Clinical trials: enrolling by invitation
Evaluate Effect of Nebulized Dexmedetomedine Upon Blunting Autonomic Response of Laryngoscopy and Intubation in Patients Undergoing Elective Intubation
To Evaluate Effect of Nebulized Dexmedetomedine Upon Blunting Autonomic Response of Laeyngoscopy and Intubation in Patients Undergoing Elective Intubation
Laryngoscopy and intubation are painful stimuli ,that results in adverse physiological outcomes,like tachycrdia ,hypertension,arrythmiaa,pulmonary edema.
- Trial name
- NCT07480304
- Testing
- Nebulization of dexmedetomedine in group D, Nebulizition with normal saline in group C,after taking informed consent patients in group cwill be nebulized with 5 ml of normal saline 30 min prior to elective intubation ,HR,SBP,DBP,MAP monitored.
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Insomnia
Smart Devices-based Longitudinal Assessment of Patterns of Insomnia
The objective of the study is to develop an algorithm to detect insomnia and classify its severity, based on data collected during the use of Withings products and from questionnaires sent to users
- Trial name
- SLEEPI (NCT07430878)
- Testing
- Use of the Withings sleep-related devices, Questionnaires
- Where
- France
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Withings
Diabetic Foot Ulcer, Wound Healing
Tele-Exercise Platform for Plantar Wound Healing
The purpose of the study is design and use a telemedicine platform which integrates video-chat, pre-programmed interactive game-based foot, and ankle exercise modules, and real-time quantitative performance metrics displayed to…
- Conditions
- Diabetic Foot Ulcer, Wound Healing, Wound Care
- Trial name
- Tele-FootX (NCT06439667)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Vascular Stiffness
NRM on Vascular Perfusion in Healthy Adults
The purpose of this study is to better understand the effects of nicotinamide riboside supplement in overall cardiovascular health in healthy adults.
- Trial name
- NRM (NCT06345443)
- Testing
- Nicotinamide Riboside Malate
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Food Insecurity, Health Behavior
Food Access, Value, and Optimization of Resources
The main goal of the study is to examine the potential benefits of an educational workshop designed to help and support caregivers of children in families that struggle to get enough healthy food.
- Conditions
- Food Insecurity, Health Behavior, Nutrition, Social Determinants of Health
- Trial name
- FAVORes (NCT07149350)
- Testing
- FAVORes Workshop
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Tobacco Dependence, COPD Asthma
Cytisine vs Nicotine Replacement Therapy
Tobacco is the most preventable cause of disease and death in Canada. Although the tobacco use rate has substantially gone down in the general population, significant differences exist between sub-populations in Canada, for…
- Conditions
- Tobacco Dependence, COPD Asthma, Mental Illness, Substance Use
- Trial name
- NCT03249428
- Testing
- Cytisine, Nicotine replacement therapy (NRT)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Posture
The Effects of a Customized Exercise Program on Pain, Kyphosis Angle, and Quality of Life
The aim of this study is to evaluate the effect of a customized corrective exercise program on back pain, kyphosis degree, and quality of life in healthy adults.
- Trial name
- Exercise (NCT07477847)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Rumeli University
Acute Pain, Experimental Pain in Healthy Human Participants
Healthy Children and Virtual Reality Mediation of Simulated Pain
The objective of this study is to develop central nervous system (CNS) biomarkers of pain experienced during medical procedures and pain relief induced by Virtual Reality Pain Alleviation Therapy (VR-PAT).
- Conditions
- Acute Pain, Experimental Pain in Healthy Human Participants, Children, Adolescents
- Trial name
- NCT06854991
- Testing
- Active VR-PAT, Passive VR-PAT, iPad
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Obstructive Sleep Apnea
Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to Severe Obstructive Sleep Apnea.
The goal of this observational study is to characterize the performance of the SleepView+ home sleep test system for the evaluation of moderate to severe obstructuve sleep apnea (OSA) in adult and pediatric patients (ages 12 and…
- Trial name
- NCT07476313
- Testing
- SleepView+
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beacon Biosignals
Joint Hypermobility
Characteristics of the Functional State of the Musculoskeletal System, Body Awareness, and Quality of Life in Individuals With Joint Hypermobility, Their Associations, and Guidelines for Intervention.
