Clinical trials: sponsored by Xijing Hospital
Gastrointestinal Cancers
A Multicenter Prospective Observational Cohort Study for Digestive Tract Tumor Screening Using Multi-Target Blood and Fecal Biomarkers
This project aims to evaluate the sensitivity and specificity of combined blood multi-gene methylation and fecal biomarkers for pan-digestive tract cancer screening, so as to establish a novel technical system for the early…
- Trial name
- NCT07769892
- Where
- 7 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Colorectal Adenoma, Colorectal Polyps
Advanced Adenoma Detection With 3D Imaging Device During Colonoscopy
The goal of this clinical trial is to learn if 3-dimensional (3D) imaging device works to identify patients with high risk adenomas during colonoscopy to guide proper follow-up strategy.
- Trial name
- NCT06924489
- Testing
- Colonoscopy after bowel cleansing with 2D imaging device, Colonoscopy after bowel cleansing with 3D imaging device
- Where
- China
- Volunteers
- 1,566 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastrointestinal Tumors
A Study on Gastrointestinal Cancer Screening Using a Multi-Targeted Combined Detection Model
This study is a multicenter, randomized controlled trial. The plan is to enroll eligible participants and randomly assign them to two groups: one group will undergo testing using a combined model of "multi-target blood…
- Trial name
- NCT07712107
- Testing
- Multi-target blood methylation + fecal FIT + fecal calprotectin
- Where
- 6 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Gastric Cancer, Colorectal Cancer
Evaluation of Fecal Multi-target Biomarkers in the Screening of Digestive Tract Cancers
This study is a multi-center, observational study. Participants scheduled for gastroscopy and colonoscopy will undergo an epidemiological assessment and provide a stool sample prior to endoscopy for qualitative Fecal…
- Trial name
- NCT07600125
- Testing
- Qualitative Fecal Immunochemical Test (FIT), quantitative (FIT), and testing for new biomarkers
- Where
- 13 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Oliceridine Fumarate
Effect of Postoperative Analgesia of Oliceridine Fumarate for Gastrointestinal Function Recovery in Patients Undergoing Lumbar Spine Surgery
Osemitidine fumarate is a novel G protein-biased ligand μ-opioid receptor agonist. Previous studies have confirmed its potent analgesic effects and safety: compared with morphine, it reduces respiratory depression and…
- Trial name
- NCT07307495
- Testing
- Sufentanil, Oiceridine
- Where
- China
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Post Traumatic Stress Disorder, Postoperative Complications
PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients
The objective of this prospective cohort study is to explore the association between the development of post-traumatic stress disorder (PTSD) in surgeons and anesthesiologists and postoperative prognosis in surgical patients they…
- Conditions
- Post Traumatic Stress Disorder, Postoperative Complications, COVID-19
- Trial name
- NCT05732116
- Testing
- PTSD
- Where
- 2 sites in China
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Epilepsy, Psychogenic Non-epileptic Seizures
Study on the Rapid Diagnostic Value of Sudden Clap Provocation Test in Psychogenic Nonepileptic Seizures
To explore the clinical value of the sudden clap provocation test in the differential diagnosis between epileptic seizures and psychogenic non-epileptic seizures, so as to provide a new strategy for rapid, low-cost differential…
- Trial name
- PNES ACPT (NCT07742709)
- Testing
- Abrupt Clap Provocation Test
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Prostate Cancer
Plasma Exosome RNA to Diagnose Prostate Cancer
The aim of the present study is to investigate a RNA combination to diagnose prostate cancer.
- Trial name
- exo-PRECISE (NCT06604130)
- Testing
- Prostate cancer screening decision
- Where
- 9 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Narcolepsy Type 1 (NT 1), Hypersomnolence Disorder
Radar Sleep Monitoring in Type 1 Narcolepsy: Feasibility
This study aims to evaluate the clinical feasibility of a millimeter-wave radar sleep monitoring system in the diagnosis of Narcolepsy Type 1 (NT1).
- Trial name
- NCT07654803
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Kidney Stone
Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones
Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.
- Trial name
- NCT07350369
- Testing
- Detect the levels of metabolites in blood and urine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Colitis, Ulcerative, Sleep Quality
Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis
Ulcerative colitis(UC) is one of the two main forms of inflammatory bowel disease(IBD), which seriously affects the quality of life of patients.
