Clinical trials: Transcranial Magnetic Stimulation
Healthy, Transcranial Magnetic Stimulation
Neuromodulation by Non-invasive Brain Stimulation
The main objective of this study is to estimate the effect of the neuromodulation on the behavioral performances during the access in semantics according to the age of the individuals.
- Conditions
- Healthy, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Trial name
- NEUROMOD (NCT03167931)
- Testing
- MRI + transcranial Magnetic Stimulation, transcranial electric stimulation + electroencephalogram
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Methamphetamine Use Disorder
Cerebellum-Prefrontal Paired-Pulse Stimulation for Methamphetamine Use Disorder
To investigate the mechanism and efficacy of a novel repetitive transcranial magnetic stimulation (rTMS) intervention model with paired cerebellar-medial prefrontal cortex (mPFC) pulses on methamphetamine use disorder patients…
- Trial name
- NCT06457230
- Testing
- Paired Associative Stimulation Targeting the Cerebellar-mPFC
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Mild Cognitive Impairment, Memory Loss
Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities
This is a pilot study of non-invasive transcranial magnetic stimulation (TMS) to improve memory in healthy adults. It will also examine treating memory deficits in older adults with amnestic mild cognitive impairment (aMCI), a…
- Trial name
- NCT03574207
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Depression Disorder, fMRI Research
Modulatory Effects of Personalized Transcranial Magnetic Stimulation (TMS) on Heart-Brain Coupling in Individuals With Depressive Tendencies
This study focuses on individuals with depressive tendencies and investigates the regulatory effects of Transcranial Magnetic Stimulation (TMS)-guided by personalized functional connectivity mapping-on heart-brain coupling in…
- Conditions
- Depression Disorder, fMRI Research, Heart-Brain Coupling
- Trial name
- NCT07753473
- Testing
- DLPFC-insula TMS, DLPFC-sgACC TMS, 10-20 F3 TMS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xidian University
Healthy Control Subjects
Impact of Spaced iTBS on Plasticity in the Motor Cortex
The goal of this clinical trial is to explore the effects of non-invasive brain stimulation protocols using intermittent theta-burst stimulation (iTBS) on brain plasticity in healthy, right-handed individuals aged 18 to 50 years.
- Trial name
- STEP-MC (NCT06735794)
- Testing
- Compressed iTBS, Spaced iTBS
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Cognitive Dysfunction
Probing Cortical Excitability and Cognitive Function With TMS
The overarching purpose of this study is to develop a technique that is capable of identifying neurophysiological biomarkers sensitive enough to detect preclinical dementia by integrating Transcranial Magnetic Stimulation (TMS)…
- Trial name
- NCT03652012
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Chronic Nonspecific Low Back Pain
Study Comparing Cortical Function and Dysfunction Tests in Low Back Pain
The purpose of this study is to explore the cortical regulation of the paraspinal muscles in chronic low back pain. These (possible) changes in regulatory mechanisms are being compared to other motor control tests in order to…
- Trial name
- NCT00924495
- Testing
- transcranial magnetic stimulation
- Where
- Finland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Other Conditions of Brain
Roflumilast and TMS Motor Plasticity
Repetitive transcranial magnetic stimulation (rTMS) uses a magnetic field to non-invasively induce electrical function within the brain.
- Trial name
- NCT06457191
- Testing
- Roflumilast, Intermittent theta-burst stimulation transcranial magnetic stimulation, Continuous theta-burst stimulation transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Autism Spectrum Disorder
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Researchers think brain development may be controlled by gamma-aminobutyric acid (GABA).
- Trial name
- NCT04798274
- Testing
- Continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depersonalization Disorder
Depersonalization Disorder: Therapeutic Effect of Neuronavigated Repetitive Transcranial Stimulation
The purpose of this study is to assess the therapeutic efficacy of transcranial magnetic stimulation in patients with depersonalization disorder.
- Trial name
- PERSONA (NCT02476435)
- Testing
- Active rTMS
- Where
- 2 sites in France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Beta Rhythm, Tactile Perception
Beta Events and Sensory Perception
Low-frequency brain rhythms in the alpha (8-14Hz) and beta (15-29Hz) bands are strong predictors of perception and functional performance in a range of tasks, and are disrupted in several disease states.
- Trial name
- NCT04062318
- Testing
- Online Active SI-Hand TMS, Online Active Control TMS
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Brown University
Closed-loop Brain Stimulation
Closed-loop tES-non-invasive Stimulation
The goal of this study is to establish if non-invasive closed-loop neuromodulation is an effective approach to enhance cognitive function in healthy 18-40 years old volunteers.
- Trial name
- CLIBM (NCT07671079)
- Testing
- Transcranial low intensity focused ultrasound (FUS), transcranial electrical stimulation, Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Brain Injuries
Cortical Contributions to Motor Sequence Learning
The long-term objective initiated with this study is to determine which brain areas functionally contribute to learning a motor skill.
- Trial name
- NCT04138953
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Depression, Schizophrenia
Effects of Noninvasive Brain Stimulation Techniques on BDNF Levels
The aim of this study is to investigate the effects of non invasive brain stimulation - NIBS - techniques (Electroconvulsivotherapy - ECT, transcranial Direct Current Stimulation - tDCS, repetitive transcranial magnetic…
- Trial name
- Plasti-Stim (NCT02652832)
- Testing
- non invasive brain stimulation
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Effects of Cerebellar Stimulation on Brain Activation
Cerebellar Involvement in Cognitive Sequencing
Although there is increasing recognition that the cerebellum is involved in cognition as well as motor function, the manner in which the cerebellum contributes to cognition is uncertain.
- Trial name
- NCT06108336
- Testing
- TMS during sequence-demanding task, No TMS during sequence-demanding task, TMS during non-sequence-demanding task
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cortical Excitability, Healthy
Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation
This study is investigating how two types of non-invasive brain stimulation, transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS), affect brain activity, and whether combining them produces…
- Conditions
- Cortical Excitability, Healthy, TMS, Menstrual Cycle
- Trial name
- NCT07635017
- Testing
- Transcranial Electrical Stimulation, Transcranial Magnetic Stimulation, TES + TMS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Healthy
Exploring the Cortical Hemodynamic Variability of Prefrontal iTBS: a Concurrent TBS/fNIRS Study
An increasing number of studies have used the intermittent theta-burst stimulation (iTBS) protocol to investigate neural plasticity non-invasively in the prefontal cortex in healthy humans and in patients with psychiatric…
- Trial name
- NCT06104462
- Testing
- Intermittent theta burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Neuromuscular Diseases
The Neuroimage Study of the Neuromuscular Disorders.
The neuromuscular disorders could be briefly divided to neuropathy, myopathy, motor neuron disease, and neuromuscular junction disorder. In the past, the evaluation of the neuromuscular disorders depended on several ways (ex.
- Trial name
- NCT05048862
- Testing
- Neuromuscular ultrasound, Muscle MRI, Nerve conduction studies and autonomic function tests
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Operant Conditioning for Rehabilitation After Stroke
The purposes of this study include: 1. To test if multiple upper extremity muscles represented within a discrete primary motor cortex site reflect existing muscle synergies after stroke. 2.
- Trial name
- NCT05020080
- Testing
- Operant conditioning of motor evoked potentials
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Houston
Healthy
The Effect of Brain Anatomy on the Efficacy of Brain Stimulation Therapy
The purpose of this research study is to determine whether brain anatomy impacts the efficacy of transcranial magnetic stimulation (TMS) which is a form of non-invasive brain stimulation.
- Trial name
- NCT04586387
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University