Clinical trials: Lidocaine
Dental Anesthesia Efficacy
Safety and Effectiveness of Kovacaine Nasal Spray for Dental Anesthesia
The purpose of this study was to determine the safety and efficacy of Kovacaine Mist (3% tetracaine HCl with 0.05% oxymetazoline HCl) for anesthesia of the maxillary teeth for dental procedures.
- Trial name
- NCT01302483
- Testing
- 3% tetracaine HCL with 0.05% oxymetazoline HCL, Lidocaine Injection
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Renatus, LLC
Chronic Interstitial Cystitis
A Safety, Tolerability and Preliminary Efficacy Study of LiRIS® 400 mg in Women With Interstitial Cystitis (IC) and Hunner's Lesions
The purpose of the study is to evaluate if LiRIS 400 mg is safe and tolerable when administered to women with Interstitial Cystitis with Hunner's lesions, and to evaluate any change in the bladder or in IC symptoms, following…
- Trial name
- NCT01879683
- Testing
- LiRIS® 400 mg
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Allergan
Nasolabial Folds
Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections
Pliaglis® Cream versus compounded topical anesthetic for pain management during Restylane® injections for the correction of nasolabial folds.
- Trial name
- NCT00716443
- Testing
- tetracaine 7% / lidocaine 7% cream (Pliaglis® Cream), benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Galderma R&D
Nasolabial Fold, Hypoplastic
Princess® VOLUME Lidocaine for the Correction of Nasolabial Folds
In this study, eligible subjects with moderate to severe nasolabial folds will be treated with Princess® VOLUME Lidocaine and will return for follow-up assessments 2, 4, 24 and 36 weeks after the treatment.
- Trial name
- VINO (NCT03050710)
- Testing
- Princess® VOLUME Lidocaine
- Where
- 3 sites in Austria
- Volunteers
- 62 people
- Sponsor
- Croma-Pharma GmbH
Interstitial Cystitis, Bladder Pain Syndrome
Engage 24: Evaluation of the Safety and Effectiveness of URG101 in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to determine if the combination product (URG101) is safe and effective versus its individual components (Heparin Sodium and Lidocaine Hydrochloride) for the treatment of Interstitial Cystitis/Bladder…
- Trial name
- NCT02591199
- Testing
- URG101, Lidocaine, Heparin
- Where
- 11 sites in United States
- Volunteers
- 91 people
- Sponsor
- Urigen
Postherpetic Neuralgia
Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia
The purpose of this study is to determine whether KAI-1678 is effective in the treatment of postherpetic neuralgia pain
- Trial name
- NCT01106716
- Testing
- KAI-1678, Lidocaine
- Where
- Australia
- Volunteers
- 23 people
- Sponsor
- KAI Pharmaceuticals
Intravenous Placement Procedure
Satisfaction With Pediatric Intravenous Catheter Placement in the Emergency Department
The purpose of this study is to determine the satisfaction among parents and nurses of pediatric patients with IV catheter placement in the Emergency Department.
- Trial name
- NCT00766181
- Testing
- Zingo TM (lidocaine hydrochloride monohydrate) powder intradermal injection system
- Volunteers
- 200 people
- Sponsor
- Anesiva, Inc.
Volume Deficit in the Hand
Effectiveness and Safety of Restylane Lyft With Lidocaine in the Dorsal Hand
This is a randomized, evaluator-blind, split hand, multi-center study of the effectiveness and safety or Restylane Lyft with Lidocaine compared to no treatment for injection in the dorsal hand to correct volume deficits.
- Trial name
- NCT02650921
- Testing
- Restylane Lyft with Lidocaine
- Where
- 7 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Nasolabial Fold
Pain and Safety of Restylane Perlane With and Without Lidocaine for Correction of Moderate and Severe Nasolabial Folds
The purpose of this study is to evaluate the pain and safety in associated with injection of Restylane Perlane Lidocaine compared to Restylane Perlane using VAS scale
- Trial name
- NCT03174132
- Testing
- Restylane Perlane Lidocaine, Restylane Perlane
- Where
- 3 sites in Taiwan
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Nasolabial Folds
Neuramis® Deep Lidocaine Compared to YVOIRE® Volume Plus for Correction of Nasolabial Folds
This clinical investigation is a randomized, evaluator-blind, active controlled, noninferiority study to evaluate the effectiveness and safety of Neuramis® Deep Lidocaine when compared with YVOIRE® Volume Plus.