- Conditions
- Colitis, Ulcerative, Sleep Quality, Gastrointestinal Microbiome, Autonomic Nervous System Imbalance
- Trial name
- NCT06359808
- Where
- China
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Vitiligo
Building an Assessment Model for Vitiligo Activity and Prognosis Using Peripheral Blood Cytokine Profiles
Vitiligo is a chronic autoimmune disorder characterized by depigmented patches on the skin, which can pose significant psychosocial challenges, particularly for individuals with darker skin tones.
- Trial name
- NCT07298551
- Testing
- Serum Cytokine Assay
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Heat Stroke, Early Waking
Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke
Heat stroke is a clinical syndrome with high incidence and high fatality rate in summer. Patients with liver, kidney, and brain damage are prone to secondary MODS, and the prognosis is poor due to high medical costs.
- Conditions
- Heat Stroke, Early Waking, MODS, Proteinosis
- Trial name
- NCT05155358
- Testing
- Peripheral blood test
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Melanoma (Skin Cancer), Health Volunteers
Study of Melanoma-Resistant PET Monitoring Based on Key Rate-limiting Enzymes for Fatty Acid Metabolism in Healthy Volunteers
This is a small-sample safety study involving 15 healthy volunteers who were divided into groups and underwent 68Ga-ACC-DE, 68Ga-FASN-DE, and 68Ga-ACLY-DE PET/CT imaging for safety, biodistribution, and radiation dosimetry…
- Conditions
- Melanoma (Skin Cancer), Health Volunteers, PET / CT
- Trial name
- NCT07114172
- Testing
- 68Ga-ACC-DE/68Ga-FASN-DE/68Ga-ACLY-DE PET/CT
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Alzheimer Disease (AD), Cognitive Dysfunction, Cognitive Disorder
Aβ PET and Tau PET Imaging in the Diagnosis and Progression Assessment of Alzheimer's Disease
This prospective study recruited 20 healthy volunteers and 50 patients diagnosed with Alzheimer's disease (AD) and mild cognitive impairment (MCI) according to clinical guidelines.
- Conditions
- Alzheimer Disease (AD), Cognitive Dysfunction, Cognitive Disorder, PET Imaging
- Trial name
- NCT07114224
- Testing
- AV45/AV-1、AV1451 PET
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Constipation - Functional, Refractory Constipation
Predicting Treatment Outcomes in Refractory Constipation Through Brain Connectivity Evaluation
The goal of this observational study is to identify the characteristics of brain functional connectivity in refractory constipation and fluoxetine-sensitive patients.
- Conditions
- Constipation - Functional, Refractory Constipation, Fluoxetine, fMRI
- Trial name
- NCT06221722
- Testing
- BOLD-fMRI, Regular treatment of functional constipation, fluoxetine
- Where
- 3 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study was to evaluate the efficacy and safety of the triple therapy of berberine hydrochloride, vonorasan and amoxicillin for the primary eradication of Helicobacter pylori.It is hypothesized that berberine…
- Trial name
- NCT06514274
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori
Effect of Oral Helicobacter Pylori Infection on the Efficacy of Gastroluminal Helicobacter Pylori Eradication Therapy
The aim of this study is to assess the effect of oral Helicobacter pylori infection on the efficacy of gastric Helicobacter pylori infection eradication.
- Trial name
- NCT05790525
- Testing
- Standard bismuth quadruple
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Non-suicidal Self-injury (NSSI), Adolescent
Clinical and Psychosocial Characteristics of Adolescent Patients With Non-Suicidal Self-Injury
The overall objective of this study is to explore the social and clinical psychological characteristics of adolescents with depression accompanied or not accompanied by non-suicidal self-harm. This is an observational study.
- Conditions
- Non-suicidal Self-injury (NSSI), Adolescent, Depression
- Trial name
- NCT06885749
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Premature Ejaculation
Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial
This is a controlled study of patients with and without primary premature ejaculation. It is based on near-infrared spectroscopy (NIRS) functional brain imaging to detect and compare changes in brain activity in resting and task…
- Trial name
- NCT06570135
- Testing
- Detecting Brain Activity with Functional Near Infrared Spectroscopy
- Where
- 2 sites in China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital