Clinical trials: enrolling by invitation
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Parkinson's Disease
Effect on Parkinson's Disease After Therapeutic Induction of CranioSacral Integrated Therapy
We are studying \& researching the effect of CranioSacral Integrative therapy on Parkinson's Diseased Patients for 3 months. With a therapeutic induction via manual CranioSacral integrative therapy for 90 minutes per session with…
- Trial name
- NCT01989013
- Testing
- biweekly intervention
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Zia, Al Raza
Childhood Obesity
Respiratory Effects of Obesity in Children: Longitudinal Consequences After 6 Years of Aging
The purpose of the study is to re-examine body composition, respiratory function, exercise tolerance, and dyspnea on exertion (DOE) in children with obesity (CWO) and children without obesity (CWOO) who were originally studied as…
- Trial name
- NCT06447246
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Heart Failure With Preserved Ejection Fraction (HFPEF)
The Effect of Adiposity on Muscle and Microvascular Function in HFpEF
This project is an observational study in patients with heart failure with preserved ejection fraction (HFpEF) who are candidates for treatment with weight loss medication to manage obesity or diabetes as part of their standard…
- Trial name
- NCT06930495
- Testing
- Weight loss SOC Treatment with second generation anti-diabetic medications
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
PreDiabetes, Lifestyle, Healthy
Study of a Diabetes Prevention Patient Activation Clinical Decision Support Tool
The investigators overarching goal is to increase the percentage of patients engaging in diabetes prevention activities to reduce the incidence of diabetes.
- Conditions
- PreDiabetes, Lifestyle, Healthy, Activation, Patient
- Trial name
- NCT06358261
- Testing
- Diabetes Prevention Patient Activation Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Traumatic Brain Injury
Imaging of Traumatic Brain Injury Metabolism Using Hyperpolarized Carbon-13 Pyruvate
This project is to evaluate sensitivity and specificity of hyperpolarized 13C-pyruvate as imaging agents of altered cerebral glycolysis and mitochondrial dysfunction and assess pyruvate utilization in mitochondria in Traumatic…
- Trial name
- HPTBI (NCT03502967)
- Testing
- Hyperpolarized [1-13C] Pyruvate, Hyperpolarized [2-13C] Pyruvate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Parenting Intervention
A Strength-based Parenting Program for Parents With Young Children From 3 to 6 Years Old
The parent education and family support component in phase 2 aims to strengthen protective factors of healthy child development and reduce risk factors of child abuse and neglect among disadvantaged families by providing…
- Trial name
- NCT07397637
- Testing
- The Strength-based parenting program
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Central Vein Catheter, Ultrasound
Ultrasound Guidance vs Landmark Technique for Internal Jugular Vein Catheterization
Central venous catheterization (CVC) is a fundamental procedure in anesthesiology and reanimation practice for critical clinical processes such as hemodynamic monitoring, vasoactive drug infusion, and fluid resuscitation.
- Trial name
- NCT07701746
- Testing
- Ultrasound Guidance, Landmark Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Gut Microbiome, Liver Diseases
Assessment of Microorganisms and Host Response In Liver Diseases
The normal human gut is home to millions of microbes including bacteria, fungi, and viruses, collectively forming the gut microbiota, which exists in harmony within us.
- Trial name
- MILD (NCT06291571)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Catheter Malposition, Central Venous Catheterization
Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization
Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration.
- Trial name
- NCT07701720
- Testing
- Ultrasound-Guided Technique, Landmark Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Pseudohypoparathyroidism, Pseudohypoparathyroidism Type 1a
Theophylline for Treatment of Pseudohypoparathyroidism
Pseudohypoparathyroidism is a genetic disorder with limited treatment options, characterized by early-onset obesity, short stature, hormone resistance and cognitive impairment.
- Conditions
- Pseudohypoparathyroidism, Pseudohypoparathyroidism Type 1a, Albright Hereditary Osteodystrophy
- Trial name
- NCT04240821
- Testing
- Theophylline ER
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jaclyn Tamaroff
Firearm Injury
Rise up! A Youth-Informed Video Program For Young Children To Stay Safe From Community Violence
Gun violence is the number one reason children die in the U.S. In big cities, most of these cases come from shootings related to assaults and homicides.
- Trial name
- NCT07548437
- Testing
- Rise Up! video-based program
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
HypnoBreastfeeding, Breastfeeding Education
Evaluation of the Effectiveness of a Hypnobreastfeeding Education Program Based on the ınformation-Motivation-Behavioral Skills Model in Primiparous Women
This randomized controlled trial aimed to evaluate the effectiveness of an education program based on the Information-Motivation-Behavioral Skills (IMB) Model and grounded in the philosophy of hypnobreastfeeding provided to…
- Conditions
- HypnoBreastfeeding, Breastfeeding Education, Pregnancy, Healthy
- Trial name
- (ımb) (NCT07461428)
- Testing
- breastfeeding education program based on hypnobreastfeeding philosophy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Device Convenience, Device Performance
Use of Apple Vision Pro as Virtual Monitor for Diagnostic and Therapeutic Procedures
This study evaluates whether the Apple Vision Pro (AVP), a head-mounted display device, can be used as a virtual monitor for performing diagnostic and therapeutic procedures.
- Conditions
- Device Convenience, Device Performance, Surgeons' Rating, Ergonomics
- Trial name
- NCT07797556
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Osteoarthritis (OA)
Research on the Pathogenesis and Therapeutic Targets of Articular Cartilage Degeneration in Osteoarthritis
Before you are included in this study, you will undergo the following examinations to determine if you are eligible to participate: Before you are included in this study, your doctor will ask and record your medical history…
- Trial name
- NCT07796607
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yunnan University of Chinese Medicine
Sedentary Behavior
The Effect of Aerobic and Resistance Training on the Immune System
Six-week exercise interventions in sedentary young women demonstrated that aerobic exercise and resistance exercise differentially optimize inflammatory and immune responses through their effects on osteocalcin and IgM, and IgA…
- Trial name
- NCT07632911
- Testing
- Aerobic and resistance exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Inonu University
Sleep Apnea, Sleep-Disordered Breathing
The Meaning of Dopaminergic Pathway in Sleep Breathing Disorders.
The participants in the study will be adult patients with suspected sleep-disordered breathing. A one-night polysomnography will be performed using the NOXA1 device (NOX Medical, Reykjavík, Iceland).
- Trial name
- NCT05890911
- Testing
- Polysomnography, Blood dopamine level measurement, Genetical test
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Behavior
Neural Mechanisms for Reducing Interference During Episodic Memory Formation
Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory.
- Trial name
- NCT05092100
- Testing
- Visual stimulus similarity, fMRI, Eye tracking
- Where
- United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Canser, Fear Cancer
Mandala Coloring and Music for Cancer Fear and Screening Anxiety
Cancer screening is important for detecting cancer at an early stage. However, women attending cancer screening may experience fear of cancer and anxiety related to the screening process.
- Conditions
- Canser, Fear Cancer, Anxiety
- Trial name
- NCT07789236
- Testing
- mandala, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
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