Clinical trials: sponsored by Charite University, Berlin, Germany
Vaccination Knowledge and Acceptance, Informed Vaccine-decision Making
Assessment of Communication Interventions on Vaccination Knowledge and Acceptance
An online randomized controlled trial (RCT) examining the effectiveness of communication measures regarding TBE vaccination in the European context and yellow fever vaccination in the South American context on an informed…
- Trial name
- Y4F WP5/3 (NCT07921121)
- Testing
- Intervention group 1, Intervention group 2, Control format (vaccine check)
- Where
- Germany
- Volunteers
- 1,524 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy
Impact of Propionic Acid on Regulatory T Cell Function in Healthy Adults ( Pro-Health)
Pro-Health is a single-center, double-blind, randomized and placebo-controlled intervention study in healthy adults. The investigators address the effect of a dietary food supplementation of propionic acid on the immune system…
- Trial name
- Pro-Health (NCT06198374)
- Testing
- Sodium propionate
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Postoperative Cognitive Deficit (POCD), Neurocognitive Disorders
International Observational Study on Perioperative Cognitive Trajectories (POCD Census International/PCI)
The purpose of this international, multi-centre observational study is to describe perioperative cognitive changes (pre-existing neurocognitive disorder [NCD], postoperative delirium [POD] and Postoperative Cognitive Dysfunction…
- Trial name
- NCT03540433
- Where
- 3 sites in Germany
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Mental Disorder, Physical Activity
Physical Activity Recommendation Behaviour in German Psychiatrists
The purpose of this study is to examine the physical activity recommendation behaviour, beliefs, barriers and exercise participation in German psychiatrists working with patients with mental disorders.
- Trial name
- NCT04165720
- Testing
- Online questionnaire
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Mental Disorder, Burnout, Caregiver
Professional Quality of Life in German Psychiatrists
The purpose of this study is to assess professional quality of life in German psychiatrists working with patients with mental disorders.
- Conditions
- Mental Disorder, Burnout, Caregiver, Burnout, Professional
- Trial name
- NCT04165733
- Testing
- Online questionnaire
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Sepsis
Development of Context-Adapted Quality Indicators for Early Sepsis Care in Sub-Saharan Africa - A Modified Delphi Consensus Procedure
The research project is an anonymous, prospective, non-interventional consensus study in the form of a modified Delphi method, consisting of three online surveys and structured feedback meetings without recording.
- Trial name
- NCT07711535
- Where
- Ghana
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Burnout Risk
Burnout Intervention During War for Hospital Staff in Ukraine
The project endeavours to investigate the feasibility and acceptability of a psychoeducational training intervention for professional burnout and related psychological variables among both medical and non-medical workers in…
- Trial name
- NCT07620756
- Testing
- Burnout prevention
- Where
- Ukraine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Muscle Atrophy, Myotonia
Electromyostimulation (EMS) of Astronauts in Spaceflight (Easymotion-2)
This is a prospective spaceflight study involving an investigational non-risk device called the EasyMotionSkin for whole body electric muscle (myo) stimulation (WB-EMS) onboard the International Space Station (ISS).
- Conditions
- Muscle Atrophy, Myotonia, Stiffness; Spine, Exercise Overtraining
- Trial name
- Easymotion-2 (NCT06492057)
- Testing
- Electromyostimulation (EMS), Myoton, Electromyography (EMG)
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Incontinence-associated Dermatitis
Prevention of Incontinence-associated Dermatitis
Incontinence-associated dermatitis (IAD) is an inflammation of the skin caused by prolonged direct contact of the skin with urine and/or stool. Elderly and care-dependent people are often affected by this type of inflammation.
- Trial name
- PID (NCT05403762)
- Testing
- ESENTA™ Skin Barrier Spray (ConvaTec, UK), Hydrophobes Basisgel DAC
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Depressive Disorder, Major
Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation
A large body of evidence on depression heterogeneity point to an "immunometabolic" subtype characterized by the clustering of immunometabolic dysregulations with atypical behavioral symptoms related to energy homeostasis.