- Trial name
- NCT03753152
- Testing
- experimental, comparator
- Where
- China
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Medy-Tox
Healthy Volunteers
Study of the Tolerability of Ketorolac Tromethamine Following Intranasal Administration in Healthy Volunteers
This was a Phase 1, double blind, two part study in healthy male and female volunteers. Each subject participated in only one part of the study.
- Trial name
- NCT01363063
- Testing
- Ketorolac tromethamine
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Egalet Ltd
Ankle Sprains
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains
A Randomized, Multi-Center, Double-Blind, Factorial, Comparator and Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle…
- Trial name
- NCT01198834
- Testing
- MRX-7EAT, Lidocaine, Etodolac
- Where
- 33 sites in United States
- Volunteers
- 600 people
- Sponsor
- MEDRx USA, Inc.
Hip Pain Etiology Unknown
Navigator vs Standard Needle Injection for Hip
The purpose of this randomized, parallel-group, single-blinded, single center, Phase II study is to collect data to compare the comfort and patient satisfaction of a hip injection delivered via the Navigator compared to a…
- Trial name
- NCT02066844
- Testing
- Celestone, Lidocaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cartiva, Inc.
Lip Augmentation
Safety and Effectiveness of PN40082 for Lip Augmentation
To compare the safety and efficacy profile of PN40082 versus Restylane Silk Injectable Gel with 0.3% lidocaine (Restylane Silk) for lip augmentation in approximately 158 subjects.
- Trial name
- NCT04032977
- Testing
- PN40082, Restylane Silk
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Prollenium Medical Technologies Inc.
Lip Enhancement
Safety and Effectiveness of JUVÉDERM® VOLBELLA® With Lidocaine for Lip Enhancement in Chinese Adults
This study will evaluate the safety and effectiveness of VOLBELLA with Lidocaine injectable gel in Chinese adults seeking lip enhancement.
- Trial name
- NCT03519204
- Testing
- JUVÉDERM® VOLBELLA® XC with Lidocaine, No-treatment Control
- Where
- 5 sites in China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Allergan
Barotrauma;Ear, OME - Otitis Media With Effusion
Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
A prospective, multicenter study to evaluate effectiveness and safety of Tymbion iontophoresis and tympanostomy tube placement using the Tula iontophoresis and tube delivery systems for adults in an office setting.
- Conditions
- Barotrauma;Ear, OME - Otitis Media With Effusion, AOM - Acute Otitis Media, Eustachian Tube Dysfunction
- Trial name
- ADEPT (NCT03197558)
- Testing
- Tymbion Iontophoresis and Tube Delivery System (TDS)
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tusker Medical
Temple Hollowing
JUVÉDERM® VOLUMA® With Lidocaine for Correction of Temple Hollowing in Chinese Population
The objectives of this study are to evaluate the safety and effectiveness of JUVÉDERM® VOLUMA® with Lidocaine injectable gel in adult Chinese population seeking correction of temple hollowing.
- Trial name
- NCT04891419
- Testing
- JUVÉDERM® VOLUMA® with Lidocaine
- Where
- 8 sites in China
- Volunteers
- 168 people
- Sponsor
- Allergan
Myofascial Pain Syndromes
Study Evaluating Heated Lidocaine/Tetracaine Patch in Patients With Pain Associated With Myofascial Trigger Points
The purpose of this pilot study is to explore the potential usefulness of a heated lidocaine 70 mg and tetracaine 70 mg topical patch for the treatment of pain associated with myofascial trigger points.
- Trial name
- NCT01106989
- Testing
- Heated lidocaine/tetracaine patch
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ZARS Pharma Inc.
Mid Face Volume Deficit
THIODERM STRONG Compared to Juvéderm® VOLUMA® Lidocaine for the Treatment of Midface Volume Deficit
This mono-center clinical investigation is intended to evaluate the safety and effectiveness of THIODERM STRONG (test device) in the correction of moderate to severe midface volume deficit compared to Juvéderm® VOLUMA® Lidocaine…
- Trial name
- TIMI (NCT06128109)
- Testing
- Thioderm Strong, Juvéderm VOLUMA Lidocaine
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Croma-Pharma GmbH
Nasolabial Fold
Pain and Safety of Restylane With and Without Lidocaine for Correction of Moderate and Severe Nasolabial Folds
The purpose of this study is to evaluate the pain and safety associated with injections of Restylane Lidocaine compared to Restylane using a visual analogue scale.
- Trial name
- NCT02918721
- Testing
- Restylane Lidocaine, Restylane
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Galderma R&D