Clinical trials: sponsored by NYU Langone Health
Healthy
Anti-platelet Effects of Colchicine in Healthy Volunteers
This is a pilot study. Volunteers will be given 1.8 mg (1.2 mg followed by 0.6 mg one hour later), 1.2 mg, or 0.6 mg of colchicine.
- Trial name
- NCT02140372
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pemphigus Vulgaris
Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus
The purpose of this study is to compare two standard treatments for pemphigus to determine which more effectively improves the clinical manifestations of the disease and decreases serum level of the autoantibodies which cause the…
- Trial name
- NCT00483119
- Testing
- intravenous immunoglobulin, cyclophosphamide
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
COPD
Adverse Health Effects of Mainstream and Secondhand Hookah Smoke in NYC Hookah Bars
The primary purpose of this study is to examine the health effects of mainstream and secondhand hookah (i.e. water pipe) smoke on pulmonary and cardiovascular functions as well as serum levels of inflammatory biomarkers.
- Trial name
- NCT02638194
- Testing
- Active smoking of Tobacco Hookah for 2 hours, Exposure to tobacco hookah second hand smoke, Visit a win bar
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Medical Knowledge, Clinical Performance
Utility of High-Fidelity Simulation In the Education and Assessment of Residents in the Recognition and Management of the Sepsis Syndrome
The primary objective of the proposed study will be to determine if a multi-modality teaching curriculum utilizing high-fidelity simulation and didactic lecture will result in sustained improvement by internal medicine residents…
- Trial name
- NCT01992120
- Testing
- Debriefing of high-fidelity sepsis simulation scenarios
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Overactive Bladder
Feasibility of "At-home" Titration of Solifenacin
This is an open-label single center trial to study improvements in symptom bother and quality of life in overactive bladder patients self titrating solifenacin 5mg and 10 mg.
- Trial name
- NCT00759577
- Testing
- Solifenacin
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Fibromyalgia
Brain Rhythms in Fibromyalgia: A Magnetoencephalography (MEG) Study
The long-term purpose of the investigator's research is to understand the pathophysiological basis of chronic pain. This will help provide a framework for the development of effective treatments.
- Trial name
- FMP (NCT02159300)
- Testing
- experience brain activity recording
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
DIabetes
Remote Simultaneous Medical Interpreting and Medical Outcomes
All new patients to the general medicine clinic who were not primarily English speaking were randomized, after consenting, to receieve either remote simultaneous medical interpreting or usual and customary interpreting services.
- Trial name
- RSMI (NCT00522327)
- Testing
- remote simultaneous medical interpreting, usual and customary, ENglish speaking
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Contraception Behavior
Immediate vs. Delayed Insertion of Copper T 380A IUD After Termination of Pregnancy Over 12-weeks Gestation
The purpose of this study is to compare delayed vs. immediate insertion of the Copper T 380 IUD after termination of pregnancy after 12 weeks.
- Trial name
- NCT00540046
- Testing
- Copper T 380A IUD
- Where
- 2 sites in United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Delirium, Postoperative Cognitive Dysfunction
Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
The purpose of this study is to determine whether preoperative administration of Rivastigmine prevents the incidence of postoperative delirium in patients undergoing major surgery as well as postoperative cognitive dysfunction.
- Trial name
- NCT00835159
- Testing
- Rivastigmine Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hypertension, Brain Tumor
A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients
This protocol describes a study to gain experience in the use of Clevidipine for perioperative blood pressure control in patients undergoing craniotomy for brain tumor or epilepsy focus resection.
- Conditions
- Hypertension, Brain Tumor, Epilepsy
- Trial name
- NCT00952081
- Testing
- Clevidipine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis, Psoriatic Arthritis
Role of Oral and Intestinal Microbiota in Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is an inflammatory form of arthritis that causes joint pain and damage. RA attacks the lining of the joints (synovium), causing swelling that can result in aching and throbbing, and eventually deformity.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Periodontal Disease
- Trial name
- NCT01198509
- Testing
- doxycycline, vancomycin
- Where
- 2 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alzheimer's Disease
Effects of Memantine on Magnetic Resonance (MR) Spectroscopy in Subjects at Risk for Alzheimer's Disease
Recent data show that marked cell damage precedes the clinical manifestation of Alzheimer's disease (AD). Hence, targeting populations at risk with pharmacological interventions is a possible strategy to lessen the burden of the…
- Trial name
- NCT00933608
- Testing
- memantine
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Anxiety Disorders, Separation Anxiety Disorder
A Research Study of How Teens With and Without an Anxiety Disorder Make Decisions
The purpose of this trial is to study how teens with and without an anxiety disorder make decisions. This is a brain imaging study using functional magnetic resonance imaging (fMRI) in adolescents between the ages of 13 and 17.
- Conditions
- Anxiety Disorders, Separation Anxiety Disorder, Phobic Disorders
- Trial name
- NCT00104195
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Herpes Zoster
Increasing Use of the Vaccine Against Herpes Zoster/Shingles at NYULMC and Bellevue Hospital
The purpose of this study is to determine if vaccination rate of eligible patients at a major urban public hospital will increase by having ophthalmologists screen patients for eligibility and a nurse administer the vaccine in…
- Trial name
- NCT01483378
- Testing
- Choosing to receive the vaccine
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Conduct Disorder
Early Prevention of Conduct Problems
The purpose of this study is to examine the immediate and long-term effects of a prevention program in children at risk for developing conduct problems and antisocial behavior.
- Trial name
- NCT00051714
- Testing
- Family-Based Preventive Intervention
- Where
- United States
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Asthma
MethaCholine Bronchoprovocation Study (MeCIS)
The purpose of this research is to evaluate the methacholine challenge test as an accurate indicator of asthma in patients receiving treatment for asthma.
- Trial name
- MeCIS (NCT00705341)
- Testing
- fluticasone
- Where
- 13 sites in United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Stroke With Hemiparesis
Transfer of Grasp Control Across Hands After Stroke
The purpose of this study is to examine if the strong hand can assist in the recovery of muscle function in the weak hand after a stroke.
- Trial name
- NCT00589368
- Testing
- Transfer of grasp control across hands
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Genital Herpes
Serologic Assays for the Diagnosis of Herpes Simplex Virus Type 2
The purposes of this study are: To determine the accuracy of commercially available serologic assays in diagnosing patients with herpes simplex virus type 2 (HSV-2); To assess the sensitivity and specificity of the commerical…
- Trial name
- NCT01112956
- Where
- 3 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Pain
Jet Lidocaine for Pain Relief During Needle Insertion in a Pediatric Emergency Department
The purpose of this study is to explore to what degree, if any, Jet lidocaine will reduce or alleviate pain, as compared to Jet normal saline, in children undergoing needle insertion in the Pediatric Emergency Department (PED).
- Trial name
- NCT00681902
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colorectal Cancer
Trial of a Multilevel Intervention to Increase Colorectal Cancer Screening
This study will assess the effectiveness of a culturally-responsive intervention to increase colorectal cancer (CRC) screening among Latino immigrants in a primary care clinic setting of a large municipal Hospital in New York…
- Trial name
- NCT00836303
- Testing
- Colorecatal Cancer Screening Activation
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health