Clinical trials: in Spain
Respiratory Syncytial Virus Infections
A Study on the Immune Response, Safety and the Occurrence of Respiratory Syncytial Virus (RSV)-Associated Respiratory Tract Illness After Administration of RSV OA Vaccine in Adults 60 Years and Older
The purpose of the current study is to evaluate the immune response of the RSVPreF3 OA investigational vaccine in older adults (OA) at least (>=) 60 years of age (YOA) in China compared to OA in the same age range to be enrolled…
- Trial name
- NCT06551181
- Testing
- RSVPreF3 OA investigational vaccine
- Where
- 40 sites in China, Finland and 5 more
- Volunteers
- 2,620 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cardiomyopathies, Cardiac Arrest
AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)
WILLEM is a multi-center, prospective and retrospective cohort study. The study will assess the performance of a cloud-based and AI-powered ECG analysis platform, named Willem™, developed to detect arrhythmias and other abnormal…
- Conditions
- Cardiomyopathies, Cardiac Arrest, Cardiac Arrhythmias, Sudden Cardiac Death
- Trial name
- WILLEM (NCT05890716)
- Testing
- AI-powered ECG analysis to detect cardiac arrhythmic episodes
- Where
- 13 sites in Netherlands, Spain
- Volunteers
- 5,342 people, healthy volunteers welcome
- Sponsor
- Idoven 1903 S.L.
Respiratory Syncytial Virus (RSV)
Study to Learn About a Respiratory Syncytial Virus Vaccine in Children at High Risk of RSV Disease
The purpose of the study is to evaluate the safety, tolerability, and immunogenicity of RSVpreF in children 5 to <18 years of age at high risk for RSV disease, including those who are immunocompromised.
- Trial name
- NCT07839871
- Testing
- RSVpreF
- Where
- 20 sites in United States, Japan and 2 more
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Pfizer
Meningitis
A Phase 3 Study to Assess the Immune Response and Safety of rMenB+OMV NZ in Primed Healthy Participants (10 to 20 Years Old)
The main purpose of this study was to evaluate the immune response and safety of a booster dose of the meningococcal group B vaccine, rMenB+OMV NZ (also known as Bexsero), in adolescents and young adults aged 10 to 20 years.
- Trial name
- NCT06995430
- Testing
- rMenB+OMV NZ vaccine
- Where
- 17 sites in Finland, Italy and 2 more
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pneumococcal Disease
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
The purpose of this study is to learn about the safety of a new pneumococcal vaccine and how the new pneumococcal vaccine helps to fight against germs that can cause pneumonia (lung infections), meningitis (brain infections), and…
- Trial name
- NCT07573462
- Testing
- PG4, 20-valent pneumococcal conjugate vaccine (20vPnC)
- Where
- 91 sites in United States, Argentina and 9 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Pfizer
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Artificial Intelligence Mobile Application
Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition.
This study aims to improve how we understand and manage blood sugar responses in adults without diabetes. Even in people who appear healthy, blood sugar levels after meals can behave in different ways.
- Trial name
- Food_i Sense (NCT07626658)
- Testing
- Continuous glucose monitoring using a wearable sensor (flash interstitial glucose monitor)
- Where
- Spain
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Musculoskeletal Discomfort, Foot Discomfort
Comparing Foot-Type-Matched and Neutral Insoles for Foot Discomfort in Factory Workers
The goal of this clinical trial was to learn whether prefabricated insoles chosen according to a worker's foot type reduce foot discomfort more than neutral prefabricated insoles in assembly-line workers who stand for most of…
- Conditions
- Musculoskeletal Discomfort, Foot Discomfort, Occupational Health
- Trial name
- NCT07920523
- Testing
- Foot-type-matched prefabricated insole, Neutral prefabricated insole
- Where
- Spain
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Muscle Fatigue, Healthy Adult
Recovery After Fatigue in Young Athletes: Comparison Between TECAR Therapy and Cycle Ergometer"
The goal of this clinical trial is to compare two recovery methods after fatigue in young athletes. It aims to find out if tecar therapy (TECAR) or cycle ergometer exercise can improve recovery after intense physical activity and…
- Trial name
- NCT07547566
- Testing
- Tecar therapy (capacitive mode), Active recovery using cycle ergometer
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Infertility Due to Nonimplantation
Impact of Endometrial Compaction on Reproductive Outcomes After Cryotransfer of Euploid Embryos in a Natural Cycle
Multicenter prospective observational cohort study, comparing ongoing pregnancy rates in natural cycles for euploid embryo transfer in patients who present endometrial compaction at the time of the transfer versus those who have…
- Trial name
- Compaction (NCT05960370)
- Testing
- Observational non intervention study
- Where
- Spain
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Post Menopausal Women
The Role of Diet Quality in Sleep Among Women in Postmenopause
This single-center, randomized controlled trial with parallel groups, consists of an intensive nutritional intervention based on a high-fiber Mediterranean diet (target intake: 30-35 g/day of dietary fiber), which will be…
- Trial name
- EMILE (NCT07918287)
- Testing
- Intensive High-Fiber Mediterranean Diet Counseling, Low-Intensity Mediterranean Diet Counseling
- Where
- Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Alzheimer's Dementia (AD), Alzheimer Disease (AD)
Exercise in Alzheimer's Disease: Functional Biomarkers
Alzheimer's disease (AD) is the leading cause of dementia worldwide and involves systemic alterations beyond the brain, such as loss of muscle strength, chronic low-grade inflammation, and gut microbiome dysbiosis.
