Clinical trials: in Yemen
Preeclampsia
Vitamin D3 Supplementation Regimens and Preeclampsia Risk
This study is a randomized controlled trial with two parallel groups connected at Al-Thawra Modern General Hospital in Sana'a, Yemen.
- Trial name
- VitD-PE-RCT (NCT07648706)
- Testing
- Vitamin D3
- Where
- Yemen
- Volunteers
- 268 people
- Sponsor
- Sana'a University
Sellar Mass, Pituitray Tumor
Sellar Masses: Clinical and Imaging Features With Correlation to Histopathology and Surgical Approach
The goal of this observational study is to learn about the clinical spectrum of sellar masses, aiming to understand the correlation between the imaging features and the future surgical approach and histopathology results.
- Trial name
- NCT07633860
- Testing
- Craniectomy
- Where
- Yemen
- Volunteers
- 49 people
- Sponsor
- Arab Board of Neurosurgery
Kidney Calculi, Nephrolithiasis
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
The goal of this clinical trial is to compare the safety, cost-effectiveness, and patient recovery of two different surgical positions for percutaneous nephrolithotomy (PCNL) in adults aged 18 to 70 years who have kidney stones…
- Trial name
- NCT07627503
- Testing
- Supine Percutaneous Nephrolithotomy (PCNL), Prone Percutaneous Nephrolithotomy (PCNL)
- Where
- Yemen
- Volunteers
- 140 people
- Sponsor
- Sana'a University
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Infertility Drugs, Infertility Involuntary
Letrozole vs. Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes.
Infertility is a common reproductive health problem. Ovulation induction is a key treatment for women with anovulatory infertility. Letrozole and clomiphene citrate are widely used medications for ovulation induction.
- Trial name
- LET-CC-TAM (NCT07616973)
- Testing
- Letrozole, Clomiphene Citrate + Tamoxifen
- Where
- Yemen
- Volunteers
- 240 people
- Sponsor
- Sana'a University
Skeletal Class II Malocclusion
"Sliding Jigs vs Retraction Hooks for Maxillary Dentition Distalization Using IZC Miniscrews"
This randomized controlled clinical trial aims to compare the clinical efficacy, efficiency, and biomechanical differences between two methods for total maxillary dentition distalization: (1) the use of a Sliding Jig and (2) the…
- Trial name
- SJRH-IZC (NCT07307209)
- Testing
- Sliding jig, retraction hooks
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Periodontal Disease
Efficacy of Laser Therapy for Periodontitis
The aim of this study is to evaluate the efficacy of diode laser in addition to periodontal treatment in periodontitis patients and to investigate their effects on gingival crevicular fluid (GCF) cytokine levels before and after…
- Trial name
- NCT07013162
- Testing
- High power diode laser + SRT, Low diode diode laser + SRT, Curettage (SRT) only
- Where
- 2 sites in Yemen
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Wisdom Tooth Removal, Post Operative Complications
Comparing Methylprednisolone And Hyaluronic Acid To Reduce Wisdom Tooth Surgery Complications
The goal of this clinical trial is to assess and compare the effectiveness of methylprednisolone and hyaluronic acid (HA), alone and in combination, in managing post-operative complications following the surgical extraction of…
- Conditions
- Wisdom Tooth Removal, Post Operative Complications, Hyaluronic Acid, Methylprednisolone
- Trial name
- NCT07317596
- Testing
- Methyl Prednisolone (MP), Hyaluronic Acid (HA)
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Odontogenic Cyst, Jaw Cysts
Bone Regeneration Using PRF After Cyst Enucleation
This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws.
