Clinical trials: Transcranial Direct Current Stimulation
Post-Concussion Syndrome
Cerebellar TDCS for SRPCS Treatment
This study is investigating the immediate and long-term effects of bilateral cerebellar transcranial direct current stimulation on cognition, balance, and symptom severity in people with sports-related post-concussion syndrome.
- Trial name
- NCT04760899
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Electricity; Effects
HD-tDCS to Modulate Connectivity
The purpose of the proposed study is to broaden our understanding on the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) so that its clinical effects can be further improved.
- Trial name
- NCT05959551
- Testing
- high definition transcranial direct current stimulation (HD-tDCS)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Epilepsy, Seizures
Closed-loop System Using Transcranial Direct Current Stimulation (tDCS) for Epilepsy
In this pilot study, the researchers investigated the feasibility of a closed-loop electroencephalography (EEG) / transcranial direct current stimulation (tDCS) system for treatment of epilepsy.
- Trial name
- NCT01415362
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Healthy Older Adults
tDCS Effects on Associative Learning in Older Adults of Working Age
The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals.
- Trial name
- TRAINSTIM2 (NCT02795702)
- Testing
- tDCS, training
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy Older Adults
tDCS Effects on GABA Concentration and Brain Functional Connectivity in Older Adults Of Working Age
The aim of this study is to investigate whether anodal tDCS over the left M1 leads to a decrease of GABA concentration and alterations of functional brain connectivity in older people, compared to sham tDCS.
- Trial name
- TRAINSTIM1 (NCT02794272)
- Testing
- tDCS
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Autism Spectrum Disorder
Cerebellar tDCS in Children With Autism Spectrum Disorder
The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to…
- Trial name
- NCT04446442
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cognitive Impairment, Cognitive Decline
A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy…
- Trial name
- AIM (NCT05998031)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy
Cognitive Stimulation Study
This study will evaluate the influence of non-invasive brain stimulation on different elements of cognitive function in healthy persons between the ages of 18-90 years.
- Trial name
- CogStim (NCT02067689)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Florida
Other Forms of Epilepsy, Treatment Resistant
TDCs to Treat Drug-resistant Epilepsy
Epilepsy is the fourth overall neurologic disorder, regardless of age and gender, affecting more than 50 million people worldwide.
- Trial name
- NCT05825274
- Testing
- Active Cathodal tDCS
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
Tinnitus
Impact of Neurostimulation on Patterns of Brain Electrical Activity in Patients With Tinnitus
Relating the electroencephalogram findings of patients with tinnitus before and after a therapeutic modality is still scarce in the literature, especially with neuromodulatory methods, more specifically with Transcranial Direct…
- Trial name
- NCT03036137
- Testing
- Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects.
- Trial name
- NCT03486795
- Testing
- M1 stimulation, PMC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Healthy
4 mA tDCS, Estrogen, and Leg Muscle Fatigability
The majority of transcranial direct current stimulation (tDCS) studies have failed to consider sex as a modulating factor. This neglect may partly account for the high inter-subject variability bemoaned by many tDCS investigators…
- Trial name
- NCT04471805
- Testing
- Transcranial direct current stimulation 4 mA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Healthy
tDCS of the Left dlPFC: Effects on Information Processing
This study investigates how a non-invasive form of brain stimulation, called transcranial direct current stimulation (tDCS), affects brain activity and information processing in younger and older adults.
- Trial name
- NCT07168031
- Testing
- Active Transcranial Direct Current Stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Bern
Inter-individual Variability
Using Electroencephalography (EEG) and Transcranial Current Stimulation (tCS) to Study and Modulate Cognition Study
Inter-individual variability in responsiveness to interventions poses great challenges for translational neuroscience, and health care in general.
- Trial name
- NCT03293316
- Testing
- Transcranial Random Noise Stimulation
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Semantic Dementia
Evaluation of a Transcranial Stimulation With Direct Current on Language Disorders in Semantic Dementia
Within the spectrum of fronto-temporal lobar degeneration (FTLD) semantic dementia (SD) causes profound language dysfunction. SD damages semantic processing typically in the temporal poles (anterior temporal lobes, ATL).
- Trial name
- STIM-SD (NCT03481933)
- Testing
- Transcranial stimulation
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lewy Body Disease, Healthy Aging
Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment
Lewy body diseases (LBDs) represents a group of neurodegenerative disorders characterized by the abnormal accumulation of aggregates of α-synuclein protein leading to the formation of Lewy bodies (LB) and Lewy neurites resulting…
- Trial name
- LANG-LBD (NCT05847985)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Depression
Brain Glucose Metabolism During Transcranial Direct Current Stimulation
With this study we will be able to dose-dependently measure real-time glucose metabolism changes after non-invasively stimulating superficial parts of the dlPFC, a commonly used target in therapeutic tDCS applications.
- Trial name
- NCT02999607
- Testing
- transcranial direct current stimulation
- Where
- Austria
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Live Face Processing in Typically Developed Participants
Neural Mechanisms of the Social Brain
This study aims to understand the neural mechanisms that underlie synchronization of two brains during social interactions.
- Trial name
- NCT07457567
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
Behavioral and Neurophysiological Effects of Multichannel Executive Network tDCS Combined With Preferred Music Stimulation
This study aims at comparing the effects of transcranial direct current stimulation combined with music on neurophysiological outcomes in healthy participants.
- Trial name
- NCT04705532
- Testing
- tDCS, Music, White noise
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Liege
Healthy
Spectral Characteristics of Memory Transformation
Sometimes, it is necessary to re-learn a previously learned movement behavior, for example, a bad posture during the golf drive or while playing the piano.
- Trial name
- MEM_MOD (NCT05946616)
- Testing
- Transcranial alternating current stimulation (tACS) combined with behavioral intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina