Clinical trials: enrolling by invitation
Perinatal Depression, Stepped Care
A Randomized Controlled Trial of the "Psychological Training Camp & Obstetrician-Led Psychoprenatal Intervention (PICONI)" Stepwise Intervention Model for Depression and Anxiety During Pregnancy.
In this study, pregnant women were screened and managed for depression and anxiety in three time windows: early pregnancy, mid-pregnancy, and late pregnancy.
- Conditions
- Perinatal Depression, Stepped Care, Perinatal Anxiety
- Trial name
- NCT06383221
- Testing
- "Mental Fitness Boot Camp - Advanced Counseling" Step-by-Step Care
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Undiagnosed Disease, Rare Diseases
Rare and Undiagnosed Disease Research Biorepository
This research study is being done to find markers and identify causes of rare and undiagnosed diseases by analyzing patient's DNA (i.e., genetic material), RNA, plasma, urine, tissues, or other samples that could be informative…
- Trial name
- PRaUD (NCT04703179)
- Testing
- Genetic test evaluation
- Where
- 3 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Athletes
The Role of Luteolin Supplementation in Cellular Metabolism of Myocytes and Fat Cells, Physical Performance, and Body Composition in Athletes.
A clinical trial is to determine whether Luteolin supplementation can enhance cellular metabolism and improve physical performance in apparently healthy Jordanian male athletes aged 18-35 with continuous training experience.
- Trial name
- NCT07280520
- Testing
- luteolin
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Preeclampsia
Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women
Primary outcome 1. to identify biological changes in nulliparous women at high risk for preeclampsia defined by combined screening by Fetal Medicine Foundation (FMF) 2.
- Trial name
- PRERISK (NCT06200571)
- Where
- 2 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Schizophrenia Disorder, Frontotemporal Dementia, Behavioral Variant
Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.
Clinical Study A. Retrospective Neuropathological Study of Synapse dysfunction. This is a cross-sectional study of patients retrospectively collected from existing postmortem collections and from existing collections of…
- Conditions
- Schizophrenia Disorder, Frontotemporal Dementia, Behavioral Variant, Major Depressive Disorder (MDD), Bipolar Disorder (BD)
- Trial name
- NCT07234851
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Healthy Adults
Normative Data for Cardiorespiratory Fitness in Healthy Adults
Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle…
- Trial name
- NDFCFIHAUTQCST (NCT07275619)
- Where
- Pakistan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Adult
Impact of Aerobic Exercise on Pain Modulation in Healthy Adults
Exercise-Induced Hypoalgesia (EIH) refers to reduced pain sensitivity following exercise, particularly in response to noxious stimuli.
- Trial name
- NCT07083219
- Testing
- Aerobic High Intensity Interval Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Alzheimer Disease
GeneMatch: A Program of the Alzheimer's Prevention Registry to Match Individuals to Studies Based on Apolipoprotein E (APOE) Genotype
The purpose of the Alzheimer's Prevention Registry GeneMatch program is to identify a large group of people interested in participating in research studies or clinical trials based in part on their genetic background.
- Trial name
- NCT02564692
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Banner Health
Airway Disease
Determining Airway pH by Compartmental Exhaled Nitric Oxide Levels During Alkaline Buffer Challenge
Airway pH imbalances cause numerous adverse physiological changes within the airways, including hyperreactivity, cough, bronchoconstriction, ciliopathy, decreased response to bronchodilators, bacterial growth…
- Trial name
- NCT04738422
- Testing
- Alkaline glycine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Indiana University
Nurse, Self-Efficacy
Applying the ADDIE Model to Develop a Multimedia Program to Enhance Chemotherapy Knowledge and Self-Efficacy Among Intensive Care Unit Nurses
Research Methods, Procedures, and Participant Requirements: This study will test a multimedia interactive learning system designed to help nurses conveniently learn about chemotherapy drug administration.
- Conditions
- Nurse, Self-Efficacy, eLearning, Chemotherapy
- Trial name
- ADDIE (NCT07269132)
- Testing
- Interactive multimedia education
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Achalasia, Gastric Fistula
Outcome Analysis of POEM and Endoluminal Therapies
Evaluation of current and newly developed endoluminal therapies in the management of Upper and Lower GI conditions.