- Trial name
- MOTIVADE (NCT05909267)
- Testing
- L-dopa/Carbidopa
- Where
- Germany
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
PTSD, Intrusive Memories
Estradiol and Intrusive Memories
The aim of the current project is to investigate the impact of 3mg of oral estradiol valerate on the formation of intrusive memories after analog trauma.
- Conditions
- PTSD, Intrusive Memories, Intrusion Symptom, Trauma
- Trial name
- EstraMemo (NCT07419594)
- Testing
- Estradiol Valerate
- Where
- Germany
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Postoperative Cognitive Dysfunction
Retrospective Evaluation of POCD Data of Studies From KAI, Charité - Universitätsmedizin Berlin
Data on prevention of perioperative neurocognitive disorders (pNCDs) are limited. The purpose of this monocentric parallel - grouped observational registry is to collect study data from studies with pNCDs as primary or secondary…
- Trial name
- NCT02832193
- Where
- 2 sites in Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Palliative Care
Enhancing Palliative Care in ICU
The aim of this study is to reduce the suffering in intensive care through palliative care consultations.
- Trial name
- NCT06605079
- Testing
- Complex intervention, Routine treatment
- Where
- 31 sites in Czechia, Germany and 3 more
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Fall Injury
The Impact of PRISCUS Medication on Fall Risks
Purpose: This study aims to validate the medication entries in the PRISCUS list-a German expert-based compilation of potentially inappropriate medications for older adults-and to identify additional medications that may pose a…
- Trial name
- NCT07181993
- Where
- Germany
- Volunteers
- 932,912 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Vaccination, Immunosenescence
VITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle
The aim of this study is to investigate the effects of a four-week time-restricted eating (TRE) intervention on autophagy, immune function, and vaccine response to a seasonal influenza and COVID-19 vaccines in older healthy…
- Conditions
- Vaccination, Immunosenescence, Metabolism
- Trial name
- VITAL (NCT07000708)
- Testing
- TRE: Time-restricted eating
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Frailty Syndrome
Analysis of Frailty Syndrome Within the Framework of the Innovation Fund Project PRÄP-GO (ANA-PRÄP-GO)
The patients included in PRÄP-GO and the corresponding comparison cohorts will be offered to participate in this complementary study in order to be able to carry out a detailed characterization and phenotyping of the frailty…
- Trial name
- NCT04880824
- Testing
- Prehabilitation- new form of care
- Where
- 27 sites in Germany
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Borderline Personality Disorder (BPD)
Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.
- Trial name
- NCT07091409
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
General Population (no Specific Condition or Disease)
Effects of Forest Therapy on Physical and Psychological Parameters in the General Population - a Randomized Controlled Trial
In recent years, nature and forest therapy has increasingly become the focus of medical research. Recent scientific findings indicate overall positive effects of nature and forest therapy on physical and mental health.
- Trial name
- NCT05562128
- Testing
- Active forest therapy, Passive forest therapy
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Intrusive Memories
The Effect of Dronabinol on the Acquisition and Consolidation of Trauma-Associated Memories
The aim of the current project is to investigate the impact of an activation of the cannabinoid system with an exogenous cannabinoid dronabinol (delta-9-tetrahydrocannabinol) on the formation of intrusive memories after analog…
- Trial name
- NCT04871269
- Testing
- Dronabinol
- Where
- Germany
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Post Traumatic Stress Disorder
Activation of the Endocannabinoid System and Cognition
Recent data suggest that the cannabinoid-system is involved in stress regulation and posttraumatic stress disorder (PTSD). Low endocannabinoid signaling has been found in PTSD patients and might even present a precondition to…
- Trial name
- DronaMemo-2 (NCT05226351)
- Testing
- Dronabinol 2.5 mg
- Where
- 2 sites in Germany
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany