Clinical trials: sponsored by University of Calgary
Colorectal Cancer
I-Scan Versus High-definition White Light
The purpose of the study is to assess whether the use of I-scan during colonoscopy leads to an increased yield of adenomas in the colon among a population at increased risk for CRC.
- Trial name
- NCT01617278
- Testing
- I-Scan 1, HD Colon, I-Scan 2
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pulmonary Embolism, Diagnostic Uncertainty
The Visualization of Uncertainty in Clinical Diagnostic Reasoning for Pulmonary Embolism
Medical reasoning is a form of inquiry that examines the thought processes involved in making medical decisions. When physicians are faced with patients' symptoms or signs, their thought processes follow either direct shortcuts…
- Conditions
- Pulmonary Embolism, Diagnostic Uncertainty, Clinical Reasoning, Evidence Based Medicine
- Trial name
- NCT01752673
- Testing
- Visualized pulmonary embolism computer task model, Didactic review lecture
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colonoscopy Preparation
Single Dose Versus Split Dose Polyethylene Glycol-based Colonic Lavage for Colonoscopy
Proper bowel cleansing prior is an essential requirement for the conduct of colonoscopy. However, due to the nature of cleansing process, the ideal bowel cleansing preparation remains elusive.
- Trial name
- NCT01610856
- Testing
- Polyethylene Glycol
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Cancer
Split Dose Polyethylene Glycol (PEG) + Clear Fluids Versus Split Dose PEG + Low-Residue Diet
The objective of the study is to examine the effect of adding a strict low-residue lunch on the day before colonoscopy has on clinical efficacy and patient tolerability of bowel preparation, with patients receiving split-dose…
- Trial name
- BP (NCT01610895)
- Testing
- Split-dose PEG Based Lavage (2L + 2L) with Low-Fibre Lunch Dietary instructions, Split-dose PEG Based Lavage (2L + 2L) with Standard Dietary Instructions
- Where
- Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bowel Preparation for Colonoscopy
Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
The objective of this study is to compare the efficacy, safety and tolerability of two bowel preparations for colonoscopy - split dose Polyethylene Glycol-Based Lavage and Pico-Salax plus Bisacodyl - with a specific emphasis on…
- Trial name
- BP (NCT01415687)
- Testing
- Polyethylene Glycol-Based Lavage, Pico-Salax (Magnesium Citrate) plus Bisacodyl
- Where
- 2 sites in Canada
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Children's Distress During Flu Vaccination
Reducing Children's Distress Towards Flu Vaccinations
Millions of children in North America receive an annual flu vaccination, many of whom are at risk of experiencing severe distress. Children frequently use technologically advanced devices such as computers and cell phones.
- Trial name
- NCT01529021
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Vascular Diseases, Myocardial Ischemia
Assessment of Oxygen Changes in the Heart With Cardio-vascular Magnetic Resonance Imaging
The ability of a new SSFP-based BOLD MRI sequence to assess myocardial oxygenation changes in response to coronary flow changes induced by adenosine and increased CO2-partial pressure will be examined in healthy volunteers and…
- Trial name
- NCT00693758
- Testing
- adenosine, modified end-tidal forcing system, arm cuff occlusion
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Ventricular Function, Left
Assessment of Cardiac Involvement of Common Cold in High Performing Athletes by Cardiac Magnetic Resonance Imaging (MRI)
Cardiovascular magnetic resonance (CMR) imaging will be used to assess the impact of common colds and physical training in high-performing athletes. Healthy individuals from the general public will serve as a comparison group.
- Trial name
- NCT00739895
- Testing
- Cardiac magnetic Resonance study, Blood testing
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Endothelial Function
Endothelial Function Assessed With BOLD-MRI
The purpose of this study is to assess the applicability of a new SSFP-based BOLD sensitive MRI sequence in evaluating endothelial function. Endothelial function will be tested in a setting of reactive hyperemia in the forearm.
- Trial name
- EFBOLD-MRI (NCT00575120)
- Testing
- ischemia reperfusion
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Diabetes Mellitus
Diabetes Exercise and Lifestyle Trial
The objective of this study is to determine the effects of supervised combined aerobic and resistance training, and the effects of stage-matched written materials delivered by mail or internet, alone or in combination, on…
- Trial name
- DEAL (NCT00877864)
- Testing
- High volume combined aerobic/resistance exercise, Low volume combined aerobic/resistance exercise, High volume combined A/R exercise, printouts, pedometers
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Stress
Does a Portable Biofeedback Tool Reduce Physician Stress?
Given the nature of their work duties and work environment, physicians often experience stress within the workplace and chronic stress negatively impacts physician wellness.
- Trial name
- NCT01067183
- Testing
- portable biofeedback tool and relaxation breathing technique
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cardiovascular Diseases, Hypertension
U-CHAMP: Urban Cardiovascular Health Assessment and Management Program
High blood pressure, elevated blood glucose and high cholesterol are related to the increased risk of stroke and heart disease. Many studies have shown that this risk can be significantly reduced by lowering blood pressure, blood…
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia, Hyperglycemia
- Trial name
- U-CHAMP (NCT00626041)
- Testing
- participant referral to primary care network physician
- Where
- 2 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Calgary
ACL Reconstruction
Home Vs. Physiotherapy Supervised Rehabilitation After ACL Reconstruction
This study was designed to determine whether or not there were any differences in knee range of motion, both statically and during gait, sagittal plane knee laxity, and quadriceps and hamstrings strength in patients three months…
- Trial name
- NCT00564837
- Testing
- Home-based rehabilitation program, Physiotherapy-supervised rehabilitation program
- Where
- Canada
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Chronic Sinonasal Symptoms
The Use of Oral N-Acetyl Cysteine for the Treatment of Chronic Sinonasal Symptoms
Chronic sinonasal symptoms (CSNS), such as coughing, throat clearing, nasal obstruction, crusting, dryness and discharge are extremely common in the general population.
- Trial name
- NCT00866866
- Testing
- N-Acetyl Cysteine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Achilles Tendinopathy, Achilles Tendon Enthesopathy
Treatment for Achilles Tendinopathy
The purpose of this study is to determine whether sclerotherapy using a 25% dextrose and 1% lidocaine solution is an efficacious treatment for patients with chronic Achilles tendinopathy who have failed a home based, heavy load…
- Conditions
- Achilles Tendinopathy, Achilles Tendon Enthesopathy, Mid-Portion Achilles Tendinopathy, Insertional Achilles Tendinopathy
- Trial name
- NCT00835939
- Testing
- 25% Dextrose and 1% Lidocaine, Lidocaine, sclerotherapy
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity
Prebiotic Fiber as a Modifier of Satiety Hormones and Body Weight in Overweight and Obese Adults
The purpose of this study is to determine if oligofructose supplementation promotes weight loss in overweight and obese adults.
- Trial name
- NCT00522353
- Testing
- Oligofructose
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cardiovascular Diseases, Hypertension
ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups.
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia
- Trial name
- ICA-CHAMP (NCT00627159)
- Testing
- High risk assessment, Low to moderate risk
- Where
- 2 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Calgary