The goal of this observational study is to learn about the characteristics of the functional state of the musculoskeletal system, body awareness, and quality of life in individuals with joint hypermobility, their associations…
- Trial name
- NCT07476976
- Testing
- No intervention
- Where
- Lithuania
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Facial Skin Laxity
Study on the Efficacy and Safety of PLLA Injections for Improving Facial Laxity Following GLP-1 Analog Therapy
Following weight loss with GLP-1 receptor agonists, facial skin laxity and sagging have become another concern for some patients.
- Trial name
- PLLA-GLP-1 (NCT07478198)
- Testing
- PLLA injection
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shanghai Punan Hospital of Pudong New District
Pressure Injury, Pressure Injury Prevention
The Effect of a Color-Coded System on Pressure Injury Prevention in the Intensive Care Unit
This study is designed as a randomized controlled trial to examine the effect of using a color-coded classification system that identifies the risks of pressure injuries in the intensive care unit on the development of pressure…
- Conditions
- Pressure Injury, Pressure Injury Prevention, Risk Assessment, Nursing Care
- Trial name
- ICU PI Colors (NCT07470918)
- Testing
- Color-Coded Pressure Injury Risk Assessment Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Questionnaires, Validation
Adaptation and Validity of the Lithuanian Version of the Baecke Physical Activity Questionnaire
The aim of this study is to adapt the Baecke Questionnaire of Habitual Physical Activity for use in Lithuania. Individuals who meet the following criteria may participate in this study: Adults aged 18 years or older.
- Trial name
- NCT07402889
- Testing
- No Interventions
- Where
- Lithuania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ernesta Aukštuolytė
Genetic Predisposition, Exposure, Environmental
Mayo Clinic Precure - Prospective Study
The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease…
- Trial name
- NCT07332598
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Best Practices, Ellacor
Safety and Efficacy of Ellacor® Micro-coring® Following Best Practices on Technique and Post-Procedural Care
Since its inception of being marketed in the United States in 2021, physicians have used various post procedure skin care regimen to facilitate recovery.
- Conditions
- Best Practices, Ellacor, Micro-coring Post Care, Ellacor Post Care
- Trial name
- NCT07260578
- Testing
- ellacor Micro-Coring Technology
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
HIV Infections
Getting to Zero Among HHI MSM in the American South
This study will evaluate a status-neutral integrated strategy to improve access to and uptake of HIV prevention and treatment services for the highest HIV incidence (HHI) men who have sex with men (MSM) in participating…
- Trial name
- NCT05075967
- Testing
- Health Access Coalitions, Social Media, Peer Support
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Caffeine, Placebo - Control
Effects of Caffeine Ingestion on Morning Cognitive and Muscle Repeated Sprint Performance in Males
Athletes often compete in the morning when they are biologically weaker; normally in competition heats or quarterfinals to qualify for the finals scheduled in the evening.
- Conditions
- Caffeine, Placebo - Control, No Pill
- Trial name
- NCT07466732
- Testing
- Caffeine, Placabo, No Pill
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome)
Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.
This study will evaluate how well the a new stool test can distinguish inflammatory bowel disease (IBD) from non-IBD conditions compared with standard calprotectin testing and colonoscopy findings.
- Conditions
- IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome), Gastrointestinal Symptoms
- Trial name
- COMBI (NCT07471490)
- Where
- 2 sites in United States, Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DiaSorin Inc.
Central Nervous System Disease, MRI
Validation on Clinical Adaptability of the Foundation Model Specific to Neuroimaging Diagnosis
This clinic trial aims to investigate whether artificial intelligence (AI) diagnostic tools at neurological diseases diagnosis on brain CT/MRI can improve the work efficiency of specialized neuroimaging physicians, with a…
- Conditions
- Central Nervous System Disease, MRI, CT, AI (Artificial Intelligence)
- Trial name
- NCT07471984
- Testing
- Foundation Model Specific to Neurological Diagnosis
- Where
- China
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Yaou Liu
Urinary Incontinence
Outcomes of Urinary Incontinence Treatment in Primary Care: APP Co-Management and Electronic Consult
The burden of urinary incontinence (UI) on American women is immense in both human and financial terms, and continues to rise with the aging US population.
- Trial name
- OUTPACE (NCT06040645)
- Testing
- APP Co-management, E-consult
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
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