Clinical trials: enrolling by invitation
Healthy Subjects
Clinical Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of HSK31858 in Healthy Subjects
This is a single-center, open-label, two-period, fixed-sequence clinical study to evaluate the effect of Itraconazole on the pharmacokinetics of HSK31858 in healthy subjects
- Trial name
- NCT07134465
- Testing
- HSK31858 Tablets and Itraconazole Capsules
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy, Multiple Sclerosis
Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)
Major brain diseases (including neuroimmune diseases, neurodegenerative diseases, and cerebrovascular diseases) are leading causes of death and disability in humans.
- Conditions
- Healthy, Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Neurodegenerative Diseases
- Trial name
- NCT06643858
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Neuromuscular Disease
B3 for NMD: Bench to Bedside and Back
Background: Neuromuscular diseases (NMD) represent a broad group of rare genetic and acquired disorders, affecting over 300,000 people in Canada.
- Trial name
- NCT04417023
- Testing
- B3 for NMD: Bench to Bedside and Back
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Chiari Malformations
Dynamic MRI and Quantitative MR CSF Flow Studies in Craniovertebral Junction Anomalies
The purpose of this study is to decide which position of the neck affects cerebral spinal fluid (CSF) flow between the spinal cord and the brain.
- Trial name
- NCT00795080
- Testing
- Dynamic cervical MRI scans
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women
Trial to Evaluate the Impact of Various Behavioural Interventions to Increase Mammography Uptake Among Singaporean Women
Breast cancer is the leading cancer among women in Singapore, yet mammography screening rates remain critically low at 34.7%, despite the availability of a national program since 2002.
- Trial name
- PROMPT (NCT07283107)
- Testing
- Arm 2: One mailed reminder, Arm 3: Two mailed reminders, Arm 4: Mailed reminder with prescheduled appointment
- Where
- Singapore
- Volunteers
- 8,910 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Intraocular Pressure
External Influences Upon Ocular Homeostasis
Our experiments are designed to test the overall hypothesis that position-dependent or water-dependent intra-ocular pressure (IOP) spikes occur in humans, and that these challenge ocular homeostasis.
- Trial name
- NCT00338065
- Testing
- Postural change, Water drinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Rejuvenation, Skin Care Dermocosmetics
Consensus on Skin Care in Breast Cancer Patients
Skin toxicity is one of the most common and impactful adverse effects of breast cancer treatment, affecting patients undergoing chemotherapy, targeted therapies, endocrine therapy, and radiotherapy.
- Conditions
- Rejuvenation, Skin Care Dermocosmetics, Breast Cancer
- Trial name
- NCT07306130
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Research Center
Nursing Students, Intimate Partner Violence (IPV)
The Effect of Simulation Training on Nursing Students' Perception, Myths and Attitudes of Dating Violence
Violence is a major global public health problem, causing approximately 1.5 million deaths each year. Dating violence, a common form of violence among young people, has serious consequences for women's and youths' physical and…
- Trial name
- NCT07297992
- Testing
- High-Fidelity Simulation-Based Education, Flipped Classroom-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Hypotension During Surgery
The Noninvasive Blood Pressure Measurement Effect on the Hypotension
Around 300 million surgical operations are performed globally, and of these, 40 to 50 million are performed in the USA. The perioperative period is characterized by hemodynamic instability and, most importantly, hypotension.
- Trial name
- NCT05993481
- Testing
- Blood Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Pain, Back
Tune Up Your Back: Soundwave Wellness Study
Looking to support your back mobility and overall comfort? Join our study exploring WAVwatch 2.0, an innovative soundwave therapy device.
- Trial name
- NCT07256626
- Testing
- WAVWatch 2.0
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Mental Status Change
Sun-Kissed Serenity: Morning Rays for a Brighter Mind
Sun-Kissed Serenity: Morning Rays for a Brighter Mind is a 30-day dawn rendezvous with nature. Participants are asked to stand outside for 15 minutes each morning, track progress with surveys, and support mental health with…
- Trial name
- NCT07256574
- Testing
- Morning sunlight
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Maternal Vital Signs, Skin-to-skin Contact
The Effect of Skin-to-Skin Contact Applied in the Early Postpartum Period on Maternal Pain, Birth Satisfaction, and Maternal Vital Signs Dynamics
Skin-to-skin contact (STSC) initiated within the first hour after birth is a fundamental practice that supports both the mother's and the newborn's physiological and psychological adaptation (Çelik \& Kök, 2022).
- Conditions
- Maternal Vital Signs, Skin-to-skin Contact, Birth Satisfaction
- Trial name
- NCT07304037
- Testing
- A solid hour of skin-to-skin contact
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Post-partum Depression
PreParent: Internet-based Digital Tools to Screen for and Prevent Postpartum Depression in Parents-to-be
The goal of this randomized controlled study is to evaluate whether an online intervention that combines psychoeducation and affective cognitive training can help prevent postpartum depression in pregnant women and co-parents who…
- Trial name
- NCT07302165
- Testing
- Online prenatal affective cognitive training
- Where
- Denmark
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Diabetes Mellitus Type 1, Healthy Ageing
FinnDiane LifeOne Study - Impact of Ageing on People With Type 1 Diabetes
Healthy aging refers to functional ability that enables well-being in older individuals. The focus thus shifts from chronological age to functional capacity and the individual's own experience of well-being.
- Trial name
- LifeOne (NCT07289204)
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Energy
Morning Water Study
This study aims to determine the efficacy of morning water consumption on reducing fatigue and boosting daily productivity. Participants will receive personalized feedback on how their morning hydration influences their energy…
- Trial name
- NCT07256587
- Testing
- Drink 24 ounces of water
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Dental Disease, Behavioral Changes
Personalized Digital Coaching for Oral Hygiene Adherence: Randomized Controlled Trial.
The goal of this clinical trial is to learn if a personalized Digital Oral Health Intervention (DOHI) improves how well adults follow recommended tooth brushing routines.
- Trial name
- NCT07167875
- Testing
- Personalized Digital Oral Health Coaching
- Where
- 2 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dental Caries, Class II Dental Caries
Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite
Introduction: Resin-based composites (RBCs) have become the gold standard in restorative dentistry due to their superior aesthetics, adhesion, and minimally invasive application.
- Trial name
- NCT07262086
- Testing
- Resins, Composite nanohybrid, Resins, Composite bioactive
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Attitude of Health Personnel
Manual Therapy Behavior Scale in Physiotherapists
The aim of this study is to develop a scale to assess the manual therapy application behaviors of physiotherapists in Türkiye, based on the Theory of Planned Behavior (Ajzen, 1991).
- Trial name
- NCT07296380
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Uşak University
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