Clinical trials: enrolling by invitation
Systemic Lupus Erythematosus (SLE), Visual Function
Study on Early Visual Dysfunction in Patients With Systemic Lupus Erythematosus
OCT, OCTA, fundus photography, and fundus autofluorescence ( FAF ) were used to observe the fundus physiological indexes of normal subjects and SLE patients, to explore the differences of subclinical retinal damage in SLE…
- Trial name
- NCT07679776
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
ACL Injuries
Menstrual Cycle-Synced Neuromuscular Training
This is a research study of female athletes participating in at least one running/cutting sport, who have no current conditions that would limit ability to perform sport-like movement tasks (such as running or jumping), and have…
- Trial name
- NCT06983184
- Testing
- MC-synced NTP, Blinded NTP
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Sophia Ulman
Cardiovascular Diseases
Continuation of the nuMoM2b Heart Health Study
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women.
- Trial name
- nuMoM2b-HHS2 (NCT05472597)
- Where
- 14 sites in United States
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- RTI International
Closed Sinus Lift, Apigenin Loaded Scaffold
Closed Sinus Lifting Using Xenograft With or Without Liposomal Apigenin-Loaded Scaffold
aims to evaluate the effectiveness of closed sinus lifting using xenograft with or without a liposomal Apigenin-loaded scaffold in the posterior maxilla.
- Trial name
- NCT07678749
- Testing
- sinus lifting
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Extraterrestrial Habitation Systems, Lunar Surface Habitation
A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface
This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the…
- Conditions
- Extraterrestrial Habitation Systems, Lunar Surface Habitation, Lunar Water-Ice Resource Assessment, In-Situ Resource Utilization (ISRU)
- Trial name
- LUMEN-HAB (NCT07546461)
- Testing
- Habitat Systems Evaluation, Water-Ice Resource Utilization Assessment, EVA and Mobility Operations
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Tobacco Cessation
Tobacco Cessation Texting Intervention for People Living With HIV Who Smoke in Vietnam
The intersection of smoking and HIV/AIDS poses a serious public health threat in Vietnam. Vietnam is dealing with these two challenges with parallel rather than integrated plans.
- Trial name
- M2Q2-HIV (NCT05863923)
- Testing
- mHealth Messaging to Motivate Quitline use and Quitting among Persons Living With HIV (PLWH) in Vietnam (M2Q2-HIV), M2Q2-HIV Comparison
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Coarctation of the Aorta, Aortic Arch Obstruction
The Arch Watch Study: An Integrated Evaluation of Hemodynamics in Infants With Suspected Coarctation of the Aorta
Unrecognized coarctation of the aorta (CoA) is a life-threatening component of congenital heart disease (CHD) in which narrowing of the aorta causes obstructed blood flow to the lower half of the body; it can occur in isolation…
- Trial name
- NCT05880576
- Testing
- Monitoring using resonance Raman spectroscopy, pulse oximetry, blood pressure, and near-infrared spectroscopy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Bleaching; Satisfactory, Bleaching Sensitivity
Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction
The purpose of this study was to conduct a randomized double-blind clinical trial to examine the efficacy of an in-office bleaching regimen with varied activation modes on color stability, surface roughness, tooth sensitivity…
- Conditions
- Bleaching; Satisfactory, Bleaching Sensitivity, Bleaching Efficacy
- Trial name
- NCT07493941
- Testing
- 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation, 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Orthognathic Surgical Procedures, Patient Specific Implant
Maxillary Positioning in Orthognathic Surgery
Patient that need corrective Jaw Surgery went into Maxillary Positioning in one of two groups either Maxilla Fixed using occlusal waver or PSI
- Trial name
- NCT07671794
- Testing
- Maxillary Orthognathic Surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Colorectal Cancer Screening
Large-Scale Implementation of a Decision Aid About Colorectal Cancer Screening
The goal of the project is to improve shared decision making and increase uptake of colorectal cancer (CRC) screening by facilitating the implementation of a decision aid about CRC and screening options in two healthcare systems…
- Trial name
- IDecide (NCT06597955)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Indiana University
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Breast - Female
Feasibility of Comparing Microwave Images to Clinical Information in Patients Recalled for Follow-up Breast Imaging
The goal of this clinical trial is to measure the electrical properties of breast tissues using microwave technology and to compare these collected measurements to clinical information in mammograms and/or breast ultrasound for…
- Trial name
- NCT07273565
- Testing
- WVI-MIS-02-2025
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sleep
The Efficacy of ICU Diary on Sleep, Fatigue and Stress
To create a constructive ICU diary and to comprehend the effect of Constructive ICU Diary on Stress, Sleep Disturbances and Fatigue of Primary Family Caregiver in ICUs.
- Trial name
- NCT07631260
- Testing
- ICU diary
- Where
- Taiwan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Taichung Tzu Chi Hospital
Alzheimer Disease
Learning Amyloid and Tau Results
This is a prospective, single-cohort, single-center, observational study to assess if learning one's Alzheimer's disease biomarker test result impacts longitudinal psychosocial, behavioral, and neuropsychological outcomes, and to…
- Trial name
- NCT07222930
- Testing
- Disclose amyloid, tau results, Follow-up Assessments
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Iron Deficiency Anemia in Preterm Neaonates
Liposomal Iron Versus Ferrous Iron Supplementation for Early Prophylaxis of Iron Deficiency Anemia in Preterm Neonates
Iron prophylaxis will be initiated at age of 2-3 weeks at a dose of 3mg/kg/day. Standard care group: will receive ferrous iron (Enrich oral drops(50mg/ml), one drop per kilogram of body weight daily.
- Trial name
- NCT07667205
- Testing
- Daily oral ferrous ion, Daily oral liposomal iron, Oral liposomal iron every other day
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Knee Arthritis Osteoarthritis
Comparison Between Velys J&J Robotic-assisted and Cori S&N Robotic-assisted Total Knee Arthroplasty
This randomised controlled trial will include patients with end-stage osteoarthritis of the knee undergoing primary TKR. Patients meeting the criteria that consent to be in the study will be randomised at a ratio of 1:1 to either…
- Trial name
- TKA (NCT07555067)
- Testing
- preoperative HKA, preoperative CPAK, preoperative Oxford Knee Score
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jan Biziel University Hospital No 2 in Bydgoszcz
Neurodevelopmental Disorder (Diagnosis)
Virtual Reality Headset as an Alternative Tool for Reducing Dental Anxiety
The aim of this study is to investigate whether the use of virtual reality (VR) headsets can have a positive effect on dental fear during dental procedures and stress induced by the dental environment.
- Trial name
- NCT07667023
- Testing
- Virtual reality headset, standard dental care
- Where
- Hungary
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Oxidative Stress, Inflammation
Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes
Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with…
- Conditions
- Oxidative Stress, Inflammation, Physical Fitness, Echocardiography
- Trial name
- NCT07662954
- Testing
- Spinning Training, Magnesium Supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles.
- Conditions
- Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
- Trial name
- NCT07349966
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Myopia, Progressive
Management of Myopia in University Students Using Dual Focus Soft Contact Lenses
The purpose of the study is to quantify the effectiveness of Coopervision MiSight contact lenses in slowing the rate of myopia progression in university students.
- Trial name
- MoMUS (NCT05955638)
- Testing
- MiSight contact lenses, Proclear contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bradford
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