Clinical trials: sponsored by Laval University
Cardiovascular (CV) Risk, Metabolic Health
Advancing Health Equity and Preventive Cardiovascular Care in Indigenous and Remote Communities: a Mobile Healthcare Unit
Indigenous people living in Canada face significant healthcare inequities, particularly in basic, primary, and secondary prevention, leading to higher rates of cardiovascular disease and mortality.
- Conditions
- Cardiovascular (CV) Risk, Metabolic Health, Primary Prevention
- Trial name
- NCT07869069
- Testing
- Cardiovascular risk screening, Follow-up of cardiovascular risk factors
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Laval University
Diet
Identification of Objective Metabolomics-based Biomarkers of Yogurt Consumption
Substantial evidence links yogurt consumption to a lower risk of type 2 diabetes (T2D). However, the existing evidence is derived exclusively from prospective cohort studies relying on self-reported dietary questionnaires…
- Trial name
- YOGBIO (NCT07491887)
- Testing
- Yogurt-free diet, Low-yogurt diet, Moderate-yogurt diet
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Laval University
Digital Health Intervention, Remote Consultation, Teleconsultation
Evaluation and Implementation of Digital Health Ecosystem in Academic Health Center
Mobile health technologies, such as smartwatches, wearable sensors, and digital applications, have the potential to support healthier lifestyles and improve the management of health conditions.
- Conditions
- Digital Health Intervention, Remote Consultation, Teleconsultation, Lifestyle Factors, Stress
- Trial name
- e-IDEA (NCT07831837)
- Testing
- Integrated Digital Health Ecosystem, Usual Primary Care
- Where
- 2 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Gut Microbiota, Metabolic Syndrome
Effect of Raspberry on Gut Microbiota and Metabolic Syndrome
There is growing evidence that nutritional intervention with dietary polyphenols can positively modulate the gut microbiota to improve cardiometabolic health.
- Trial name
- NCT03620617
- Testing
- Raspberry supplement
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Laval University
Gut Microbiota, Metabolic Syndrome
Effects of Blueberry on Gut Microbiota and Metabolic Syndrome
There is growing evidence that nutritional intervention with dietary polyphenols can positively modulate the gut microbiota to improve cardiometabolic health.
- Trial name
- NCT03266055
- Testing
- 50 g of blueberry powder, taken daily for 8 weeks
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Laval University
Cardiovascular Disease
Genes, Omega-3 Fatty Acids and Cardiovascular Disease Risk Factors
The main purpose of this study is to examine whether n-3 PUFA-induced changes in metabolic risk factors are influenced by genetic variations within genes acting as fatty acids sensors.
- Trial name
- FAS (NCT01343342)
- Testing
- n-3 PUFA supplementation
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laval University
Gut Microbiota, Metabolic Syndrome
Effect of Non-nutritive Sweeteners of High Sugar Sweetened Beverages on Metabolic Health and Gut Microbiome
Increasing evidence suggest that artificial sweeteners such as saccharin, aspartame and sucralose may not be as metabolically safe as they first appeared, and it has been proposed that their consumption may be linked to important…
- Trial name
- NCT03259685
- Testing
- 710 ml of regular soft drinks, taken daily for 10 weeks, 710 ml of diet soft drinks, taken daily for 10 weeks, 710 ml of stevia-sweetened soft drinks, taken daily for 10 weeks
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Laval University
Abdominal Obesity
Effects of a Polyphenol-rich Cranberry Extract on Cardiometabolic and Neurocognitive Health
The objective of this double-blind, parallel, randomized placebo-controlled clinical trial is to evaluate the effects of consumption of polyphenol-rich cranberry extract standardized in PACs (36 mg PACs/capsule) on…
- Trial name
- Neurocan (NCT05062954)
- Testing
- Polyphenol-rich cranberry extract supplement standardized in proanthocyanidins
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Laval University
Body Composition Changes, Body Weight Change
Effect of Dairy Protein Yogourt vs Plant-based Yogourt on Body Weight, Body Composition, Bone Health and Gut Microbiota
The consumption of an adequate quantity of protein in the diet is essential to maintain a healthy body composition and functioning.
- Conditions
- Body Composition Changes, Body Weight Change, Metabolic Health, Bone Metabolism
- Trial name
- PROYO (NCT07578103)
- Testing
- Dairy yogurt, Plant based yogurt, No yogurt
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Laval University
Overweight/Obesity, Metabolic Syndrome
Effects of Cranberry on Gut and Metabolic Health
The consumption of plant-based foods, particularly berries, has been associated with improved health due to their high content of bioactive compounds.
- Conditions
- Overweight/Obesity, Metabolic Syndrome, Insulin Resistance, Microbiota
- Trial name
- CRANOS (NCT07460856)
- Testing
- Cranberry beverage
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Laval University
Healthy Eating
Eating Fruits and Vegetables With Pleasure!
The objective of this interventional study is to pilot test a newly evidence-based intervention integrating different dimensions of eating pleasure to promote the consumption of fruits et vegetables.
- Trial name
- PLAISIR (NCT07387289)
- Testing
- Eating fruits and vegetables with pleasure!
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Laval University
Hepatitis B
Immunogenicity of 2 Versus 3 Doses of Combined Hepatitis B Vaccines in 2-18 Months Old Children
The main objective of this study is to compare the immunogenicity of the hepatitis B component in children vaccinated with (I) two doses of Infanrix-hexa administered at 2 and 12 months of age versus (II) one dose of…
- Trial name
- NCT04294433
- Testing
- Infanrix-hexa, Infanrix-hexa and Twinrix Junior
- Where
- 2 sites in Canada
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- Laval University
Insomnia Disorder, Insomnia
Cultural Adaptation of CBTi for the Arab World
The goal of this clinical trial is to learn whether culturally adapted versions of Cognitive Behavioral Therapy for insomnia (CBTi) can reduce insomnia severity and improve sleep and mood outcomes in Arab adults with insomnia.
- Conditions
- Insomnia Disorder, Insomnia, Cultural Adaptation
- Trial name
- NCT07337369
- Testing
- Surface+deep level adaptations, Surface level adaptation
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Laval University
Employee Well-being, Work-related Outcomes
Effectiveness of a Multi-Modal Workplace Rest Cabin on Worker Well-Being
This study examines whether access to a rest cabin in the workplace supports employee well-being. Employees of a Canadian insurance company are randomly assigned to one of two groups: immediate access to the rest cabin or a…
- Trial name
- RECHARJME-RCT (NCT07322354)
- Testing
- Recharjme Multi-Modal Rest Cabin
- Where
- 4 sites in Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Laval University
Diabetes, Mellitus, Type 1
A Study About Patient Decision Aids Designed to Help Parents and Guardians in Canada Make Evidence-informed, Values-congruent Decisions About Screening Children for Type 1 Diabetes and Follow-up Decisions.
This study will design and test patient decision aids to help parents and guardians in Canada make decisions about screening their children for type 1 diabetes.
- Trial name
- NCT07317973
- Testing
- Web-based patient decision aid, Standard materials
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Laval University
Type 1 Diabetes (T1D)
CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada
When you live with type 1 diabetes (T1D), it is easy to feel alone. Managing your own T1D or your child's T1D takes constant effort that is invisible to most people.
- Trial name
- NCT07317986
- Testing
- Peer support meetings
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Laval University
Gut Epithelial Permeability, Gut Microbiota Composition and Diversity
Impact of Dairy Integration Into Canadian Food Guide on Gut Health
The primary objective is to investigate the impact of milk, fermented milk, and soy beverages, incorporated in a diet reflecting adherence to Canadian food guide recommendations on food choices on gut microbiota in middle-aged…
- Conditions
- Gut Epithelial Permeability, Gut Microbiota Composition and Diversity, Gut and Circulating Inflammatory Markers, Milk and Digestion
- Trial name
- GutMilk (NCT07257913)
- Testing
- Milk, Fermented milk, Soy beverage
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Wheelchairs
Wheelchair Skills Training for Children and Youth
Manual wheelchair (MWC) skills training is a critical component of wheelchair service provision. However, children and youth receive little to no training.
- Trial name
- NCT05564247
- Testing
- Wheelchair Skills Training Program (WSTP)
- Where
- 3 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Intestinal Permeability
Establishing and Validating a Meal-provoked Intestinal Permeability Test for Nutritional and Metabolic Health Clinical Research.
Development of Intestinal Permeability Tests for Clinical Nutrition and Metabolic Health Studies
- Trial name
- Gut-Perm (NCT07066176)
- Testing
- Aspirin, Mixed meal beverage
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laval University
Familial Hypercholesterolemia, Nutrition, Healthy
Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia.
The investigators will first conduct a fully controlled dietary randomized crossover trial (RCT) including 50 adults with HeFH to investigate the impact of a whole food plant-based (WFPB) diet low in red and processed meats and…
- Conditions
- Familial Hypercholesterolemia, Nutrition, Healthy, Cholesterol, Elevated, Cholesterol; Metabolic Disorder
- Trial name
- FH-Diet (NCT05181553)
- Testing
- Whole-food plant based diet (WFPB diet), Standard North American diet (SAD diet)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laval University