Clinical trials: SBRT
Prostate Adenocarcinoma
Phase II Trial of SBRT + or - IMRT in Treatment of Patients With Clinically Confined Prostate Adenocarcinoma
Patients with locally confined prostate adenocarcinoma (clinical stage T1c - T2bN0M0, Gleason score 7, PSA 20 ng/ml) are assigned to one of two treatment arms.
- Trial name
- NCT02339948
- Testing
- SBRT
- Where
- 4 sites in United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- GenesisCare USA
Lymph Node Cancer Metastatic
High Dose SBRT for Abdominal-Pelvic Lymph Nodal Lesions in Oligometastatic Patients
This is a prospective, multicentric, phase II and feasibility study aimed to address early and late side effects of hypofractionated ablative radiotherapy for oligometastatic patients with lymph node metastases for…
- Trial name
- NCT02570399
- Testing
- Oligometastatic patients with abdominal-pelvic lymph nodes
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Prostate Cancer
Metabolomic Study for Localized Prostate Cancer
Prostate cancer is a common disease in men treated using surgery, radiation therapy and/or hormonal therapy. Clinical prognosis relates to stage and grade of disease.
- Trial name
- NCT01968538
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Non-Small-Cell Lung Cancer, Carcinoma
Locally Invasive NSCLC Treated With NEo-Adjuvant Stereotactic Body RadioTherapy and REsection
Despite improved staging and operative techniques, the rate of incomplete resection (R1) of NSCLC has remained significant over the last decades.
- Trial name
- LINNEARRE-I (NCT02433574)
- Testing
- Neoadjuvant Stereotactic body radiation (SBRT)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Juravinski Cancer Center
Hepatocellular Carcinoma
RT+ Anti-PD-1 for Patients With Advanced HCC (RT+PD-1-HCC)
Hepatocellular carcinoma (HCC) is a common malignancy, and its incidence is expected to increase in many countries in coming decades. Approximately 70-80% of newly diagnosed HCC patients already have advanced disease.
- Trial name
- NCT04193696
- Testing
- Radiation therapy and systemic anti-PD-1 immunotherapy for patients with advanced hepatocellular carcinoma
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Bone Metastases, Radiotherapy Side Effect
A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases
In the present study, we will prospectively evaluate the pain response and treatment failure rate to determine the most favorable radiation dose in single fraction stereotactic radiotherapy using the modern highly conformal…
- Trial name
- NCT04063254
- Testing
- Stereotactic Radiotherapy
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
HepatoCellular Carcinoma
Comparison of SBRTand Repeat TACE for HCC
Comparison of Stereotactic Body Radiation Therapy (SBRT) and repeated transarterial chemoembolization (TACE) for Hepatocellular Carcinoma (HCC)as a Local Salvage Treatment after first incomplete TACE
- Trial name
- STH (NCT03326375)
- Testing
- SBRT
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gangneung Asan Hospital
Metastasis From Malignant Tumor of Soft Tissues
SBRT Treatment for Lung Metastasis From Soft Tissue Sarcoma
In this study the investigators treat PM oligometastatic patients with SBRT. Our objective is to evaluate rate of local control of treated lesions in patients treated with Intensity Modulated Radiation Therapy (IMRT) using…
- Trial name
- NCT02561559
- Testing
- Lung metastasis from soft-tissue sarcoma
- Where
- Italy
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Glioblastoma
Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2)
This is a prospective multicenter study of hypofractionated radiotherapy for the radiation treatment (RT) of solid tumors and in particular for Glioblastoma (in Aim 2).
- Trial name
- NCT06551909
- Testing
- Neoaddjuvant Stereotactic Radiotherapy with Simultaneous Integrated Boost
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Non Small Cell Lung Cancer
The APRIL Trial Evaluating Upfront Stereotactic Body Radiotherapy in Stage III Advanced Non-small Cell Lung Cancer
The aim of the study is to test the feasibility \& loco-regional control rate by combining high precision SBRT with chemotherapy in stage III NSCLC in tumor/lymph nodes if tumors/lymph node size with ≤ 6cms in size.
- Trial name
- APRIL (NCT07565987)
- Testing
- SBRT in stage III NSCLC
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Esophageal Squamous Cell Carcinoma, Oligometastatic Disease
Anti-PD-1 Immunotherapy Combined With SBRT for Patients With Oligometastatic ESCC
The goal of this phase II clinical trial is to explore the efficacy and safety of anti-PD1 combined with stereotactic body radiation therapy (SBRT) for patients with oligometastatic esophageal squamous cell carcinoma.
- Trial name
- NCT05626569
- Testing
- PD-1 combined with SBRT
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Hepatocellular Carcinoma
Transarterial Chemoembolization (TACE) With or Without Stereotactic Body Radiotherapy (SBRT) in Hepatocellular Carinoma
Hypothesis: Patients with hepatocellular carcinoma (HCC) have few options if they fail or are unable to undertake surgery, transarterial chemoembolization (TACE) and/or chemotherapy.
- Trial name
- TACERT (NCT03079778)
- Testing
- transarterial chemoembolization, TACE plus RT
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Radiation
Intensity-modulated Radiotherapy Protocol in Cervix Cancer
Definitive treatment protocol for high-dose intensity-modulated radiotherapy (IMRT) with intracavitary radiotherapy in locally advanced cervical cancer: A phase II trial
- Trial name
- NCT02993653
- Testing
- High-dose Intensity-modulated radiotherapy
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul St. Mary's Hospital
Nasopharyngeal Cancinoma (NPC), SBRT
SBRT Combined With Nimotuzumab and Tislelizumab for Oligoprogressive Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of Immunotherapy
This study is a single-arm, open-label, prospective, and exploratory investigation aimed at examining the short-term efficacy, specifically the objective response rate (ORR), of SBRT combined with Nimotuzumab followed by…
- Conditions
- Nasopharyngeal Cancinoma (NPC), SBRT, Immunotherapy
- Trial name
- NCT06676722
- Testing
- SBRT combined with Nimotuzumab followed by Tislelizumab
- Where
- 2 sites in China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University