Clinical trials: Blood sampling
Pulmonary Edema
Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema
Immersion Pulmonary Edema (IPE) is a relatively new form of hemodynamic pulmonary edema. The number of cases has been increasing over the last ten years and it has become the second most common cause of hospitalization for…
- Trial name
- RFSI-OPI (NCT05049889)
- Testing
- Terrestrial exercise, Swimming exercise, Transthoracic cardiac ultrasound
- Where
- 2 sites in France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Ultra-marathon Runners
Fatigability Compared Men and Women Induced According to the Distance Traveled on an Ultra-marathon in the Mountains
Acute physiological consequences of ultra-marathon running are still unknown, particularly in women. Some studies have suggested that the proportion of fatigue attributable to peripheral and central mechanisms varies between…
- Trial name
- UTMB_2019 (NCT04025138)
- Testing
- Neuromuscular tests in isometric mode, Transcranial Magnetic Stimulation (TMS), Neuromuscular fatigue assessment test
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Bacteraemia Post Debridement
PVP Iodine Effect on Post Debridement Bacteraemia
The study investigates the effect of supra- and subgingival rinsing of 10% PVP prior to ultrasonic debridement in patients with periodontitis (as compared to rinsing with water) in terms of post treatment bacteraemia.
- Trial name
- PJB 1 (NCT01647347)
- Testing
- Supra- and subgingival rinsing with 10% PVP-iodine, Water
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Intensive Care Medicine, ARDS
Change of Immune Cell of ARDS Patients：an Observational Study
To evaluate change of different immune cellsduring ARDS and its impact on prognosis.
- Trial name
- NCT02958748
- Testing
- taking blood sample
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Sports Drug Abuse
Can Anti-asthmatic Medication Improve Sprint Performance in Healthy Endurance Athletes?
The prevalence of asthma among athletes is higher than in the normal population and endurance athletes are especially at increased risk.
- Trial name
- NCT04402658
- Testing
- Inhaled salbutamol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Hypoxia, Altitude
Analysis of Protein and Emotional Alterations During and After Hypobaric Hypoxia
This study analyses both Protein Expression and emotional alterations during hypobaric hypoxia in volunteers of different groups.
- Trial name
- DRU-EMO-K (NCT03823677)
- Testing
- Hypoxia
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Myocarditis, Heart Failure
IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION
Magnetic properties of myocardial tissue change in the presence of disease. This is detectable in the change of rate of magnetic relaxation, and measurable by T1 and T2 mapping using cardiovascular magnetic resonance (CMR).
- Conditions
- Myocarditis, Heart Failure, Myocardial Fibrosis, Vascular Inflammation
- Trial name
- IMPReSSION (NCT04444128)
- Testing
- Cardiac Imaging
- Where
- Germany
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Rheumatic Diseases
Disease Activity in RA and SLE Patients and Its Relation to Muscle Performance,Fatigue and Blood Parameters
Assessment of disease activity in Rheumatoid Arthritis and Systemic lupus patients related to muscle performance, fatigue and blood parameters
- Trial name
- NCT03728231
- Testing
- Complete blood count
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy, Obesity
Sex Differences in Gene Expression in Human Adipose Tissue
This project was created to assess sex differences in adipose tissue gene expression in different locations in the body. The primary objectives are to understand: 1.
- Trial name
- NCT00677651
- Testing
- Adipose Biopsy, Blood sample, CT Scan
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Haematological Malignancies, Allogeneic Stem Cell Transplant
CD56+CD3- NK Cells Following Allogeneic Stem Cell Transplantation
The investigators propose a nonrandomized, Phase I study to assess the safety of infusion of NK cells that will be selected from sibling donors and infused to patients with hematological malignancies early following allogeneic…
- Conditions
- Haematological Malignancies, Allogeneic Stem Cell Transplant, CD56+CD3- NK Cells
- Trial name
- NCT01336478
- Testing
- Infusion of donor derived ex-vivo selected NK cells to patients after transplant, Haematology / Blood chemistry sampling
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
CRPS
Complex Regional Pain Syndrome (CRPS) and the Gut-bacteria
The purpose of this study is to investigate, for the first time, whether gut bacteria composition and function of patients with CRPS differ from those of healthy adults.
