Clinical trials: enrolling by invitation
Alzheimer s Disease
TSPO Modulation in AD
The aim of this study is to determine whether pharmacological modulation of TSPO (with XBD173, 90mg twice daily, orally, for 28 days) improves neurovascular coupling (NVC) in AD relative to placebo.
- Trial name
- NCT07191821
- Testing
- XBD173
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Behavior Change Interventions, Work Environment Adverse Effects
From Yearly Checks to Daily Progress: Evaluating Goal Attainment Scaling (GAS) in Systematic Work Environment Management (SAM) Within the Municipal Sector
The goal of this project is to evaluate a practical method for improving systematic work environment management (SAM) by focusing on health-promoting factors rather than identifying risk-factors, and deficiencies.
- Conditions
- Behavior Change Interventions, Work Environment Adverse Effects, Health Factors, Goal Attainment Scaling
- Trial name
- GAS for SAM (NCT06893471)
- Testing
- GAS for SAM
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Aneurysm Cerebral
Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of commercially available MicroVention devices used for the endovascular treatment of intracranial aneurysms (IA) at the direction of…
- Trial name
- CAR (NCT06215105)
- Testing
- Intracranial Aneurysm Devices
- Where
- 5 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Microvention-Terumo, Inc.
Type 2 Diabetes
Assessing Continuous Glucose Monitor Use in Underserved Primary Care Patients
Continuous glucose monitoring (CGM) has demonstrated improved outcomes in both type 1 and type 2 diabetes populations in comparison to traditional methods; however, these devices have not been well studied in underserved adult…
- Trial name
- NCT05766488
- Testing
- Continuous Glucose Monitor (CGM), Self-monitoring Blood Glucose (SMBG)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Arthroscopic Surgical Procedures, Anterior Cruciate Ligament Reconstruction
Incrediwear ACL MCL Arthroscopic Surgery Recovery Study
The goal of this clinical trial is to assess the benefits of using the Incrediwear knee products after anterior cruciate ligament arthroscopic surgery or anterior cruciate ligament and medial collateral ligament (ACL+MCL)…
- Trial name
- NCT06240780
- Testing
- Activated Incrediwear Products
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Oklahoma Joint Reconstruction Institute
Healthy Subjects (HS)
Evaluation of the Effectiveness of Teen Mental Health First Aid in Secondary School Students in Hong Kong
Mental health problems in adolescents are on the rise worldwide especially after COVID -19 pandemic. Early detection and intervention should help to reduce the adverse impact of the mental illness on the adolescent.
- Trial name
- tMHFA-HK (NCT07195890)
- Testing
- A course of teen Mental Health First Aid to be provided to participants
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- TN Foo Centre for Positive Mental Health
Grief, Emotion Regulation
Islamically Integrated Chair-Work for Bereaved Muslims
This study aims to develop and to evaluate the efficacy of an Islamically integrated chair-work intervention designed to assist Muslims experiencing prolonged grief in resolving unfinished business tension.
- Conditions
- Grief, Emotion Regulation, Bereavement
- Trial name
- NCT07193732
- Testing
- Psychotherapy-Empathic Attunement Phase, Psychotherapy - Chair-work intervention phase, Psychotherapy - Cognitive consolidation and spiritually behavioral activation phase
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ibn Haldun University
Cervical Cancer Screening
The Use of a Novel Vaginal Speculum for Cervical Cancer Screening in Sunrise Community Health Patients
The specific aim of this research is to determine if the Bouquet Speculum TM , compared to the existing 2-bladed vaginal speculum, provides better visualization of the cervix, is easier for the provider to use and is more…
- Trial name
- NCT06496295
- Testing
- Vaginal Speculum Exam
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Tooth Discoloration
A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent
The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
- Trial name
- NCT06782087
- Testing
- nano chitosan
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Laparoscopic Colorectal Cancer Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery
Colorectal cancer is the second most common tumor in women and the third most common tumor in men, accounting for approximately 10% of tumors diagnosed and tumor-related deaths worldwide each year.
- Trial name
- NCT06636864
- Testing
- Intrathecal morphine, Intrathecal saline injection, TAPB
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Childhood Obesity, Cardiovascular Disease Prevention
Family Matters Intervention
The proposed study is a 12-month, individual randomized controlled trial (RCT). The main aim of the study is to decrease cardiovascular disease risk (BMI percentile, neck circumference) and improve child diet quality in children…
- Trial name
- NCT02669797
- Testing
- In-home Visits and Food Preparation Activities, Ecological Momentary Intervention, Feedback on Video-recorded Family Meals
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anxiety, Pain
The Effectiveness of Stress Ball in Managing Anxiety and Pain During Prostate Biopsy
This study aimed to determine the effectiveness of stress ball application in the management of anxiety and pain during prostate biopsy.
- Conditions
- Anxiety, Pain, Prostate Biopsy
- Trial name
- NCT07101172
- Testing
- stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hitit University
Adult Caregivers of Individuals With TSC, Tuberous Sclerosis Complex (TSC)
TANDem-2: Closing the Gap to Interventions for TAND
The goal of this pilot study is to determine the feasibility, acceptability and impact of a brief behavioral intervention - the "Well-Beans for Caregivers" program, for adult caregivers of individuals with tuberous sclerosis…
- Trial name
- TANDem-2 (NCT06879665)
- Testing
- Well-Beans for Caregivers Program
- Where
- 2 sites in United States, Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Airway Ultrasound Indices, Clinical Airway Assessment
Airway Ultrasound Indices for Prediction of Difficult Laryngoscopy in Pediatric Patients
The goal of this observational study is to compare the airway ultrasound indices and the preoperative clinical airway assessment concerning the difficult laryngoscopic view in paediatric patients undergoing elective surgery under…
- Trial name
- NCT07185516
- Testing
- Airway ultrasound indices, Clinical airway assessment
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain Syndrome, Emotional Stress
The Effects of Jing Si Herbal Tea on Physical and Psychological Symptoms in Peripheral Blood Hematopoietic Stem Cell Donors
This study aim to explore the impact of Jing Si Herbal Tea on pain and emotional stress in peripheral blood stem cell donors.
- Trial name
- NCT06141902
- Testing
- Jing Si Herbal Drink
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
TED
Phase I Clinical Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics of NTB003 in Healthy Participants
This study is a randomized, double-blind, dose-escalation Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetic/pharmacodynamic characteristics of NTB003 injection in healthy volunteers.
- Trial name
- NCT07182552
- Testing
- NTB003
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
Mental Distress, Mental Resilience
Digital Care Programs for Mental Health
The purpose of this study is to create a research repository, composed of data collected over the course of digital care programs for mental health distress delivered by Sword Mind to individuals.
- Trial name
- NCT07183085
- Testing
- Intervention
- Where
- United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Sword Health, SA
Stress
Vital@Work: an Intervention for Prevention of Mental Health Complaints at Work
The objective of the current study, Vital@Work, is to keep employees in the Netherlands vital on the long term by preventing work-related mental health problems.
- Trial name
- NCT06445101
- Testing
- Participatory Approach
- Where
- 4 sites in Netherlands
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Catheter Blockage
UROtainer for Bladder Catheter Maintenance, Infection Prevention and Quality of Life
The purpose of the current study is to investigate whether catheter flushing with Uro-Tainer® with citric acid and Uro-Tainer® Polihexanide can: Reduce catheter changes due to incrustation and blockage.
- Trial name
- UROBIQ (NCT05775614)
- Testing
- UroTainer®, Saline
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
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