Clinical trials: Best Practice
Pulmonary Embolism
US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism
The objective of the study is to evaluate the safety and efficacy of the Adient absorbable filter for the prevention of pulmonary embolism (PE: blood clot in the lungs).
- Trial name
- NCT05127915
- Testing
- Adient absorbable filter + best practice VTE prophylaxis, best practice VTE prophylaxis
- Where
- 2 sites in United States
- Volunteers
- 854 people, healthy volunteers welcome
- Sponsor
- Adient Medical
HIV Seropositivity
A Multilevel, Multiphase Optimization Strategy for PrEP (MOST:PrEP)
What is known: There are 1.2 million people in the US who meet the indications for PrEP; yet, disparities exist in uptake. For example, only 9% of Black and 16% of Latino individuals, compared to 65% of White individuals, have…
- Trial name
- MOST:PrEP (NCT06334341)
- Testing
- Computer-based simulation training for providers, Best Practice Alert, HIV Risk Assessment
- Where
- United States
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Chronic Spine Pain, Fibromyalgia
Resilience Skills Self-Management for Chronic Pain.
The investigators will conduct a randomized controlled trial of an 8-week resilience-enhanced CBT online self-management program for chronic pain plus usual care (PRISM), standard e-CBT self-management plus usual care (e-CBT)…
- Trial name
- NCT03304613
- Testing
- Web-based Cognitive Behavioral Therapy (e-CBT) Self-Management, Promoting Resilience through Innovative Self-Management
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Malignant Solid Neoplasm
Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams
This clinical trial evaluates an educational program called Algorithm-Enabled Patients Activated in Cancer Care Through Teams (A-PACT) for reducing unplanned hospital visits and improving goals of care conversations with…
- Trial name
- NCT07278739
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- 7 sites in United States
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- SWOG Cancer Research Network
Alzheimer's Disease, Mild Cognitive Impairment
Brain-Computer Interface System for Training Memory and Attention in Elderly
The primary objective is to examine the efficacy of 8-weeks of a locally developed brain-computer interface based system intervention for improving attention and memory in healthy elderly and those with age related cognitive…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Cognitive Decline, Dementia
- Trial name
- NCT02228187
- Testing
- Brain-Computer Interface
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Colorectal Carcinoma
A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial
This clinical trial studies whether an intervention that addresses two or more levels of care (multilevel intervention) increases follow-up of abnormal, non-invasive, colorectal cancer (CRC) screening test results.
- Trial name
- NCT06822530
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Glycaemic Index, Glycaemic Response
Establishing the Glycaemic Index of Vegetable Smoothies
Glycaemic responses to carbohydrates ingested as fruit and vegetables may vary depending on factors inherent to the fruit or vegetable, and on the type of sugar.
- Conditions
- Glycaemic Index, Glycaemic Response, Glycaemic Response Measurements
- Trial name
- VEG-GI (NCT07729631)
- Testing
- Vegetable Smoothie
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Bath
Cancer, Anxiety
An Adaptive Dyadic Self-directed Coping and Self-management Skills Training Intervention for Caregivers of Individuals With Cancer
High-quality cancer care in Canada relies on family caregivers. Since cancer treatment is provided more and more in outpatient clinics, family caregivers now provide most of the support and care patients need when they return…
- Trial name
- NCT04255030
- Testing
- Coping Together Booklets and Workbook, Lay telephone coaching, Motivational Interviewing
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Cigarette Smoking
Health-Kit Enabled Mobile App for Tobacco Cessation
Tobacco use is the leading preventable cause of death in the US, contributing to more than 480,000 premature deaths each year. The Tobacco Treatment Guidelines underscore the need to offer patients who use tobacco products brief…
- Trial name
- NCT06292130
- Testing
- refresh
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Nursing Caries
The Effect of Standardised Patient Simulation in Nursing Education
With the coronavirus outbreak, the experience of nursing students with personal protective equipment is one of the issues of interest.
- Trial name
- NCT06566924
- Testing
- Control, Training Group for Standardised Patient Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Diabetes Mellitus, Quality of Health Care
Randomised Controlled Trial of Structured Personal Care of Type 2 Diabetes Mellitus
The aims of a concluding 14-year follow-up study are: To investigate what long-term effect the project model for structured, personalized diabetes care has on 1) the patients' mortality and development of diabetic complications…
- Conditions
- Diabetes Mellitus, Quality of Health Care, Health Services Research
- Trial name
- DCGP (NCT01074762)
- Testing
- Structured personal care
- Where
- Denmark
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis
This clinical trial examines the acceptability and effect of a parenting support intervention for families coping with solid tumor that has spread to other places in the body (metastatic) or has come back (recurrent).
- Trial name
- NCT05059678
- Testing
- Best Practice, Educational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Diseases, Cardiovascular Risk Factor
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials
Traditional randomized clinical trials (RCTs) have provided extremely valuable information on medical therapies and procedures that have changed the way heart diseases are treated.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Dyslipidemias
- Trial name
- NCT04067297
- Testing
- Lipid management toolbox
- Where
- Canada
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Evaluative Sciences
Pain, Incontinence, Urinary
Sumamos Excelencia 2022
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Conditions
- Pain, Incontinence, Urinary, Obesity, Childhood, Breastfeeding
- Trial name
- NCT05466656
- Testing
- Continuous quality improvement cycle model
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Gingivitis
Frankincense and Herbal Extracts for Plaque-Induced Gingivitis: A Double-Blind RCT
Frankincense, a natural resin obtained from trees of the Boswellia genus, has been traditionally used for its medicinal properties.
- Trial name
- FHEPIG (NCT07535229)
- Testing
- Frankinscence and coconut Oil based mouthwash, Frankinscence and Thyme essence/ water based mouthwash, Chlorhexidine (0.2%)
- Where
- Oman
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Oman Dental College
Diet Quality
Understanding Food Choices in Saudi Arabia
Using a 3-arm randomized controlled trial, the investigators aim to rigorously evaluate the effects of two front-of-pack (FOP) food labels on diet quality.
- Trial name
- NCT05007184
- Testing
- Chilean Warning Labels, Nutri-Score Labels
- Where
- Singapore
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Infiltration, Intravenous
The Effect of Care Bundle in Preventing the Frequency of Peripheral Intravenous Catheter-related Infiltration and Phlebitis in the Pediatric Emergency Department
This quasi-experimental study evaluates the effectiveness of a care bundle in preventing peripheral intravenous catheter (PIVC)-related infiltration and phlebitis in pediatric emergency department patients.
- Conditions
- Infiltration, Intravenous, Phlebitis, Pediatrics
- Trial name
- NCT07649499
- Testing
- Care Bundle for PIVC Management
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
No Condition, Basic Science
Effects of Post-activation Performance Enhancement Protocols on Judo-specific Performance: a Randomized Crossover Trial
The study aimed to investigate the post-activation performance enhancement (PAPE) of the special judo fitness test (SJFT) of youth judo athletes using upper-body (isometric push-ups), lower-body (standing broad jumps), or their…
- Trial name
- NCT06768723
- Testing
- Warm-up (specifically, Post-Activation Performance Enhancement)
- Where
- Portugal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Chronic Disease
Guided Care: Integrating High Tech and High Touch
The purpose of the study is to evaluate the effect of a Guided Care nurse on the quality of the health and well-being of the frail elderly.
- Trial name
- NCT00121940
- Testing
- Guided Care
- Where
- United States
- Volunteers
- 904 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetes Mellitus, Distress, Emotional
Indigenous Youth and Young Adults With Diabetes Peer Mentorship Program
The goal of this study is to learn if an Indigenous led peer-mentor program can provide Indigenous youth and young adults with the support needed to improve their distress and improve their diabetes control.
- Trial name
- NCT06430203
- Testing
- Peer mentoring
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre