Clinical trials: sponsored by Brown University
Healthy
Deliver-EE: Evaluating Effects of Meal Delivery
This study will randomly assign 2,300 older adults on waiting lists at fourteen Meals on Wheels programs in Florida, Illinois, Maryland, Tennessee, Texas, North Carolina, South Carolina, and California into two groups who will…
- Trial name
- NCT05357261
- Testing
- Wellness Check and Socialization, Prepared Meals
- Where
- 14 sites in United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV Prevention, HIV Infection Primary
Intervention to Enhance PrEP Persistence
The investigators will conduct a fully powered randomized controlled trial (RCT) to test the effect of a patient navigation intervention on PrEP initiation, adherence and retention in care.
- Trial name
- NCT06872307
- Testing
- RAMP-It-Up Initiation, Adherence, and Retention Intervention
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Brown University
Episodic Memory
The Dynamics of Representational Change Underlying Recall
The goal of this clinical trial is to examine how repeated memory retrieval changes visual representations in the brain in healthy adult participants.
- Trial name
- NCT07442266
- Testing
- Visual Memory Encoding and Retrieval Task During fMRI
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brown University
Prevention
Optimizing PrEP Uptake and Adherence Among Male Sex Workers
"PrEPare for Work" is a randomized controlled trial (RCT) whose goal is to test the efficacy of a behavioral intervention (Short Title: PrEPare for Work) in improving PrEP uptake, adherence, and persistence among male sex workers…
- Trial name
- P4W (NCT05736614)
- Testing
- Stage 1 Strength Based Case Management (SBCM) Condition, Stage 2 PrEPare for Work Intervention Condition
- Where
- 5 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Brown University
Phase I
Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation
The primary aim of this phase I mechanistic pilot study is to evaluate the effects of psilocybin on aspects of cognition in healthy adult volunteers.
- Trial name
- NCT07818564
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Unhealthy Alcohol Use
Supporting Health Through Alcohol Reduction and Relationship Enhancement Together
The aim of this project is to refine the couples-focused intervention with up to 24 adults with unhealthy alcohol use and their partners (N=12 couples) to obtain feedback on the intervention content and structure, as well as the…
- Trial name
- SHARE2Gether (NCT07854756)
- Testing
- SHARE2Gether
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Brown University
Health Behavior, Wellness, Psychological
Teen Health Choices & Wellness
The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older.
- Conditions
- Health Behavior, Wellness, Psychological, Substance Use
- Trial name
- THC&W (NCT06822569)
- Testing
- Cue reactivity paradigm
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Drinking, HIV Viremia
Using Telehealth to Address Alcohol Misuse in HIV Care
This project will test the effects of a telehealth counseling program on reducing alcohol use and improving HIV viral control among people with HIV who drink heavily.
- Trial name
- ReACH3 (NCT04546971)
- Testing
- Brief Intervention, Telehealth Counseling, Text messaging
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Brown University
Physical Inactivity
Comparing Self-paced Versus Moderate Intensity Physical Activity Recommendation for Midlife Adults
We will randomly assign (blocked on Gender (female, male, other), body mass index (BMI; overweight [25 < BMI < 30]) or obese (30 < BMI <40) and pain status (chronic pain vs not)) adults ages 50-64 into either; (a) self-selected…
- Trial name
- NCT05285748
- Testing
- Self-Paced Intensity Physical Activity, Prescribed Moderate Intensity Physical Activity
- Where
- United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Brown University
Iodine Deficiency, Nutrition Poor
Effects of Maternal Multiple Micronutrient Supplementation During Lactation on Child Development in Ethiopia
The goal of this clinical trial is to learn about the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers who live in settings with mild iodine deficiency.
- Conditions
- Iodine Deficiency, Nutrition Poor, Development, Infant, Breastfeeding
- Trial name
- EMECHAT (NCT05901766)
- Testing
- UNIMMAP Multiple Micronutrient Supplement
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brown University
Physical Inactivity
Early Phase Clinical Trial to Test the Feasibility of an ACT-based Physical Activity Promotion Program for Adults With Depressive Symptoms
The goal of the proposed project is to conduct a feasibility clinical trial comparing group-based acceptance and commitment therapy for physical activity, (ACT; ACTivity) to a time- and attention-matched standard PA intervention…
- Trial name
- NCT05407935
- Testing
- ACTivity, Relaxercise
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brown University
Physical Inactivity
Exercise Incentives for YMCA Based Exercise
The investigators will conduct a randomized controlled trial to test financial incentive programs (versus control) to promote physical activity among 330 adults who have a YMCA membership.
- Trial name
- NCT05704712
- Testing
- Monetary Incentives
- Where
- United States
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Brown University
Mixed Fiber Supplementation for Healthy Adults
Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health
This is a randomized, parallel-group interventional study evaluating the short-term gastrointestinal effects of a standardized multi-fiber supplement in healthy adults.
- Trial name
- NCT07787026
- Testing
- Prebiotic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brown University
Inactivity
Web-based Physical Activity Intervention for Latinas
This renewal builds upon our successful culturally adapted PA intervention for Latinas (Pasos Hacia La Salud, R01CA159954) and expands its focus to the critical area of maintenance of behavior change.
- Trial name
- NCT03491592
- Testing
- Enhanced Physical Activity Intervention, Original Physical Activity Intervention
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Brown University
Metabolic Syndrome, Protection Against, Diet, Healthy
Strong Families Start at Home/Familias Fuertes Comienzan en Casa
The goal of this clinical trial is to test the ability of a home-based parental nutrition intervention to improve diet quality in preschool aged children within low-income, Latinx/Hispanic families.
- Trial name
- NCT06099288
- Testing
- Home-Based Video and Motivational Interviewing Intervention, Read Educate and Develop Youth (READY) Comparison
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Brown University
Child Obesity, Nutrition, Healthy
Healthy Start: Family Childcare Providers and Parents
The preschool years are a critical time for shaping food preferences and eating behaviors, which affect dietary behaviors in adults and life-long risks for obesity, diabetes, cardiovascular disease, and other chronic conditions.
- Trial name
- NCT06978270
- Testing
- Healthy Eating: Provider and Parent Components, Healthy Start: Reading Readiness Childcare Proiver and Parent Materials
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Brown University
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections
The proposed study involves conducting a larger-scale study exploring Game Plan's effects among MSM in the real-world, alongside innovative approaches for expanding HIV testing.
- Trial name
- NCT04552171
- Testing
- Access to Game Plan app and 24-hour helpline
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Brown University
Pain, Postoperative, Substance Use
iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery
This is a clinical trial that will evaluate the feasibility and acceptability of a virtual brief program for adolescents and young adults undergoing wisdom tooth extraction and their parents.
- Trial name
- iPAWS (NCT07731295)
- Testing
- iPAWS, Educational Materials
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brown University
Suicide, Suicide Awareness
Hand in Hand, We Rise (Xie Shou Gong Jin)
This study aims to conduct a cluster randomized controlled trial to assess the feasibility of implementing the "Hand in Hand, We Rise" (Xie Shou Gong Jin) multi-stakeholder collaborative school-based suicide prevention program in…
- Conditions
- Suicide, Suicide Awareness, Mental Health, Suicide Prevention
- Trial name
- NCT07722455
- Testing
- Xie Shou Gong Jin, Regular psychoeducation class
- Where
- China
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Brown University