Clinical trials: sponsored by Oregon Health and Science University
Cardiovascular Risk Factor, Circadian Dysregulation
Body Weight, Sleep, and Heart Health
A multidisciplinary investigation examining the circadian mechanisms regulating cardiovascular (CV) risk, with an additional focus on obesity.
- Conditions
- Cardiovascular Risk Factor, Circadian Dysregulation, Obesity
- Trial name
- NCT03388788
- Testing
- Positron Emission Tomography (PET) scanning of cardiac function at 3 time points across the 24 hour circadian cycle
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity
Evaluation of Safety and Health Involvement For Truck Drivers
The current project is a randomized, controlled evaluation of a new weight loss and health promotion intervention for truck drivers.
- Trial name
- SHIFT (NCT02105571)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain Catastrophizing, Pain, Chronic
Efficacy of a Chronic Pain Treatment Prior to Gender-affirming Surgery
The primary objective of this study is to examine a single-session, 2-hour group intervention provided to a population of transgender or gender-diverse patients with chronic pain prior to gender-affirming surgery, to determine if…
- Conditions
- Pain Catastrophizing, Pain, Chronic, Gender Identity
- Trial name
- NCT06443164
- Testing
- Empowered Relief, Standard of Care
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Nonspecific Chronic Low Back Pain
Body and the Brain: Cortical Reactivity and Cognitive-Affective Regulation to Experimental Pain.
The purpose of this cross-sectional study is to compare cortical reactivity and cognitive-affective regulation in response to experimental pain between healthy controls and individuals with non-specific chronic low back pain.
- Trial name
- NCT07896785
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep
Cannabis Association With Sleep Study
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
- Trial name
- CaSS (NCT06982950)
- Testing
- Manipulation of Sleep Duration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Distress, Emotional, Internalizing Mental Health Symptoms
Piloting a School-Based Distress Tolerance Skills Program for Adolescents
Research suggests that an individual's perceived ability to withstand distressing or upsetting emotions (i.e., distress tolerance; DT) is a common risk factor across several mental health conditions that commonly emerge during…
- Trial name
- STRIDE (NCT06638853)
- Testing
- Distress Tolerance Skills Training
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diet, High-Fat, Circadian Rhythm
Food and Circadian Timing
The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to…
- Trial name
- FACT (NCT04743271)
- Testing
- High-Fat Diet, Low-Fat Diet
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
School Readiness, Preschool Enrollment
A Kinder Coaching Program With Community Health Workers "READY"
In this study, the investigators compare two novel primary care interventions (School Readiness Checklist vs. Kinder Coaching) for low-income parents, which were co-developed by parent, clinical, and educational stakeholders.
- Conditions
- School Readiness, Preschool Enrollment, Parent School Readiness Confidence
- Trial name
- READY (NCT07677618)
- Testing
- Kinder Coaching
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Infertility of Tubal Origin
Clinical Evaluation of a Tubal Selective Delivery System
A single center study to evaluate the performance and optimize the design of a novel intrauterine catheter system intended as a nonsignificant risk medical device to aid in evaluating tubal patency as part of the initial…
- Trial name
- NCT05775913
- Testing
- Tubal Selective Delivery System (TSDS)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Endometrial Biopsy in Progestin Contraceptive Users
The purpose of the study is to learn more about menstrual changes in progestin contraception users. The investigators are hoping to find out what changes in the endometrium lead to different bleeding patterns during the first…
- Trial name
- NCT05760144
- Testing
- DMPA, Etonogestrel implant
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Glaucoma
Functional and Structural Imaging for Glaucoma
The specific aims of the clinical studies are to: Develop a directional high-resolution OCT and OCT angiography prototype to improve imaging of structure and perfusion.
- Trial name
- FSOCT (NCT01957267)
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep, Cardiovascular Risk Factor
Sleep Duration and Cardiovascular Health
This is a cross-sectional study with an optional intervention that will examine how extreme sleep durations relate to cardiovascular health, physical activity, and sleep quality by studying three groups of participants: short…
- Trial name
- Goldilocks (NCT04804124)
- Testing
- Regularized Sleep Schedule
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypertension, Cardiovascular Risk Factor
Sleep and Circadian Mechanisms of Non-dipping Blood Pressure
This study will be the first to distinguish the relative contributions of sleep, circadian and behavioral mechanisms to the non-dipping BP profile in Black adults and will lay the groundwork for optimizing therapies dependent on…
- Trial name
- NCT03558893
- Testing
- Forced Desynchrony
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraceptive Usage
Disparities in Emergency Contraceptive Metabolism Dictate Efficacy
The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not.
- Trial name
- NCT05674513
- Testing
- Ulipristal acetate
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cardiovascular Disease (CVD) Risk Factors
Empowering Cardiovascular Health in Custodial Grandparents
In this study, the investigators will tailor an existing intervention (Rural Caregiver Heart Health Education (RICHH)) protocol and test its feasibility, acceptability, and initial effect with grandparent caregivers.
- Trial name
- ECG (NCT07083895)
- Testing
- Modified RICHH, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy
Providing Birth Control Through Home Health Visits
This study will evaluate a program that provides birth control to low income and minority women through home visits by a community health nurse. The goal of the program is to reduce unwanted pregnancies.
- Trial name
- NCT00065078
- Testing
- Home dispensing of contraception, Family Planning Counseling
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
IUD
IUD Self-Removal Study
This is a pilot study designed to test the effectiveness of several techniques for intrauterine device (IUD) self-removal and to understand patient preferences regarding IUD self-removal and indicators of success as well as…
- Trial name
- NCT05339555
- Testing
- Instructions for IUD Self-Removal Provided to Participant
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Healthy, Aging
Ashwagandha Pharmacokinetics Study in Older Adults
This study will measure the oral bioavailability and pharmacokinetics of known compounds from a standardized Withania somnifera botanical dietary supplement in healthy older adults.
- Trial name
- NCT06171724
- Testing
- Shoden
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep
Assessing Construction Execution Under Sleep Impairment
The goal of this study is to learn whether virtual reality (VR) construction tasks can detect performance changes associated with prior sleep, and to determine the extent to which these changes can be distinguished from…
- Trial name
- ACES (NCT07431970)
- Testing
- Construction Virtual Reality Stress Challenges, No Construction Virtual Reality Stress Challenges
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep, THC
Tetrahydrocannabinol (THC) and Sleep
The investigators will test the effects of 10-60mg dronabinol (oral THC) on sleep in non-frequent and frequent cannabis users.
- Conditions
- Sleep, THC, Marijuana, Cannabis
- Trial name
- NCT03560934
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University