Clinical trials: in Yemen
Mandibular Fractures
Z-Shaped Versus Conventional Miniplates for Mandibular Fractures
This study compares two different methods of repairing fractures at the front of the lower jaw (the symphysis and parasymphysis).
- Trial name
- NCT07901686
- Testing
- Z-shaped titanium miniplate, Conventional titanium miniplates
- Where
- 2 sites in Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Partial Edentulism Class 3, Removable Partial Denture
Clinical Fit of Conventionally Cast and 0° SLM Removable Partial Denture Frameworks
This exploratory pilot clinical study evaluates the fit accuracy of cobalt-chromium removable partial denture (RPD) frameworks fabricated using conventional lost-wax casting and selective laser melting (SLM) at a 0° build…
- Trial name
- NCT07863427
- Testing
- Conventionally Cast Cobalt-Chromium RPD Framework, 0° Selective Laser-Melted Cobalt-Chromium RPD Framework
- Where
- Yemen
- Volunteers
- 2 people
- Sponsor
- IBB University
Thin Gingival Phenotype
Injectable Platelet-Rich Fibrin and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.
This randomized split-mouth clinical trial will evaluate whether adding locally injected vitamin C to injectable platelet-rich fibrin (i-PRF) and microneedling improves gingival tissue thickness and keratinized tissue width in…
- Trial name
- NCT07848035
- Testing
- Microneedling, Injectable Platelet-Rich Fibrin (i-PRF), Vitamin C
- Where
- Yemen
- Volunteers
- 27 people
- Sponsor
- University of Science and Technology, Yemen
Facial Injuries, Pain
Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries
This randomized, controlled clinical trial will evaluate the clinical effects of a topical thermoresponsive hydrogel containing dexamethasone sodium phosphate and diclofenac sodium on postoperative pain and facial swelling in…
- Conditions
- Facial Injuries, Pain, Swelling
- Trial name
- NCT07853664
- Testing
- Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac
- Where
- Yemen
- Volunteers
- 52 people
- Sponsor
- Thamar University
Cross Bite
Evaluation of Myobrace for Crossbite Correction in Mixed Dentition
This randomized controlled clinical trial will evaluate the effectiveness of the Myobrace appliance in correcting anterior and posterior crossbite in children aged 6 to 10 years during the mixed dentition stage.
- Trial name
- Myo vs Frankel (NCT07840053)
- Testing
- Myobrace Interceptive Class III Appliance, Frankel III Functional Regulator
- Where
- Yemen
- Volunteers
- 40 people
- Sponsor
- Sana'a University
Gingival Inflammation
Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical Trial
Study Protocol Introduction Title of the research study Comparison Between the effect of Triclosan Toothpaste and chlorhexidine Mouthwash on Gingival Health in Fixed Orthodontic Patients :A randomization controlled clinical…
- Trial name
- NCT07814898
- Testing
- Triclosan 0.3% toothpaste, sodium fluoride 0.24% toothpaste, Chlorhexidine 0.2% mouthwash
- Where
- Yemen
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Patient Transport, Respiratory Failure
HERMES: International Survey and Portable External Power Evaluation During Respiratory Support Transport
The HERMES Phase I-II study was a two-phase observational investigation designed to characterize contemporary practices and safety-related challenges associated with the transport of patients requiring advanced respiratory…
- Conditions
- Patient Transport, Respiratory Failure, Noninvasive Ventilation, High-Flow Nasal Oxygen
- Trial name
- HERMES (NCT07807189)
- Testing
- Portable External Power Supply
- Where
- 20 sites in United States, Chile and 12 more
- Volunteers
- 246 people
- Sponsor
- Medipol University
Partial Edentulism, Dental Implant Placement
Effect of Advanced PRF and Hyaluronic Acid on Dental Implant Healing
This randomized parallel-group clinical trial aimed to evaluate the clinical efficacy of advanced platelet-rich fibrin (A-PRF) combined with hyaluronic acid (HA) in enhancing peri-implant bone formation in patients undergoing…
- Trial name
- NCT07792720
- Testing
- Delayed Dental Implant Placement, Advanced Platelet-Rich Fibrin (A-PRF), Hyaluronic Acid 1.5%
- Where
- Yemen
- Volunteers
- 30 people
- Sponsor
- Samar Ali Abdu Salamah
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Oromandibular Dystonia, Electromyography
Botulinum Toxin A for Jaw Dystonia .
