Clinical trials: Transcranial Direct Current Stimulation
Real tDCS, Sham tDCS
Supporting Decisions With Transcranial Direct Current Stimulation in Healthy Young and Elderly Individuals
Decisions are part of the daily life. On the neuronal level, activity in the dorsolateral prefrontal cortex (dlPFC) is important during complex decisions (e.g., whether something is emotional for a person or not).
- Trial name
- NCT03959462
- Testing
- real anodal transcranial direct current stimulation
- Where
- Switzerland
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Bern
Transcranial Direct Current Stimulation, Healthy Participants
Transcranial Direct Current Stimulation Apparatus for Domiciliary Use
Neuromodulation is characterized as a technique whose principle neurostimulation to produce inhibition or cortical arousal. The tDCS (transcranial direct current stimulation) is a noninvasive brain stimulation method used to…
- Trial name
- NCT02408237
- Testing
- Active tDCS Ambulatory, Active tDCS Home use
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fatigue
Impact of Transcranial Direct Current Stimulation on Fatigability and Fatigue Induced by a Selective Attention Task
This research project is focusing on changes in mental fatigue due to transcranial direct current stimulation (tDCS) in healthy individuals.
- Trial name
- NCT02840214
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
Establish the Role of Premotor and Motor Cortices in tDCS-facilitated Speech Motor Learning
Groups of unimpaired participants will all receive speech motor training of nonwords, and six tDCS conditions will be compared: anodal tDCS over speech motor regions; cathodal tDCS over speech motor regions; anodal tDCS over left…
- Trial name
- NCT05804344
- Testing
- Anodal speech motor tDCS, Cathodal speech motor tDCS, Anodal IFG tDCS
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- New York University
Aging, Accidental Falls
Feasibility of Home-based tES for Older Adults at Risk of Falling
In this project, the investigators propose to demonstrate the feasibility of remotely-monitored, caregiver (or spouse)-administered, home-based tES (transcranial electrical stimulation) intervention to improve mobility in…
- Trial name
- NCT04732533
- Testing
- tES (transcranial electrical stimulation)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Chronic Stroke
tDCS and CO-OP in Chronic Stroke
This project seeks to evaluate the acceptability feasibility, practicality feasibility, and preliminary effect of combining transcranial direct current stimulation (tDCS) and metacognitive strategy training (MCST) in individuals…
- Trial name
- NCT04617548
- Testing
- tDCS and CO-OP Group
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Trigeminal Neuropathic Pain
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain
The main goal of this study to integrate techniques producing images of the brain (also called neuroimaging techniques) with non-invasive brain stimulation to investigate factors that may be associated with chronic pain in…
- Trial name
- NCT03003715
- Testing
- PET Scans, transcranial direct current stimulation (tDCS), MRI
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain
Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography…
- Trial name
- NCT06968689
- Testing
- transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Relapsing Remitting Multiple Sclerosis, Secondary-progressive Multiple Sclerosis
Improving Cognitive Aptitudes With tDCS in Patients With Multiple Sclerosis
Noninvasive brain stimulations (NIBS) will be used in MS patients with cognitive impairments to enhance their cognitive aptitudes.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Secondary-progressive Multiple Sclerosis, Cognitive Deficits, Motor Deficits
- Trial name
- MScog-tDCS (NCT02266121)
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Transcranial Direct Current Stimulation, Healthy
Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1
Non-invasive neuromodulation, such as transcranial direct current stimulation ( tDCS) , is emerging as an important therapeutic tool with documented effects on brain circuitry, yet little is understood about h ow it changes…
- Trial name
- MINUTES (NCT03896425)
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression, Anxiety
Enhancing the Effectiveness of Cognitive Behavioral Therapy Using Non-invasive Brain Stimulation
The purpose of the proposed study is to examine if a repeated treatment of High Definition Transcranial Direct Current Stimulation (HD-tDCS) can increase the functional connectivity between the left ventrolateral prefrontal…
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT05555056
- Testing
- MxN-9 HD-tES Stimulator (Soterix Inc.)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Transcranial Direct Current Stimulation
fMRI Analysis of Aging and Awareness in Conditioning
Cathodal Transcranial direct current stimulation (tDCS) was administered to the right parietal region in order to determine if this stimulation could disrupt awareness of the conditioned stimulus (CS) - unconditioned stimulus…
- Trial name
- NCT03655769
- Testing
- transcranial direct current stimulation
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Inflammatory Bowel Diseases
Transcranial Direct Current Stimulation and the Interaction Between Chronic Pain and the Intestinal Epithelial Barrier in Patients With Chronic Inflammatory Bowel Diseases (IBD)
In the study the investigators aim to test whether transcranial direct current stimulation (tDCS) induced pain reduction is in association with functional changes in the brain measured with magnetic resonance imaging (MRI) and…
- Trial name
- NCT03825900
- Where
- Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Aging
Optimizing tDCS to Improve Dual Task Gait and Balance
The objective of this study is to determine the acute effects of single sessions of optimized tDCS, conventional tDCS, and sham stimulation on dual task standing and walking in older adults who are free of overt disease yet who…
- Trial name
- OptiStim (NCT04295798)
- Testing
- Conventional tDCS, Optimized tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Aging
Brain Stimulation and Cognitive Training in Healthy Older Adults
The aim of this study is to investigate whether a tDCS-accompanied intensive cognitive training of working memory leads to performance improvement in healthy older individuals.
- Trial name
- TrainStim (NCT03838211)
- Testing
- Anodal tDCS, Intensive cognitive training
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Posttraumatic Stress Disorder, PTSD
TDCS-Augmented Prolonged Exposure Therapy
The purpose of this study is to determine the effects of a brain stimulation technique known as transcranial direct current stimulation, or tDCS, on the benefits of Prolonged Exposure therapy, or PE, which is an effective…
- Conditions
- Posttraumatic Stress Disorder, PTSD, Anxiety, Depression
- Trial name
- NCT04327362
- Testing
- Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cognitive Flexibility
Modulation of Cognitive Flexibility by Tyrosine Depletion and Transcranial Direct Current Stimulation
The dorsolateral prefrontal cortex (dlPFC) and dopamine (DA) have been implicated in the control of cognitive flexibility. However, while a great deal of what it is know regarding a causative relationship between cognitive…
- Trial name
- NCT03462303
- Testing
- Anodal tDCS and tyrosine depleted drink, Anodal tDCS and balanced drink
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Healthy
4 mA tDCS, Estrogen, and Leg Muscle Fatigability
The majority of transcranial direct current stimulation (tDCS) studies have failed to consider sex as a modulating factor. This neglect may partly account for the high inter-subject variability bemoaned by many tDCS investigators…
- Trial name
- NCT04471805
- Testing
- Transcranial direct current stimulation 4 mA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Motor Learning
How Many Days Would You Want to Practice a Skill to Achieve it?
Practice is required to improve your shot in basketball or to play a musical instrument. The learning of these motor skills can be further enhanced by non-invasively stimulating regions of the brain that control movements with…
- Trial name
- NCT03249961
- Testing
- Anodal TDCS, Transcranial Magnetic Stimulation (TMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre