Clinical trials: Probiotic
Stress, Psychological, Healthy
A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress
The purpose of this clinical trial is to determine whether Probiotic can modulate the psychological stress experienced by healthy medical, dental and health science students preparing for university/institute of technology…
- Trial name
- NCT04125810
- Testing
- Probiotic
- Where
- 7 sites in Ireland, United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Danisco
Stress, Attention Disturbances
Impact of Probiotic Supplementation on Cognition and Related Health Outcomes Among Video Gamers
The primary objective of the current study is to investigate the effect of two probiotic formulations on task-switching following acute stress in healthy, adult action video gamers.
- Trial name
- NCT05545813
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Survival of Probiotics During GI Transit, GI Symptoms
Acidophilus Pearls Fecal Recovery Study
Commercial probiotics can be delivered in numerous forms. The two most common delivery forms are similar to the two product formats to be tested.
- Trial name
- NCT02001610
- Testing
- Acidophilus pearls, Hard shell gelatin capsules
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Wound
Effect of Probiotics on Oral Wound Healing - Pilot Study
This research will study the healing of standardized wounds created in the oral mucosa of volunteer participants during daily intake of tablets and topical application of oil containing the probiotic bacterium Lactobacillus…
- Trial name
- PROWOUND (NCT03210779)
- Testing
- L. reuteri DSM 17938/ATCC PTA
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Allergic Conditions
Primary Prevention of Allergic Disease in Early Child by Lactobacillus Reuteri
An altered microbial exposure may be partly responsible for the increase of allergic diseases in populations with a western lifestyle.
- Trial name
- NCT01285830
- Testing
- Lactobacillus reuteri
- Where
- 3 sites in Sweden
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Skin Problems
Efficacy Evaluation of the Probiotics Containing Skincare Products on Skin
Previous studies on skin health with Lactic acid bacteria (LAB) have been published for many years, including prevention of skin diseases and improvement of skin conditions.
- Trial name
- NCT03350893
- Testing
- Emulsion base with probiotics, Emulsion base
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GenMont Biotech Incorporation
Tuberculosis
Safety and Immunogenicity of Nyaditum Resae® Probiotic to Protect From Tuberculosis
This is a double-blind, masked, compared with placebo clinical trial in healthy volunteers with or without tuberculosis infection.
- Trial name
- NCT02076139
- Testing
- Nyaditum resae® 10e4, Nyaditum resae® 10e5, Distilled water
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Manresana de Micobacteriologia, SL
Functional Abdominal Pain Syndrome
The Effects of Probiotics, Lactobacillus GG, in the Treatment of Abdominal Pain in Children With Functional Abdominal Pain Disorders
Recurrent or chronic abdominal pain is one of the common gastrointestinal problems in children. While most children do not have organic origins (so called functional abdominal pain disorders; FAPDs), the symptoms can nevertheless…
- Trial name
- NCT06310733
- Testing
- LGG
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Atopic Dermatitis
The Effects of Probiotics in Atopic Dermatitis
The purpose of this study is to study the clinical effects of taking probiotics in patients who have moderate to severe atopic dermatitis.
- Trial name
- NCT00378300
- Testing
- Oral Probiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy Adults
Prospective Tolerability Assessment of a Probiotic Dietary Supplement
The dietary supplement being investigated is a formula containing a combination of eight probiotic strains. The combination formula was developed to support general gastrointestinal and immune health.
- Trial name
- NCT04044144
- Testing
- Probiotic Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Women With IBS-C
A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
The purpose of this study is to evaluate the effect of a commercially available fermented dairy product containing probiotics (4 weeks, twice a day) on abdominal distension in IBS patients with constipation (IBS-C).
- Trial name
- NCT01097993
- Testing
- 1-fermented dairy product, 2- milk-based non-fermented dairy product (control product)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Halitosis, Probiotics
The Effect of Oral Probiotics on Oral Hygiene and Halitosis in Orthodontic Patients.
Brackets, bands, ligatures and wires in patients receiving orthodontic treatment with fixed appliances are areas that trap food and impede oral hygiene.
- Conditions
- Halitosis, Probiotics, Orthodontic Appliance Complication
- Trial name
- NCT05651503
- Testing
- Probiotics
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Dysbiosis
Effect of Probiotic on Gut Microbiome and Bacterial Translocation in Healthy Asian Volunteers
Dysbiosis of the gut microbiome has been recognized to underlie the pathogenesis of various gastrointestinal conditions. Probiotics are known to exert beneficial effects on gut health and have great potential for use as…
- Trial name
- NCT05083572
- Testing
- Colonic lavage with polyethylene glycol, Probiotic, Antibiotic
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Immune
Beverage for Immune Support
Evaluate the effects of a beverage supplement on immune health over an 8 week intervention using either a placebo or active supplement.
- Trial name
- NCT05566314
- Testing
- Amunizer
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Healthy, Elderly
Study to Evaluate the Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Elderly Subjects
This is a phase I, open label clinical trial to evaluate the safety of Lactobacillus rhamnosus GG (LGG) in elderly subjects. Lactobacilli are part of the normal flora of the intestine.
- Trial name
- NCT01274598
- Testing
- Lactobacillus Rhamnosus GG, ATCC 53103 (LGG)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vulvovaginal Candidiasis
Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal Candidiasis
This study evaluates the effect of a multi-strain probiotic on the risk of recurrence and severity of symptoms in females with recurrent vulvovaginal candidiasis (R-VVC).
- Trial name
- PROVELIA (NCT06480604)
- Testing
- Probiotic
- Where
- 6 sites in India
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Gastrointestinal Tolerance of Probiotics in Infants
Evaluating the Impact of Synbiotic Supplementation on Infants and Toddlers
Background and Significance: Bifidobacterium longum subspecies infantis (B. infantis) and other infant associated Bifidobacterium (such as Bifidobacterium longum subspecies longum and Bifidobacterium breve) are known to be…
- Trial name
- NCT06746285
- Testing
- Synbiotic Supplement
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Persephone Biosciences
Healthy Response to Probiotics
Defining the Normal Human Response to Probiotics
The study is a mono-center, randomized, semi-blinded, placebo-controlled, cross-over, proof-of principle study in healthy volunteers. The study will determine the probiotic effect of LGG on intestinal tissue and intestinal cells
- Trial name
- NCT03140878
- Testing
- LGG
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Infectious Diseases
Severe Necrotizing Enterocolitis in Preterm Newborns <1500g Using Probiotics
The purpose of this study is to know the effects of probiotics on the incidence of Necrotizing Enterocolitis (NEC) in preterm infants less than 1500 g.
- Trial name
- EPP (NCT02226263)
- Testing
- probiotics Lactobacillus acidophilus boucardii
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Colic
Probiotics Strains for Infant Colic
Interest in the use of probiotics as a potential treatment to reduce crying in babies with colic has increased lately. Recent studies have reported that the gut microbiota in infants with colic is characterized by lower…
- Trial name
- NCT05685030
- Testing
- Limosilactobacillus reuteri CCT 7862, Bifidobacterium lactis CCT 7858 + Lactobacillus rhamnosus CCT 7863
- Where
- Brazil
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
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