- Conditions
- Achalasia, Gastric Fistula, Weight Gain After Primary Weight Loss Surgery, Marginal Ulcer
- Trial name
- NCT03123835
- Testing
- Endoscopic Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Autism Spectrum Disorder
Translating Evidence-based Interventions for ASD: Multi-Level Implementation Strategy
The purpose of this study is to test the effectiveness of the "Translating Evidence-based Interventions (EBI) for ASD: Multi-Level Implementation Strategy" (TEAMS) model on provider-level implementation outcomes when used to…
- Trial name
- TEAMS (NCT03380078)
- Testing
- Teams Leadership Institute (TLI), Motivational Enhancement (TIPS for Training), Classroom Pivotal Response Teaching (CPRT)
- Where
- 3 sites in United States
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Alzheimer Disease, Mild Cognitive Impairment
Can (Optical Coherence Tomography) Pictures of the Retina Detect Alzheimer's Disease at Its Earliest Stages?
Years before someone experiences the symptoms of Alzheimer's disease, a compound called amyloid beta (Aβ) builds up in the brain. Excess Aβ - directly or indirectly - causes many of the symptoms of Alzheimer's dementia.
- Trial name
- NCT06023446
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Wellbeing
Testing a Novel Attention Based Training Prevention Strategy for First Responders: FirstFocus a Mobile App
First responders are frequently exposed to high-stress and traumatic events, putting them at increased risk for mental health challenges such as posttraumatic stress disorder, anxiety, and depression.
- Trial name
- NCT07247149
- Testing
- Attention Bias Modification
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Palo Alto University
Dementia
The Effect of a Comprehensive Dementia Education Program on Improving Attitudes Toward People Living With Dementia
This randomized controlled trial focuses on Indonesian nursing students and examines the effectiveness of virtual reality (VR) dementia education programs. The study addresses the following research questions: 1.
- Trial name
- VReducationRCT (NCT07265856)
- Testing
- Comprehensive VR Program, Conventional Lecture Program (Non-VR)
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Gynecological Disorders, Male Infertility
Biobank Aimed to Study Gynecological Pathologies, of Male and Female Infertility and Pregnancy Pathologies
The REPRO-Biobank has been established at San Raffaele Hospital in Milan for the purpose of collecting and preserving human biological samples and associated data.
- Conditions
- Gynecological Disorders, Male Infertility, Female Infertility, Pregnancy
- Trial name
- NCT07265908
- Testing
- Blood sampling
- Where
- Italy
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
School Attendance, School Climate
The University of Oregon ACCESS Project
The goal of this clinical trial is to learn if two behavioral interventions work to reduce office disciplinary referrals, improve attendance, and reduce depression and anxiety in 7th grade students.
- Conditions
- School Attendance, School Climate, School Engagement, School Exclusion
- Trial name
- NCT07264621
- Testing
- Inclusive Skill-building Learning Approach (ISLA), Family Check-Up Online (FCU-O), FCU-Online with telehealth coaching
- Where
- 13 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Dental Anxiety
Musical Intervention for Dental Anxiety
The goal of this clinical trial is to learn if listening to music during dental procedures lowers anxiety in adults. The main questions it aims to answer are: does music during the procedure lower dental anxiety, and does wearing…
- Trial name
- MI-DENT (NCT07240233)
- Testing
- Music via headphones, Headphones without audio
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Kidney Stone, Pain, Postoperative
Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy
The goal of this pilot clinical trial is to learn whether meditation can help improve recovery in children and adults having surgery for kidney stones.
- Conditions
- Kidney Stone, Pain, Postoperative, Anxiety Postoperative
- Trial name
- MEDITATE (NCT06783946)
- Testing
- Meditation
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Pregnancy
Exercise During Pregnancy: Effects on the Maternal-Fetal Unit
Metabolic alterations during pregnancy have been associated with adverse maternal-fetal outcomes, including low birth weight and pregnancy complications.
- Trial name
- PREGFIT (NCT07264231)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
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