Clinical trials: Radiation
Pulmonary Ventilation
Accuracy of 3D Electrical Impedance Tomography for Assessing Lung Ventilation
This prospective observational study will evaluate how accurately three-dimensional electrical impedance tomography (3D-EIT) measures the distribution of air in the lungs during breathing when compared with four-dimensional…
- Trial name
- NCT07756086
- Testing
- Three-Dimensional Electrical Impedance Tomography, Dynamic Chest Computed Tomography
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Solid Tumors, Carcinoma
Safety and Diagnostic Performance of 111In-TJD-31 SPECT Imaging in Patients With Solid Tumors
This study aims to evaluate the performance of a novel SPECT imaging agent, 111In-TJD-31, which targets placental alkaline phosphatase (ALPP).
- Conditions
- Solid Tumors, Carcinoma, Ovarian Neoplasms, Endometrial Neoplasms Malignant
- Trial name
- NCT07815951
- Testing
- 111In-TJD-31 Injection
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yong He
Colorectal Cancer
Implication of Genetic Variations in Long Intergenic Non-coding RNA 00511 (LINC00511) in Colorectal Cancer
As, there is a lack of information about the association between LINC00511 SNP(s) variants and CRC susceptibility, so this study was undertaken to address whether these SNPs would increase CRC risk or could predict its prognosis.
- Trial name
- NCT06534242
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Patient Satisfaction, Patient Preference
Focus Group Interview Study on Patient Experiences and Satisfaction
In order to improve quality of care at the department, the investigators will perform a focus group interview study with patients and family members.
- Trial name
- RT_Focus (NCT04625842)
- Testing
- Focus group interview
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Fine Lines, Wrinkles
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin…
- Conditions
- Fine Lines, Wrinkles, Photoaging
- Trial name
- NCT04545970
- Testing
- Facial cleanser, Facial moisturizer, Sunscreen
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Thyroid Associated Ophthalmopathy
Construction and Application of Precise Diagnosis and Treatment System for Thyroid-associated Ophthalmopathy
This study aims to develop the deep learning-based system that integrates multimodal information to automatically diagnose, stage, and grade thyroid-associated ophthalmopathy (TAO), assist in treatment decision-making, and…
- Trial name
- NCT07124572
- Testing
- Imaging and ocular examinations
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Tako-tsubo Cardiomyopathy
Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation?
Tako Tsubo Cardiomyopathy (TTC), also known as "Broken Heart Syndrome", is a disorder of the heart that occurs most commonly in women (although it occasionally occurs in men) and is usually related to a stressful event.
- Trial name
- TERRIFIC (NCT02897739)
- Testing
- Magnetic resonance imaging, Acute Inflammatory Activation study, PET CT
- Where
- United Kingdom
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Dental Enamel Hypoplasia
Laser Used in the Treatment of Hypomineralized Occlusal Lesions in Teeth Enamel Affected by MIH
Background: Nowadays an increase in the incidence of teeth affected by molar incisor hypomineralisation (MIH) has been observed.
- Trial name
- NCT03614819
- Testing
- Diode laser group, Glass Ionomer Sealing Group
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tuberculosis
Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries
The ERASE - TB study will be conducted in order to fill a critical unmet need for tuberculosis control. Persons who are in contact with an infectious TB case may become infected themselves.
- Trial name
- ERASE-TB (NCT04781257)
- Testing
- New test candidates
- Where
- 3 sites in Mozambique, Tanzania and 1 more
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Michael Hoelscher
Autoimmune Diseases, Sickle Cell Disease
Microvascular and Fibrosis Imaging Study
In this study, Laser Doppler Flowmetry (LDF), Laser Doppler Imaging (LDI), Orthogonal Polarization Spectral Imaging (OPSI), Nail fold video capillaroscopy (NVC) and Optical Coherence Tomography (OCT) will be used to assess…
- Conditions
- Autoimmune Diseases, Sickle Cell Disease, Chronic Graft Versus Host Disease
- Trial name
- NCT01758250
- Testing
- Acoustic Radiation Force Impulse (ARFI), Laser Doppler Flowmetry (LDF), Laser Doppler Perfusion Imaging (LDI)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Duke University
Assessment, Self, Muscle Atrophy
Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.