- Conditions
- Odontogenic Cyst, Jaw Cysts, Osseous Defect After Cyst Enucleation
- Trial name
- PRF-Bone (NCT07424716)
- Testing
- Autologous Platelet-Rich Fibrin (PRF), Conventional Surgical Management
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Accelerate Tooth Movement
Effect of Injectable Platelet Rich Derivatives on Orthodontic Canine Retraction
This study evaluated the effect of injectable platelet-rich derivatives on the rate of orthodontic canine retraction. Patients requiring orthodontic canine retraction following premolar extraction were enrolled and divided into…
- Trial name
- NCT07408895
- Testing
- Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF)
- Where
- Yemen
- Volunteers
- 21 people
- Sponsor
- Sana'a University
Orthodontic Treatment, Malocclusion
Intra-oral Evaluation of Force Decay of Pigmented and Transparent Elastomeric Power Chains:
This study aimed to evaluate the amount of force decay in pigmented and transparent elastomeric power chains. The principal investigator measured the amount of force decay at 7 intervals using a calibrated Dentaurum force gauge.
- Trial name
- NCT07300371
- Testing
- Matt gray elastomeric power chains, Matt blue elastomeric power chains, Matt pink elastomeric power chains
- Where
- Yemen
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction
Autogenous Tooth Bone Graft for Alveolar Socket Preservation
The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction.
- Conditions
- Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction, Tooth Extraction Site Healing
- Trial name
- ATBG (NCT07267637)
- Testing
- "Autogenous Tooth Bone Graft"
- Where
- Yemen
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haifaa Mohammed Al-hussini
Postoperative Atrial Fibrillation, Cardiac Tamponade
Posterior Pericardiotomy for Prevention of POAF After Cardiac Surgery: RCT in Yemen
A single-center, randomized controlled trial in Yemen evaluating whether posterior pericardiotomy (PP) reduces postoperative atrial fibrillation (POAF) after open-heart surgery.
- Trial name
- PP-POAF (NCT07266935)
- Testing
- Posterior Pericardiotomy, Standard Care
- Where
- Yemen
- Volunteers
- 210 people
- Sponsor
- Taiz University - Faculty of Medicine
Alveolar Bone Atrophy
Comparative (Short vs. Standard) Length Implants in Early Stability Patterns.
Early Stability of Short vs. Standard Dental Implants in the Posterior Mandible This study compares how well short dental implants (7mm) work compared to standard-length implants (11mm) when placed in the back part of the lower…
- Trial name
- NCT07162389
- Testing
- Shallow-Threaded Short Implant (SHI), Shallow-Threaded Standard Implant (SDI)
- Where
- Yemen
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Elastic Chains, Elastics
Effectiveness of Elastic Chains Versus Elastics in Maxillary Canine Retraction
This clinical study aimed to evaluate the effectiveness of Elastics and Elastic chains in maxillary canine retraction. Participants of this study were patients undergoing maxillary canine retraction after first premolar…
- Trial name
- CREST (NCT07141836)
- Testing
- Elastomeric chain, Elastics
- Where
- Yemen
- Volunteers
- 33 people
- Sponsor
- Sana'a University
Surgical Site Infection, Groin Hernia
Prophylactic Antibiotics in Groin Hernioplasty
The role of prophylactic antibiotics in preventing surgical site infections (SSI) for clean procedures like groin hernia repair remains controversial.
- Conditions
- Surgical Site Infection, Groin Hernia, Hernioplasty
- Trial name
- NCT07111702
- Testing
- Cefazolin
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Sever Mandibular Bone Resorption, Sensory Defect
Inferior Alveolar Nerve Translocation With Dental Implant Placement in Severely Resorbed Mandibles
This study investigates the effects of inferior alveolar nerve lateralization on the post-implant insertion sensory outcome for patients with severe mandibular bone resorption.
- Conditions
- Sever Mandibular Bone Resorption, Sensory Defect, Implant Failure
- Trial name
- NCT07104994
- Testing
- Dental implant
- Where
- Yemen
- Volunteers
- 9 people
- Sponsor
- University of Science and Technology, Yemen
Acute Cholecystitis
Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
The goal of this clinical trial is to learn if performing gallbladder surgery early is as safe and effective as delaying it for people with acute cholecystitis (a sudden gallbladder infection).
- Trial name
- EDLC-AC (NCT07101315)
- Testing
- Laparoscopic Cholecystectomy
- Where
- 2 sites in Yemen
- Volunteers
- 81 people
- Sponsor
- Sana'a University