Clinical trials: withdrawn
Eye Diseases
Development of an IT Tool Able to Identify Ocular Conditions
The aim of the study is to use machine learning to develop an IT tool able to differentiate between eye conditions analysing corneal biomechanical data.
- Trial name
- NCT05973617
- Testing
- Measurement of corneal biomechanical properties
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aston University
Communication
Emotion Regulation and Burnout Impact on Communication Documentation
This is a single-institution cohort study with two tiers. All participants receive the interventions in Tier 1. Tier 1 is an education study where participants can complete electronic surveys on their pre and post intervention…
- Trial name
- NCT03901547
- Testing
- Communication Skills Training, Profile feedback, Maslach burnout inventory
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Physician's Role, Opinions
Anesthesiologist Perspectives/Opinions/Ethics on Intraoperative/Intraprocedural Code Status and Intraoperative/Intraprocedural Code Status Management Plans
This survey aims to understand anesthesiologists' opinions on intraoperative/intraprocedural code status management (like for example, Do Not Resuscitate (DNR)) in various patient scenarios.
- Trial name
- AnesOpIntraDNR (NCT05883228)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Joseph Hendrix
Dry Eye
Ocular Inflammation in Cataract Patients and Response to Treatment With Xiidra
To determine if the use of Xiidra® reduces ocular surface inflammation in preoperative and postoperative cataract patients.
- Trial name
- NCT04120987
- Testing
- Lifitegrast 5% Ophthalmic Solution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute
COVID-19
A Blood Collection Study to Assess the Immunogenicity of Nationally Authorized Homologous COVID-19 Booster Vaccines Among Adult Vaccinees.
The purpose of this study is to assess the immunogenicity of nationally available pre-defined homologous booster vaccination of a SARS-CoV-2 WHO EUA qualified vaccination in adults aged 18 years and older
- Trial name
- NCT05710289
- Testing
- Immune Responses
- Volunteers
- healthy volunteers welcome
- Sponsor
- SK Bioscience Co., Ltd.
Obstructive Sleep Apnea, Pregnancy Related
Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy
This study will evaluate the effect of treatment of obstructive sleep apnea on insulin sensitivity in pregnant women. Women in their third trimester of pregnancy will be randomized to receive treatment or no treatment for one…
- Conditions
- Obstructive Sleep Apnea, Pregnancy Related, Insulin Sensitivity
- Trial name
- NCT04013399
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barnes-Jewish Hospital
Shoulder Injuries and Disorders
Ultrasling Quadrant Versus Bledsoe ARC Shoulder Brace
Shoulder orthoses are an essential component of both, postoperative care as well as a range of conservative treatment concepts, and thus influence the functional outcome of a wide spectrum of glenohumeral pathologies.
- Trial name
- NCT05960838
- Testing
- Ultrasling® Quadrant, Bledsoe ARC®
- Where
- 2 sites in Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Sarcopenia
Impact of Orally Administered BPM31510 on Mitochondrial Energetics in Older Adults With Sarcopenia
This study is being done to gather data on whether oral supplementation of CoQ10 is enriched in the blood and muscles in older adults with sarcopenia.
- Trial name
- COQ10 (NCT04999488)
- Testing
- BPM31510
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Daytime Cognitive Performance, Sleep
The Impact of Light Intensity in Home Workplaces on Remote Workers' Health
The lockdowns and restrictions associated with the COVID-19 have created a seismic shift in where work is done. Prior to the pandemic, approximately 20% of individuals were working from home while during the pandemic, more than…
- Conditions
- Daytime Cognitive Performance, Sleep, Alertness
- Trial name
- NCT05260801
- Testing
- Bright Lighting
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University
Anesthesia
Superiority of Epidural Placement Technique Using EpiFaith Syringe
The aim of this study is to evaluate the impact of EpiFaith® syringe on the establishment of successful epidural labor analgesia, change of elapsed time for identification of epidural space, and learning curve of CA-1 residents.
- Trial name
- NCT04793373
- Testing
- Syringe
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Infertility
Ovarian Stimulation: Inositol and Melatonin
An efficient protocol of ovarian stimulation is a key part of assisted reproductive technology. In order to obtain the highest oocyte retrieval with no adverse effects, numerous studies have evaluated the efficiency of the…
- Trial name
- NCT01267604
- Testing
- Recombinant FSH (rFSH), rFSH + Inositol + Melatonin
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Weight Reduction
MyFitnessPal Pilot Study
This project is studying whether patients who use MyFitnessPal as an aid to weight loss have more success than patients who are only given traditional medical guidance from the patient's physician.
- Trial name
- NCT05059938
- Testing
- MyFitnessPal user
- Volunteers
- healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Covid19
COVID-19 Trial of the Candidate Vaccine MVA-SARS-2-S in Adults
In this multi-center phase II clinical trial, adults in stable health conditions will be vaccinated twice with either a low dose or high dose of the candidate vaccine MVA-SARS-2-S, or placebo.
- Trial name
- NCT05950776
- Testing
- MVA-SARS-2-S
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pregnancy Related
Daily Step Count and Achieving Goal Gestational Weight Gain
The purpose of this voluntary research study is to determine an optimal step count that aids in achieving the recommended weight gain during pregnancy and to use this count in future studies.
- Trial name
- NCT04605406
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smoking Cessation, Weight Gain
Gut Microbiome and Weight Gain After Smoking Cessation
Investigating the effect of smoking and smoking cessation on the intestinal microbial composition and function. The investigators wish to determine whether the alteration in gut microbiome drives the significant weight gain seen…
- Trial name
- NCT04618705
- Testing
- Smoking Cessation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eran Elinav
COVID-19 Pandemic
A Phase 1, Randomised, Double-blinded, Placebo-controlled, Dose-escalation Study to Evaluate the Safety and Immunogenicity of RH109 as Booster
This is a randomized, double-blinded, placebo-controlled, dose-escalation study to valuate the safety and immunogenicity of RH109 as booster at 2 dose levels for ealthy adults who have received homologous or heterologous…
- Trial name
- NCT05609045
- Testing
- Lyophilized COVID-19 mRNA Vaccine, Sodium chloride
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wuhan Rhegen Biotechnology Co., Ltd.
Depressive Symptoms, Anxiety
COMET India Follow-up Trial
We are evaluating an online single-session intervention for mental health promotion among Indian college students.
- Conditions
- Depressive Symptoms, Anxiety, Happiness
- Trial name
- NCT05138120
- Testing
- Common Elements Toolbox
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Vaccine Decision Making
Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPICC-HPV)
Vaccination against Human Papillomavirus is recommended for adolescent females by the Advisory Committee on Immunization Practices (ACIP), physicians, and many medical organizations, yet uptake of HPV vaccines remains very low.
- Trial name
- EPICC-HPV (NCT03267251)
- Testing
- Vacteens Web app for mobile devices, Standard Usual and Customary HPV Information - CDC pamphlet
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Acute Lung Injury
The Role and Mechanism of Immune Regulation in Acute Lung Injury in Children
Acute lung injury is a highly prevalent disease in children, posing a serious threat to their health and causing economic burden on society and families. It has received high attention.
- Trial name
- NCT05862675
- Testing
- RNA sequencing of blood samples
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Uterine Neoplasms, Endometrial Neoplasms
Colony-Stimulating Factor-1 (CSF-1) and Other Cytokines in Human Endometrial Carcinogenesis
The purposes of this study are the following: 1. To further characterize and quantify both CSF-1 and colony-stimulating factor-1 receptor (CSF-1R) expression from additional tumor specimens, specifically, tumors of high grade and…
- Trial name
- NCT00250770
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
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