Clinical trials: sponsored by NYU Langone Health
Multiple Myeloma, Disease of the Marrow
Evaluation of PET/MR and PET/CT Imaging for Bone Marrow Lesions
Developing an MRI protocol at 1.5 T allowing quantification of the hematopoietic, fatty and trabecular moieties of marrow. An ideal protocol would differentiate red marrow from neoplastic cellular infiltration, and detect loss of…
- Conditions
- Multiple Myeloma, Disease of the Marrow, Osteoporosis
- Trial name
- NCT01880762
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Surgery
Trial of Educational Outcomes of WISE-MD
The purpose of this study is to compare the educational efficacy of instructional design enhancements in on-line learning modules in the context of clinical medical education.
- Trial name
- WISE (NCT01322230)
- Testing
- Control, WISEMD Original, Social Networking
- Where
- 7 sites in United States
- Volunteers
- 1,363 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Childhood Obesity
Healthy Families: Transforming Care for Obese Children at NYU Lutheran Family Health Centers
Childhood obesity is a contributing factor to health complications such as diabetes, heart disease, high blood pressure, cancer and asthma.
- Trial name
- NCT02817009
- Testing
- Social Support, Nutrition Session, Physical Activity Session
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Anorexia Nervosa
Kappa Opioid Receptor Imaging in Anorexia
The purpose of this study is to use positron emission tomography (PET) imaging and magnetic resonance imaging (MRI) to understand the brain function of individuals with anorexia nervosa and healthy controls.
- Trial name
- NCT02240797
- Testing
- Positron emission tomography (PET) imaging
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post-traumatic Stress Disorder (PTSD)
CB1 Receptor PET Imaging Reveals Gender Differences in PTSD
The objective of the proposed translational study is to test a model, based upon basic science studies, exploring multisystem impairments in PTSD including endocannabinoid (eCB) and glucocorticoids in the modulation of fear…
- Trial name
- NCT02237677
- Testing
- Positron emission tomography (PET) imaging
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Major Depressive Disorder, Anhedonia
Kappa Opioid Receptor Imaging in Depression (KOR Depression)
The purpose of this study is to use positron emission tomography (PET) imaging to measure the activity of the kappa opioid receptor (KOR) in the brains of depressed and non-depressed individuals.
- Trial name
- NCT02236702
- Testing
- Positron Emission Tomography (PET) imaging
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Scarring
Medipore Tape Study
This is a prospective, single-blinded, two-arm, randomized, parallel, pragmatic, effectiveness trial that will enroll patients undergoing arthroscopic anterior cruciate ligament reconstruction in order to evaluate the efficacy of…
- Trial name
- NCT02676115
- Testing
- Standard Post Operative Skin Care, Medipore Tape
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sleep Apnea, Obstructive
Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing, or experiences shallow breathing for short periods of time during sleep.
- Trial name
- NCT00393913
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Secondary Traumatic Stress
The Resilience Alliance
The Resilience Alliance is a skill-based staff development intervention for child protective staff that focuses on improving job satisfaction, resilience, optimism and social support, while decreasing attrition, stress reactivity…
- Trial name
- NCT02521571
- Testing
- Resiliance Alliance, Secondary traumatic stress training
- Where
- 4 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy Volunteers
Evaluation of Salt Sensitivity in Young Adults
The current prospective cross-sectional pilot study is proposed to determine a set of characteristic factors associated with salt sensitivity in young adults by measuring blood pressure, serum aldosterone levels, urine analysis…
- Trial name
- NCT02588352
- Testing
- Salt tablet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Atherosclerosis
Serial Phlebotomy in Voluntary Blood Donors
Blood donation has been proposed to be associated with reduced risk of cardiovascular disease, but the effects of phlebotomy on vascular function in human subjects have not been well characterized.
- Trial name
- NCT02762422
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
No Specific Condition
Feasibility of Telephone Follow-up Visits in Primary Care
Doctors frequently speak with their patients over the telephone. Having a visit with a doctor over the telephone rather than face-to-face can be convenient for patients and allow them to save time and money on transportation and…
- Trial name
- NCT02393534
- Testing
- Telephone Visit
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Kidney, Polycystic, Autosomal Dominant
High Water Intake to Slow Progression of Polycystic Kidney Disease
Polycystic kidney disease (PKD) is a genetic disease that occurs in 1 in 500 individuals and leads to kidney failure in half of all affected. Currently, no treatments exist for PKD.
- Trial name
- NCT00784030
- Testing
- Water
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pulmonary TB
Evaluation of the Practice of Three Morning Sputa on Separate Days for Diagnosis of Mtb
Obtain sputum smears within one day to rule out TB
- Trial name
- NCT00212550
- Testing
- Obtain standard three daily sputum samples vs. three samples on the first day for the diagnosis of pulmonary TB.
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Neurofibromatosis 2, Vestibular Schwannoma
Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
The purpose of this study is to determine if Lapatinib has any effect on tumors found in patients with Neurofibromatosis Type 2 (NF2). NF2 is a condition that mainly affects the skin and nervous system.
- Trial name
- NCT00973739
- Testing
- Lapatinib
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
Postoperative Cognitive Decline, Inflammation, and Plasma Levels of Beta-amyloids
Postoperative cognitive dysfunction (POCD) can be a serious complication. The development of therapeutic strategies for the prevention and treatment of this condition requires the identification of subgroup of patients with the…
- Trial name
- NCT00850928
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Congenital Heart Block, Neonatal Lupus
Dexamethasone Treatment for Congenital Heart Block (CHB) in Newborns With Lupus
Some newborns are born with congenital heart block (CHB), a condition occurring in babies with neonatal lupus. The first part of the study will test the effectiveness of fluorinated steroids, including dexamethasone, in improving…
- Conditions
- Congenital Heart Block, Neonatal Lupus, Atrioventricular Nodal Dysfunction, Myocardial Injury
- Trial name
- NCT00007358
- Testing
- Dexamethasone or other corticosteroid
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Epilepsy
Women With Epilepsy: Pregnancy Outcomes and Deliveries
This is a three-center prospective case-control study to examine the patterns of fertility among women with epilepsy (WWE) compared to an age-matched group of women without epilepsy (WWoE).
- Trial name
- WEPOD (NCT01259310)
- Where
- 3 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post-traumatic Stress Disorder (PTSD), Trauma
Functional Brain Imaging in PTSD
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume.
- Trial name
- NCT02053532
- Testing
- Positron emission tomography/magnetic resonance imaging
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Spasmodic Dysphonia, Dystonia
Effect of Vocal Exercise After Botulinum Toxin Injection for Spasmodic Dysphonia
Studies have suggested that voluntary muscle exercise in the hand and face after botulinum toxin injection may enhance the clinical effects of the toxin.
- Trial name
- NCT00895063
- Testing
- Vocal Exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health