- Trial name
- NCT05473338
- Testing
- Stool and blood samples, Physical examination, Questionnaires
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Obstetric Labor Complications, Hemorrhage
Coagulation Factor Changes Associated With Postpartum Hysterectomies
The purpose of this study is to examine components of the coagulation system in women undergoing postpartum hysterectomy and to compare laboratory parameters of coagulation in these women to women at increased risk for a…
- Conditions
- Obstetric Labor Complications, Hemorrhage, Complications; Cesarean Section
- Trial name
- NCT00456547
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Diabetes Mellitus, Type 1, Diabetes Mellitus
Urine Extracellular Vesicles: Non-invasive Biomarkers of Β-cell Function and Novel Therapeutic Agents in Diabetes
Diabetes mellitus is a common chronic disease with a huge socioeconomic burden worldwide. Type 1 Diabetes(T1D) accounts for nearly 95% of diabetes in pediatric age and a lifelong dependence on exogenous insulin.
- Trial name
- EvsBioDiabetes (NCT06832215)
- Testing
- Blood and urine samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Brain Injuries
Improvised Explosive Device (IED) Level Blasting of Human Blood With Slosh Prevention
To monitor changes in indicators of red cell damage such as extracellular hemoglobin, potassium (K-ABL), and lactate dehydrogenase (LD) post blast exposure.
- Trial name
- NCT03018548
- Testing
- blood draw
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy Subjects
Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects
The goal of this study is to study the autoreactive lymphocytes in healthy volunteers. More specifically, this research aims to identify what distinguishes the autoreactive lymphocytes found in healthy individuals from those…
- Trial name
- REFLEX (NCT07898826)
- Testing
- Blood sampling at D0, Blood sampling at D0, M12 and M24
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
The Impact of Extreme Physical Exertion on Health, The Impact of Extreme Physical Exertion on Glucose
A Comprehensive Interdisciplinary Assessment of the Impact of Ultramarathons on the Health of Middle-aged and Older Amateur Runners - SUPERMARATON 2025 Project
The "Supermarathon 2025" study was designed as a prospective, interdisciplinary field study to assess the impact of extreme physical exertion, such as a 100-kilometer ultramarathon, on the health of individuals aged ≥ 45 years.
- Conditions
- The Impact of Extreme Physical Exertion on Health, The Impact of Extreme Physical Exertion on Glucose, The Impact of Extreme Physical Exertion on Respiratory System, The Impact of Extreme Physical Exertion on Joints and Muscles
- Trial name
- NCT07451717
- Testing
- Blood and urine analysis
- Where
- Poland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Pancreatic Neuroendocrine Tumor, Solid Pancreatic Neoplasms
Plasma cfDNA Fragmentomics for Early pNET Detection and Differential Diagnosis of Solid Pancreatic Tumors
This prospective study aims to evaluate the sensitivity and specificity of an integrated model using fragmentomic profiles of plasma cell-free DNA for early detection of pancreatic neuroendocrine tumors and differential diagnosis…
- Trial name
- NCT05847855
- Testing
- Blood collection
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Glomerulopathy, C3G
Pilot STUDY to Monitor Ex-vivo the Biological Effects of the C3 Inhibitor, PEGCETACOPLAN, on Activation of Complement in Fluid Phase and on Podocytes in Patients With C3G and Primary IC-MPGN
This is a prospective, multicenter, non-interventional, observational pharmacological real-world study to characterize longitudinal changes in ex vivo biomarkers of complement activation in patients with C3G and primary IC-MPGN…
- Conditions
- Glomerulopathy, C3G, Membranoproliferative Glomerulonephritis (MPGN)
- Trial name
- COMPASS (NCT07904338)
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Hepcidin
Hepcidin Behavior in Patients With Obesity and Bariatric Surgery
Iron deficiency is one of the most common nutritional problems observed in patients with obesity and after bariatric surgery. From a therapeutic point of view, iron deficiency can lead to iron deficiency anemia.
- Trial name
- HOBS (NCT03990948)
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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