Testing and Comparing the Impacts of Mhealth-Based and Web-Based Education on Oral Cancer
Introduction: Oral cancer is a malignant neoplastic disease affecting the lip, oral cavity (mouth) and/or the oropharynx. Despite the intense and diverse public health interventions on oral cancer prevention, the global…
- Conditions
- Oral Cancer, Health Education, Community, Digital Intervention, MHealth Application
- Trial name
- NCT06711848
- Testing
- A web-based educational intervention on oral cancer, A mobile health app-based educational intervention on oral cancer
- Where
- 5 sites in India, Nigeria and 2 more
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
Rheumatic Heart Disease
RhEumatiC Heart diseAse Genetics
Rheumatic fever (RF) is an autoimmune disease that is mediated by the cellular and humoral immune response that follows an untreated pharyngeal Streptococcus pyogenes infection.
- Trial name
- RECHARGE (NCT02118818)
- Testing
- Next generation sequencing
- Where
- Rwanda
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Epilepsy
Risk Factors and Etiologies of Epilepsy in Urban and Rural Rwanda
Epilepsy is one of the most common chronic brain disorders. Up to 85% of persons living with epilepsy (PwE) live in the developing world. In sub-Saharan Africa (SSA), Rwanda has one of the highest prevalence rates (±5%).
- Trial name
- REpiCa (NCT05698537)
- Testing
- EEG, Neuroimaging, Blood sample
- Where
- Rwanda
- Volunteers
- 1,745 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Metabolic Syndrome, Nutritional Status
Dietary Practices and Metabolic Syndrome in the Young Adult Population of Rwanda
Policy makers in Rwanda have recently highlighted the importance of promoting healthy diets and lifestyle in response to rapidly increasing rates of obesity.
- Conditions
- Metabolic Syndrome, Nutritional Status, Diet Habit
- Trial name
- NutriTransit (NCT04204538)
- Testing
- Dietary habits, Risk factors associated with metabolic syndrome
- Where
- Rwanda
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- University Ghent
Mental Disorder
Validation of Instruments for Clinical Trial on Patients With Bipolar Disorder in Rwanda
This study evaluates the cultural and linguistic sensitivity and psychometric properties of a set of four adapted measurement instruments essential to determining the efficacy of group-psychoeducation for patients with bipolar…
- Trial name
- NCT04834999
- Testing
- Validation of questionnaires in Kinyarwanda
- Where
- Rwanda
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hiv, Aids
Reducing Time to Spaced-out Appointments for Newly-diagnosed People Living With HIV
The objectives of this study are to pilot test the effect of reducing time to spaced-out appointments from 18 to 6 months for newly-diagnosed people living with HIV (PLWH) in Rwanda who have initiated antiretroviral therapy…
- Trial name
- NCT04567693
- Testing
- Early spaced-out appointments
- Where
- Rwanda
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
HIV-1-infection
A Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644)
A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) in HIV-1 Uninfected Adults in Good General Health.
- Trial name
- NCT05414786
- Testing
- eOD-GT8 60mer mRNA Vaccine (100µg)
- Where
- 2 sites in Rwanda, South Africa
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
Malaria
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda
The use of insecticide-treated bed nets (ITNs) has contributed to the substantial reduction in malaria cases and deaths. This progress is threatened by increasing resistance in mosquito populations to commonly used insecticides.
- Trial name
- NCT04230161
- Testing
- Standard long-lasting insecticidal net, Chlorfenapyr insecticide treated net, Indoor residual spraying
- Where
- Rwanda
- Volunteers
- 3,502 people, healthy volunteers welcome
- Sponsor
- PATH
Global Health, Education
Can VAST Improve ACLS in Rwanda
Aim The purpose of this study is to determine if the addition of the VAST Course to technical resuscitation skills training enhances healthcare providers' resuscitation performance in a resource-limited setting.
- Conditions
- Global Health, Education, Resuscitation
- Trial name
- NCT05278884
- Testing
- Advanced Cardiac Life Support Training, Vital Anesthesia Simulation Training
- Where
- Rwanda
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gender-based Violence, Adherence
Impacts of Clean Cookstoves and Empowerment Training on Women's Health in Refugee Settings
The main objective of this study is to understand the links and outcomes of adoption of a cleaner cookstove/fuel and exposure to a personal empowerment training on women's health outcomes in a Congolese refugee camp in Rwanda…
- Conditions
- Gender-based Violence, Adherence, Mental Health Wellness 1, Empowerment
- Trial name
- NCT04081441
- Testing
- Inyenyeri clean cookstove and fuel system, I-ACT (Individual, Agency-Centered Training) workshop
- Where
- Rwanda
- Volunteers
- 1,555 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gender Relations, Partner Communication
Impact of COVID-19 on Family Dynamics on Bandebereho Study Participants
This proposed study will assess how COVID-19 and the associated 'stay at home' orders are affecting low-income Rwandan couples' relationships and family dynamics.