The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for…
- Conditions
- Assessment, Self, Muscle Atrophy, Ultrasound Therapy; Complications, Aging
- Trial name
- DIASEM (NCT04753450)
- Testing
- No intervention
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Diagnostic Imaging
Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers
PET (positron emission tomography) imaging with BAY85-8102 F-18, DPA-714 for investigation of neuroinflammation pattern in probable Alzheimers patients versus healthy volunteers and radiation dosimetry in healthy volunteer.
- Trial name
- NCT01009359
- Testing
- F-18 DPA-714 (BAY85-8102)
- Where
- 2 sites in Finland, Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Bayer
Osteoarthritis, Hip
Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA)
This study compares the change (loss) of bone mineral density (BMD) that occurs in the proximal femur after hip resurfacing and total hip replacement.
- Trial name
- NCT01359527
- Testing
- Hip Resurfacing, Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Vitamin D Production in the Skin, Sunscreen Persistence
Sunscreen: Persistence of Sun Protection Factor and the Influence on Vitamin D
The investigators want to investigate whether sunscreen is removed by clothing and to what extend when the amount of sunscreen applied varies.Does clothing reduce the SPF when clothes are put on 20, 8, or 4 minutes after…
- Trial name
- sunscreen (NCT00711256)
- Testing
- sunscreen MATAS sunlotion SPF 8, UVB light
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Dermatitis, Phototoxic
Study to Learn More About the Potential of Antifungal Cream V61-044 Containing Trolamine to Cause Irritant Reaction of the Skin to Ultra Violet Light in Healthy Human Subjects
In this study researchers want to gather information about the potential of Antifungal Cream V61-044 containing Trolamine to produce a phototoxic reaction on the skin.
- Trial name
- NCT04531527
- Testing
- Butenafine HCl 1% (BAY1896425)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Nasopharyngeal Carcinoma
The Value of Post-radiation Detectable Plasma EBV DNA in High-risk Nasopharyngeal Carcinoma Patients
An additional blood test at 2-3 months after RT is a valuable biomarker in predicting treatment outcome for NPC patients. Patients with persistently detectable EBV DNA during re-staging survey 2-3 months after RT should…
- Trial name
- NCT03981224
- Volunteers
- 706 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Melasma
DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide.
BACKGROUND: Malar melasma has a chronic and recurrent character that may be related with epigenetic changes.
- Trial name
- NCT03392623
- Testing
- Retinoic acid, colorimetry measurement, sunscreen
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Breast Cancer
The Effect of Aromatase Inhibitors on Cardiovascular Risk Factors in Women With Breast Cancer
This study explores how aromatase inhibitor therapy affects risk factors for heart disease in postmenopausal women with breast cancer.
- Trial name
- Silhouette (NCT01080170)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Orofacial Pain, Tension-Type Headache
Photobiomodulation Dosimetry s in Patients With Orofacial Pain
This project aims to validate a dosimetry model for photobiomodulation treatment in patients with orofacial pain and tension-type headache symptoms. The study will involve 240 participants divided into four age groups.
- Trial name
- NCT06065969
- Testing
- Photobiomodulation
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Short Stature, Growth Disorders
Bone Age Assessment in Children Using Ultrasound Compared to Wrist X-ray
Bone age assessment in children is based on the interpretation of hand x-ray scans according to Greulich and Pyle (GP) standard atlas and frequently used for evaluating growth and puberty in children and adolescents.
- Trial name
- NCT03123003
- Testing
- SonicBone Ultrasound, Wrist X-ray
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
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