- Trial name
- AD-GUT-EX (NCT07918417)
- Testing
- High load, Moderate load, Healthy adults - High load
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Sleep Apnea, Obstructive
Obstructive Sleep Apnea and Biomarkers of Alzheimer's Disease
Clinical trial on the effect of continuous positive pressure (CPAP). Objectives: 1) To compare biomarkers of Alzheimer's disease in plasma samples from patients with Obstructive sleep apnea (OSA) and without OSA.
- Trial name
- NCT04905238
- Testing
- Continuous positive airway pressure
- Where
- 2 sites in Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Alberto Alonso Fernandez
Anorexia Nervosa Restricting Type, Anorexia Nervosa (DSM-IV Revised Criteria)
Biomarkers in EV Associated With Marrow Adiposity in Anorexia
The aim of this observational study is to identify biomarkers in extracellular vesicles associated with medullary adiposity occurring in patients with anorexia nervosa.
- Trial name
- VE_BMAT_AN (NCT06712485)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Neurologic Disorders
Advanced Multisensorial System for Automatic Assessment of Neurological Disorders in Smart Spaces-Universidad Rey Juan Carlos (URJC)
Neurological diseases affect people's cognitive and physical abilities, limiting their functional independence and causing disability, which in many cases, is progressive and degenerative.
- Trial name
- NeurEYE-URJC (NCT07909824)
- Testing
- NeurEYE: healthy people, NeurEYE: people with neurological diseases
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Cardiopulmonary Resuscitation, Out-of-Hospital Cardiac Arrest
Compression-Only Versus Standard Basic Life Support Training in Nursing Students
Survival after out-of-hospital cardiac arrest rarely exceeds 10%, and cardiopulmonary resuscitation (CPR) started by bystanders is a key factor for survival.
- Trial name
- NCT07915778
- Testing
- BLS and AED Training With Rescue Breaths, BLS and AED Training Without Rescue Breaths
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Eating Disorders, Body Image Dissatisfaction
Development, Implementation, and Evaluation of the HADAS Program for the Prevention of Eating Disorders in Adolescent Female Athletes, Coaches, and Families.
Adolescent female athletes in aesthetic sports disciplines (such as rhythmic gymnastics, artistic gymnastics, synchronized swimming, and figure skating) face a complex interaction between general sociocultural beauty pressures…
- Trial name
- The HADAS (NCT07750301)
- Testing
- The HADAS Program
- Where
- Spain
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section With Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Nitrate, Placebo - Control
Beetroot Juice and Neuromuscular Performance in Female Basketball Players
A randomized, double-blind, placebo-controlled study investigates the effects of 5 days of nitrate-rich beetroot juice supplementation (70 mL·day-¹; 6.4 mmol NO₃-·day-¹) on physical performance in female basketball players.
- Trial name
- BASKET_BEET (NCT07833579)
- Testing
- Beetroot juice supplementation
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Myotonic Dystrophy 1, DM1
The Spanish National Registry for Myotonic Dystrophy Type 1
Myotonic Dystrophy Type 1 (DM1) is a rare genetic neuromuscular condition that can affect multiple organs and varies widely in how it presents.
- Conditions
- Myotonic Dystrophy 1, DM1, Myotonic Dystrophy Type 1, Myotonic Dystrophy, Congenital
- Trial name
- DM1-Hub (NCT07385443)
- Testing
- Patient Registry
- Where
- 8 sites in Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Dental Pain, Inferior Alveolar Nerve Block Failure, Local Anesthesia
- Trial name
- NCT07130760
- Testing
- Intraligamentary Injection, Inferior Alveolar Nerve Block
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aula Dental Avanzada
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