- Conditions
- Gender Relations, Partner Communication, Division of Carework, Couple Conflict
- Trial name
- NCT04442152
- Testing
- MenCare+/Bandebereho fathers'/couples' group education
- Where
- Rwanda
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- Promundo, United States
HIV Infections
Safety of and Immune Response to an Adenoviral HIV Vaccine (VRC-HIVADV014-00-VP) With or Without a Plasmid HIV Vaccine (VRC-HIVDNA016-00-VP) in HIV Uninfected Adults
The purpose of this study is to determine the safety of and immune response to an investigational HIV vaccine, VRC-HIVADV014-00-VP, with or without a second investigational HIV vaccine, VRC-HIVDNA016-00-VP, in HIV uninfected…
- Trial name
- NCT00124007
- Testing
- VRC-HIVADV014-00-VP, VRC-HIVDNA016-00-VP
- Where
- 3 sites in Kenya, Rwanda
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gender Relations, Violence
Bandebereho 6 Year Follow up RCT in Rwanda
This study seeks to conduct a six-year follow-up of the Bandebereho randomized control trial (RCT) to assess the longer-term impact of the gender-transformative Bandebereho couples intervention on participating men, women, and…
- Conditions
- Gender Relations, Violence, Child Development, Contraception
- Trial name
- NCT04861870
- Testing
- MenCare+/Bandebereho fathers'/couples' group education
- Where
- Rwanda
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Promundo, United States
Inadequate Child Growth
Enhancing Milk Consumption for Improved Nutrition in Rwanda
This study is a mixed-methods cluster-randomized controlled trial in Rwanda designed to measure the impact of a dairy asset transfer program with or without nutrition education promoting the home consumption of dairy milk and…
- Trial name
- NCT03455647
- Testing
- ASF promotion plus Girinka
- Where
- 2 sites in Rwanda
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- RTI International
To Determine the Change in Demonstrated Anesthesia Non-technical Skills After Delivery of the VAST Course
Can we Make a VAST Improvement? Promoting Anaesthetists' Non-technical Skills Through the Vital Anaesthesia Simulation Training Course in a Low-resource Setting
Rationale: The World Health Assembly resolution 68.15 identified surgical and anesthesia care as core components of universal health coverage.
- Trial name
- NCT04521101
- Testing
- VAST Course
- Where
- 2 sites in Rwanda
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Jaundice, Neonatal
Understanding Neonatal Jaundice in Rwanda
This study exploits the distribution of low-cost high-quality phototherapy devices (Brilliance by D-Rev) to public hospitals in Rwanda to assess whether the provision of improved technology improves health care for infant…
- Trial name
- NCT03184948
- Testing
- Brilliance
- Where
- Rwanda
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
HIV/AIDS and Infections, Electronic Medical Records
Evaluation of Clinical Impacts and Costs of eHealth in Rwanda
This study will estimate the impact of a suite of clinical decision-support tools on structural, process, and clinical outcomes related to HIV care.
- Conditions
- HIV/AIDS and Infections, Electronic Medical Records, Clinical Decision Support System
- Trial name
- NCT04283929
- Testing
- Experimental: Intervention 1 (Int1), Experimental: Intervention 2 (Int2), Experimental: Intervention 3 (Int3)
- Where
- Rwanda
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National University, Rwanda
Malaria in Pregnancy
Routine Antenatal Care Versus Screening and Treatment of Malaria in Pregnancy in Rwanda
The main aim of this study is to test the primary hypothesis that the addition of intermittent screening and treatment of malaria in pregnant women (ISTp) who receive routine antenatal care (ANC) in health facilities in high…
- Trial name
- NCT03508349
- Testing
- IST
- Where
- 14 sites in Rwanda
- Volunteers
- 1,786 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Sexually Transmitted Disease, Bacterial Vaginosis
Women's Improvement of Sexual Health (WISH) Demonstration Project
The current standard of care for urogenital infections in Rwanda is syndromic management. Many urogenital infections are asymptomatic and therefore completely missed, and the management of vaginal discharge syndrome is known to…
- Conditions
- Sexually Transmitted Disease, Bacterial Vaginosis, Vaginal Candidiasis, Urinary Tract Infections
- Trial name
- WISH (NCT03045809)
- Testing
- Urogenital infection point-of-care tests
- Where
- Rwanda
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Janneke van de Wijgert
Pregnancy Complications, Preterm Birth
Group Antenatal/Postnatal Care in Rwanda
The focus of this work is to improve antenatal care (ANC) and postnatal care (PNC) at the health center level in five districts in Rwanda (Bugesera, Burera, Nyamasheke, Nyarugenge, and Rubavu).
- Conditions
- Pregnancy Complications, Preterm Birth, Preterm Labor, Stillbirth
- Trial name
- PTBi Rwanda (NCT03154177)
- Testing
- Group ANC/PNC, Ultrasound+Pregnancy Testing
- Where
- 2 sites in Rwanda
- Volunteers
- 26,381 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco