Clinical trials: sponsored by Penn State University
Emotional Well-being, Psychological Stress
Feasibility of a Mind-Body Intervention for Optimism
This pilot study tests whether three brief mind-body activities can be delivered remotely to midlife adults, and whether they show early signs of improving cardiovascular health, emotional well-being, and stress.
- Conditions
- Emotional Well-being, Psychological Stress, Cardiovascular Risk
- Trial name
- NCT07862478
- Testing
- Emotional Well-Being Writing, Chair-Assisted Squats, Slow-Paced Breathing
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Diet Quality, Sleep
The Effects of an Evening Snack of Walnuts on Diet and Sleep Quality in Adolescents
The goal of this study is to examine whether an evening snack of 1 oz of walnuts consumed in place of usual evening snacks for 4 weeks has a beneficial effect on diet quality and sleep quality in adolescents age 13-17 years.
- Trial name
- NCT07862556
- Testing
- Walnuts, Control (usual diet)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Penn State University
COVID-19 Vaccination
Influence of Vaccine Message Medium on Intentions to Vaccinate in College Students
The goal of this clinical trial is to understand the influence of vaccine message medium (e.g., text, photo, or video) on intentions to vaccinate in college students.
- Trial name
- NCT07861087
- Testing
- COVID-19 Video, COVID-19 Words, COVID-19 Poster
- Where
- United States
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular (CV) Risk
Lions Hearts: A Community Approach to Multigenerational Cardiovascular Disease Risk
This pilot study evaluates the feasibility, acceptability, and preliminary effectiveness of Lion Hearts, a community-based, family-centered physical activity intervention designed to improve cardiovascular health among…
- Trial name
- NCT07147387
- Testing
- Lion Hearts Family-Based Physical Activity Program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University
Menopause, Aging
Role of Menopause in Thermoregulation
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events.
- Trial name
- NCT06798571
- Testing
- Elagolix Oral Tablet, Estradiol patch
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Penn State University
Weight Gain Trajectory, BMI
Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists
This study looks at whether using secure digital systems to share information between pediatric health care providers (during regular well-child visits) and social care providers (during regular visits with WIC nutritionists) can…
- Conditions
- Weight Gain Trajectory, BMI, Responsive Parenting, Diet Quality
- Trial name
- WEE Baby (NCT07494097)
- Testing
- Data integration around responsive parenting, Standard Care (in control arm)
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Penn State University
Chronic Stress, Anxiety
Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program
The goal of this clinical trial is to the efficacy of the Building a Strong Identity and Coping Skills intervention within a sample of low-income and minoritized youth aged 11-14 who are seeking mental health treatment and have…
- Conditions
- Chronic Stress, Anxiety, Depression
- Trial name
- NCT05789446
- Testing
- Building a Strong Identity and Coping Skills
- Where
- 5 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiovascular Diseases
Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs
This study will examine the effect of a healthy diet containing 2 eggs per day compared to a healthy diet containing 3 eggs per week on biomarkers of heart health after 4 weeks.
- Trial name
- NCT06120400
- Testing
- Whole Egg
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Penn State University
Vegetable Acceptance in Early Childhood, Vegetable Intake
Evaluating the Implementation and Impact of an Enhanced SNAP-Ed Delivered Curriculum in Low-income Preschools
This evaluation project aims to assess the impact of the Penn State Child Health Research Center's final year of SNAP-Ed funded nutrition education program in low-income preschool classrooms in Pennsylvania.
- Conditions
- Vegetable Acceptance in Early Childhood, Vegetable Intake, Knowledge
- Trial name
- NCT07366437
- Testing
- Rainbow Veggie Club
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University
Childhood Obesity
PROGRESS for the Primary Prevention of Early Overweight in Low-income, Rural Families
The Parent Responsiveness Optimized: Growth, Regulation, Eating, Sleep, and Soothing (PROGRESS) study is a randomized clinical trial designed to prevent early childhood overweight among rural, low-income families participating in…
- Trial name
- PROGRESS (NCT07823582)
- Testing
- Sleep-Soothe-Play Responsive Parenting, Parent-Child Communication, Parental Mindfulness
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Childhood
Resilience to the Effects of Advertising in Children
Strong empirical evidence shows food marketing promotes excess energy intake and obesity. Yet, not all children are susceptible to its effects and this variability is poorly understood.
- Trial name
- REACH (NCT05073185)
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy Aging, Middle-aged and Older Adults
Peanut Butter and Brain Health
Healthy foods, including peanuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Trial name
- NCT07774546
- Testing
- Peanut butter
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Penn State University
Parenting, Parent-Child Relations
Promoting Co-Parenting and Reducing Hazardous Drinking in New Families
This study aims to understand if a parenting program that helps couples learn to parent as a team and maintain a healthy lifestyle, such as maintaining safer levels of alcohol use, promotes parent and child health and well-being.
- Conditions
- Parenting, Parent-Child Relations, Drinking, Alcohol, Adjustment
- Trial name
- NCT04441307
- Testing
- Healthy Foundations, Family Foundations
- Where
- 2 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Penn State University
Amyotrophic Lateral Sclerosis
Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications
The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers.
- Trial name
- NCT06266403
- Testing
- Structured Communicative Interaction, Clear Speech, Unstructured communicative interaction
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Penn State University
Endometriosis
Endometriosis and Microvascular Dysfunction: Role of Inflammation
The purpose of this study is to better understand the underlying mechanisms associated with elevated cardiovascular disease risk in women with endometriosis, and to measure the effectiveness of emerging endometriosis treatments…
- Trial name
- Endo3/SA2 (NCT05069740)
- Testing
- Salsalate Pill
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Penn State University
Endometriosis
Thromboxane Function in Women With Endometriosis
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: Do women with endometriosis have greater blood pressure and pain…
- Trial name
- NCT05962034
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Penn State University
Aging
Transient Receptor Potential Channels
Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili…
- Trial name
- TRP (NCT06444594)
- Testing
- TRPM8 Agonist, TRPV1 Agonist, TRPV4 Agonist
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Penn State University
Underage Drinking, Cannabis Use
Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use
College students' risky drinking and cannabis use are major public health problems. The harms associated with risky drinking have been well-documented (such as deaths, blackouts, injuries, assaults, arrests, sexual consequences…
- Conditions
- Underage Drinking, Cannabis Use, Drinking, Teen, Drinking, College
- Trial name
- NCT05345951
- Testing
- e-PBI+, e-PBI
- Where
- United States
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- Penn State University
Antimicrobial Resistance
Optimizing Antibiotics Prescription
Interventions that are low-cost, do not add substantially to the physician workload, are consistent with good physician practices and WHO guidelines, and serve as a reminder on the risks of overprescribing antibiotics are…
- Trial name
- NCT06436690
- Testing
- Diagnosis Mandate, Individualized Feedback
- Where
- 2 sites in United States, Nepal
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Penn State University
Upper Resp Tract Infection
Community Interventions for Tackling Antimicrobial Resistance in Ghana
This research project aims to test the effect of two interventions targeted to community pharmacies in the Greater Accra region, Ghana, on antibiotics dispensing rates.
- Trial name
- CITAR-Ghana (NCT07284914)
- Testing
- Individualized Feedback, Legal Reminder
- Where
- Ghana
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Penn State University