This study evaluates the effectiveness and safety of Electromyography (EMG)-guided Botulinum Toxin type A (BTX-A) injections in treating oromandibular dystonia (OMD) among a sample of Yemeni patients.
- Trial name
- OMD _ BTX-A (NCT07792798)
- Testing
- Botulinum Toxin Type A (BOTOX) Injection
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Color Stability of Dental Ceramics, Zirconia Restorations
Impact of Khat Chewing on Color Stability and Patient Satisfaction of Multilayer Zirconia and Feldspathic Veneer Zirconia.
This study aims to evaluate and compare the impact of khat chewing on the color stability and patient satisfaction of multilayer zirconia and feldspathic veneered zirconia restorations.
- Conditions
- Color Stability of Dental Ceramics, Zirconia Restorations, Khat Chewing Effects, Dental Restoration Staining
- Trial name
- NCT07786272
- Testing
- Multilayer Zirconia Crowns, Feldspathic Veneered Zirconia Crowns
- Where
- Yemen
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thamar University
Osseodensification, Bone Expansion
Osseodensification for Narrow Alveolar Ridge Expansion
This prospective, single-arm, non-randomized interventional clinical study was designed to evaluate the immediate horizontal dimensional change in narrow alveolar ridges following osseodensification-assisted dental implant-site…
- Conditions
- Osseodensification, Bone Expansion, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- OD-RridgeExp (NCT07436533)
- Testing
- Densah burs (Osseodensification Technique)
- Where
- Yemen
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Cleft Palate, Unilateral Cleft Palate
Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty.
- Conditions
- Cleft Palate, Unilateral Cleft Palate, Bilateral Cleft Palate, Complete Cleft Palat
- Trial name
- NCT07752849
- Testing
- Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF
- Where
- Yemen
- Volunteers
- 90 people
- Sponsor
- Al-Thawra Modern General Hospital
Maxillofacial Trauma
Early Versus Late Intervention in Maxillofacial Trauma
Maxillofacial trauma represents a significant clinical challenge requiring timely surgical management. This prospective study aims to compare early versus delayed intervention in patients with maxillofacial trauma and evaluate…
- Trial name
- NCT07749729
- Testing
- Timing of Open Reduction and Internal Fixation (ORIF)
- Where
- 2 sites in Yemen
- Volunteers
- 50 people
- Sponsor
- Haifa Mohammed Sharaf-Aldeen
Carpal Tunnel Syndrome (CTS)
Comparative Efficacy of Therapeutic Ultrasound and Neurodynamic Techniques for Carpal Tunnel Syndrome
This randomized controlled trial compares the efficacy of therapeutic ultrasound alone, neurodynamic techniques alone, and combined therapeutic ultrasound and neurodynamic techniques in patients with mild to moderate carpal…
- Trial name
- NCT07743879
- Testing
- Neurodynamic Techniques
- Where
- Yemen
- Volunteers
- 60 people
- Sponsor
- IBB University
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Preeclampsia
Vitamin D3 Supplementation Regimens and Preeclampsia Risk
This study is a randomized controlled trial with two parallel groups connected at Al-Thawra Modern General Hospital in Sana'a, Yemen.
- Trial name
- VitD-PE-RCT (NCT07648706)
- Testing
- Vitamin D3
- Where
- Yemen
- Volunteers
- 268 people
- Sponsor
- Sana'a University
Sellar Mass, Pituitray Tumor
Sellar Masses: Clinical and Imaging Features With Correlation to Histopathology and Surgical Approach
The goal of this observational study is to learn about the clinical spectrum of sellar masses, aiming to understand the correlation between the imaging features and the future surgical approach and histopathology results.
- Trial name
- NCT07633860
- Testing
- Craniectomy
- Where
- Yemen
- Volunteers
- 49 people
- Sponsor
- Arab Board of Neurosurgery