Clinical trials: Caffeine
Neutrophil Chemotactic Response
Influence of Lifestyle Factors on Neutrophil Migration Pilot Study
This study will determine how common lifestyle practices affect the behavior of neutrophils (a type of immune cell) at shorter time scales than previously possible.
- Trial name
- NCT02411318
- Testing
- Exercise, ProLab 200mg caffeine capsule, Ethanol ingestion
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aerobic Gymnastics Performance, Sports Performance
Combined Rhodiola Rosea and Caffeine Supplementation for Aerobic Gymnastics Performance
Aerobic gymnastics requires repeated explosive movements, upper-body support elements, and the ability to maintain performance under fatigue.
- Conditions
- Aerobic Gymnastics Performance, Sports Performance, Exercise Recovery, Nutritional Supplementation
- Trial name
- NCT07860242
- Testing
- Rhodiola rosea Supplementation, Caffeine Supplementation, Standardized Aerobic Gymnastics Training
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Oral Hygiene, Oral Health
Oral Hygiene Among Portuguese Older Adults
The goal of this clinical trial was to compare two different oral hygiene instruction methods on oral hygiene behavior in older adults.
- Conditions
- Oral Hygiene, Oral Health, Older
- Trial name
- NCT06444490
- Testing
- General Approach Instruction, Personalised Technique Instruction
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Ischemia Reperfusion Injury, Endothelial Function
The Metformin-FMD Trial
In acute myocardial infarction early restoration of coronary blood flow is the most effective strategy to limit infarct-size. Paradoxically, reperfusion itself also aggravates myocardial injury and contributes to final infarct…
- Trial name
- MetFMD (NCT01610401)
- Testing
- Metformin, Pretreatment with metformin in combination of infusion of caffeine., No pretreatment with metformin in combination with infusion of caffeine
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
High Myopia, Choroid
Effect of Caffeine on Ocular Circulation in High Myopes
To investigate the effect of caffeine on ocular circulation by using Optical Coherence Tomography and Optical Coherence Tomography Angiography.
- Trial name
- NCT03294967
- Testing
- Caffeine, Vitamin E
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Normal Controls
Herbal Extract Study
The objective of this study is to assess the effects of an herbal extract on mental energy in healthy human subjects.
- Trial name
- NCT02095301
- Testing
- Herbal Beverage
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy Adult Male
Acute Effects of Caffeine on Repeated Sprint Performance and Energy Distribution
The goal of this study is to learn if low-dose caffeinated coffee improves repeated sprint performance and affects energy system contributions in combat sports athletes.
- Trial name
- NCT07596511
- Testing
- Cycling Repeated Sprint Test (6 × 10 s), Breath-by-Breath VO₂ Monitoring - COSMED K5, Capillary Blood Lactate Sampling (non-invasive)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Trabzon University
Poor Quality Sleep
Project REST: Club Sports
Evidence suggests that student athletes frequently experience sleep problems and are aware of the impact of sleep loss on mental and physical outcomes.
- Trial name
- NCT07103759
- Testing
- Refrain from caffeine techniques, Project REST Platform
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Anesthesia
A Study to Determine if Caffeine Accelerates Emergence From Propofol Anesthesia
At present clinicians have no way to reverse anesthesia. Patients wake when their bodies clear the anesthetic. Most people wake quickly, but some do not.
- Trial name
- NCT03360903
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Withdrawal Symptoms
The Potentially Addictive Properties of Soda: A Feasibility Study
The purpose of this study to investigate the addictive properties of soda and other sugar sweetened beverages (SBBs) in teenagers aged 13-18 years.
- Trial name
- NCT02044757
- Testing
- SSB withdrawal
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Balance Assessment, Performance
The Effect of Hand Position on Balance
This study employed a single-group repeated measures design, conducted in accordance with the STROBE reporting guidelines. Nineteen participants who met the inclusion criteria were recruited.
- Trial name
- NCT07111923
- Testing
- Balance Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Energy Expenditure, Cognition
A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, Reaction Time, and Other Perceptual Indicators
The purpose of this study is to evaluate the changes in energy expenditure, fat oxidation, reaction time, and perceptual indicators of energy and focus after acute ingestion of a caffeine-based energy drink.
- Conditions
- Energy Expenditure, Cognition, Reaction Time
- Trial name
- ASH (NCT05998096)
- Testing
- Caffeine-Based Energy Drink
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Dehydration, Dehydration Related to Exercise
The Impact of a Caffeinated Sports Drink on Performance
Caffeine is known to enhance physical and mental performance, but few beverages combine caffeine with electrolytes and carbohydrates to enhance exercise performance.
- Trial name
- NRG (NCT06721793)
- Testing
- carbohydrate electrolyte drink, no-sugar electrolyte drink, Caffeinated Carbohydrate and electrolyte drink
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Fatigue
Evaluate the Effectiveness and Safety of the Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health
The purpose of this study is to assess the effectiveness and safety of the Alpinia galanga formulation, Theacrine formulation, and Caffeine formulation on fatigue, mental acuity, and cognitive health among overall healthy…
- Trial name
- NCT05170113
- Testing
- Alpinia galanga formulation, Theacrine formulation, Caffeine formulation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Esports, Caffeine
Effects of Caffeine, L-Theanine, and Diaphragmatic Breathing on Esports Players' Performance
The purpose of this study is to investigate whether caffeine, L-theanine (a natural amino acid found in tea), and diaphragmatic breathing exercises can help improve the game performance of esports players.
- Conditions
- Esports, Caffeine, L-theanine
- Trial name
- CLD Esports St (NCT06621797)
- Testing
- Intervention 1: Dietary Supplement - Caffeine Supplement, Intervention 2: Dietary Supplement - Caffeine + L-Theanine Supplement, Intervention 3: Dietary Supplement - Caffeine Supplement + Diaphragmatic Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
Effects of Neo40(TM) With Caffeine on Cycling Time Trial Performance
Acute supplementation of Neo40(TM), a nitrate lozenge, will improve cycling performance
- Trial name
- NCT01710761
- Testing
- Nitrate supplement with caffeine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy, Type 2 Diabetes
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
- Conditions
- Healthy, Type 2 Diabetes, Obesity
- Trial name
- NCT05264727
- Testing
- Dextrose, Clinisol 15%
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking
Effects of Smoking Environment on Craving and Smoking
The goal of this study is to evaluate the effects of exposure to standard smoking environments on ability to resist smoking as measured with a Delay to Smoking Task.
- Trial name
- CC2pilot (NCT02416986)
- Testing
- 6 hour smoking abstinence, Delay to Smoking Task (smoking cues), Delay to Smoking Task (nonsmoking cues)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Variation in the Impact of Coffee on the Metabolic Rate
The purpose of this study is to explore variation in the impact of coffee on metabolic rate. The investigators plan to recruit healthy participants, half male and half female.
- Trial name
- NCT06432504
- Testing
- Caffeine content
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Pharmacokinetic Study in Healthy Volunteers
Kinetics of Yohimbine in Humans to Explore Sex and CYP2D6 Genotype Interactions
This study investigates the pharmacokinetics of yohimbine in women and men aged 18 to 40 years to explore sex-specific differences in CYP2D6-dependent drug metabolism.
- Trial name
- YOKI-1 (NCT06939608)
- Testing
- Yohimbine, ¹³C₃-caffeine
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald