Clinical trials: sponsored by Ain Shams University
Mandibular Distal-extension Prostheses
Periodontal Health and Patient Satisfaction of CAD/CAM Fiber-Reinforced vs. PFM Attachments in Distal Extension RPDs
This randomized clinical trial aims to assess periodontal health and patient satisfaction in mandibular distal extension removable partial dentures using CAD/CAM fiber-reinforced composite versus porcelain-fused-to-metal…
- Trial name
- NCT06871020
- Testing
- Mandibular removable partial denture retained on OT extracoronal attachment made from fiber-reinforced composite resin, Mandibular removable partial denture retained on OT extracoronal attachment made from porcelain-fused to metal
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Serratus Anterior Plane Block
Comparison of the Analgesic Efficacy of Ultrasound-guided Retrolaminar Block Versus Serratus Anterior Plane Block in Patients Undergoing Radical Mastectomy
All patients will be taught how to interpret the visual analogue scale (VAS) of 0 to 10 with 0 experiencing no pain and 10 being the worst pain imaginable.
- Trial name
- NCT07649837
- Testing
- Serratus Anterior Plane Block (SAPB) group, Retrolaminar block group
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant
Peri-implant Tissue Changes Using Dual Zone Concept With Connective Tissue Graft Versus Concentrated Growth Factor
Tooth extraction not only alters the bony architecture of the alveolar ridge, but it also has an impact on the surrounding soft tissues.
- Conditions
- Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant, Immediate Implant Placement
- Trial name
- NCT06728696
- Testing
- Immediate implant with with dual zone technique using concentrated growth factor graft., Immediate implant with dual zone technique using connective tissue graft.
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Major Depressive Disorder, MDD
Efficacy of Statins Among Major Depressive Disorder
The goal of this clinical trial is to learn if drug Rosuvastatin 10 mg works to treat MDD in adults. It will also learn about the safety of Rosuvastatin 10 mg .The main questions it aims to answer are: Does Rusovastatin lower the…
- Trial name
- NCT06698666
- Testing
- Rosuvastatin 10 mg tablet., Sertraline Pill
- Where
- Egypt
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Altered Passive Eruption of Teeth
The Effect of Using Two Different Suturing Techniques on Free Gingival Marginal Stability
Gummy smile is one of the major esthetic problems nowadays; it is due to several causes that either dental or skeletal. Etiology of the gummy smile is altered passive eruption, vertical maxillary excess, different gingival…
- Trial name
- NCT04219436
- Testing
- vertical mattress suturing technique, figure of eight suturing technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension on Induction
Carotid Artery Corrected Flow Time and Respiratory Variation of Blood Flow Peak Velocity for Prediction of Hypotension After Induction of General Anaesthesia in Adult Patients With Chronic Liver Disease
Baseline Measurements For the ultrasound parameters, it is the average of three readings In supine position . The investigators will continuously monitoring during induction and 10 minutes after.
- Trial name
- NCT07370103
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession, Localized
Bi-layer Collagen Membrane Versus Subepithelial Connective Tissue Graft in the Treatment of Localized Gingival Recession
The goal of this clinical trial is evaluation of the change in depth and width of gingival recession in terms of gingival thickness and esthetics, and evaluation of patient satisfaction in terms of postoperative pain and final…
- Trial name
- NCT07162207
- Testing
- Pinhole surgical technique
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post Operative Pain, Acute
Postoperative Pain After Dexamethasone Injection by Two Techniques in Irreversible Pulpitis
The aim of this randomized clinical trial to evaluate the effect of dexamethasone in two different techniques on postoperative pain by dividing patients randomly into three groups: Group I: buccinator injection of dexamethasone.
- Trial name
- Dex/postop (NCT07755306)
- Testing
- dexamethasone 8mg
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Orthodontic Aligners
The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial.
The aim of this study is to evaluate the accuracy of clear aligners on the amount of the maxillary molar distalization.
- Trial name
- Aligner (NCT06330571)
- Testing
- Molar distalization by aligners with attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Knee Arthroscopic Surgery, Nerve Block
TIPS Block vs. IV Analgesia for Postoperative Pain After Knee Arthroscopy
In this study participants are aiming to compare triple injection peri-sartorius (TIPS) block versus intravenous analgesia for postoperative analgesia after knee arthroscopy regarding efficacy of pain relief and early ambulation
- Trial name
- NCT07046390
- Testing
- nerve block with bupivacaine 0.25%, No intervention
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fasting
Preoperative Ultrasound Evaluation of Fasting Residual Gastric Volume in Patients With Previous Sleeve Gastrectomy
Preoperative US assessment of residual gastric volume in both; patients with previous laparoscopic sleeve gastrectomy and those without history of bariatric surgeries, undergoing elective laparoscopic cholecystectomy, aiming to…
- Trial name
- NCT06543615
- Testing
- Ultrasonography
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries in Children
Evaluation of the Antibacterial Effect of Probiotics on Cariogenic Bacteria in Children
This randomized controlled clinical trial aims to evaluate the effect of oral probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei on cariogenic bacteria (Streptococcus…
- Trial name
- NCT07904221
- Testing
- Probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei, Xylitol-based moisturizing lozenges
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Participants
the Effect of Different Background Color and Skin Tone on the Accuracy of Auricular Scanning
The goal of this study is to find the best miss and match background color around an ear when taking scans for it , the investigators will recruit participants of three different skin tone and will scan their ear three times; one…
- Trial name
- NCT07108946
- Testing
- Black background, White background, Participant own skin as a background
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- yasmine Elsherbeeny
Patients Diagnosed With Persistent Apical Periodontitis in Maxillary Anterior Regions Require Endodontic Microsurgery
Bone-Bioactive Liquid as an Adjunct in Endodontic Surgery
This randomized controlled clinical trial will include patients indicated for endodontic microsurgery due to persistent periapical lesions. Participants will be randomly allocated into two groups.
- Trial name
- NCT07879482
- Testing
- Bone Bioactive Liquid in endosurgery, conventional endodontic surgery
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bruxism, Sleep Bruxism
Low-Level Laser Therapy Versus Occlusal Splint Therapy for Bruxism in Children
Many children grind or clench their teeth, especially during sleep. Doctors call this bruxism. It can wear down teeth and cause jaw pain. This study compared two treatments for bruxism in children.
- Trial name
- NCT07865845
- Testing
- Low-Level Laser Therapy (LLLT), Occlusal Splint
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries Class II
Evaluation of Clinical Success of Bulk Fil Composite Versus Highly Viscous Glass Ionomer in Primary Class II Molars
evaluate the clinical performance of EQUIA Forte ® ( a HVGIC) and Plafique® Bulk Flow composite resin when placed in class II cavities in primary molars.
- Trial name
- NCT06235489
- Testing
- Palfique Bulk Flow
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia Residents, Critical Care Staff
Relation Between Workload and Coping Strategy Among Newly Recruited Anesthesia and Critical Care Residents
This survey aims to find the relation, if any, between the perceived work load and the adopted coping strategy among newly recruited anesthesia and critical care residents.
- Trial name
- NCT07873788
- Testing
- NASA-TLX to assess the perceived work load
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nephrotoxicity, Acute Kidney Injuries
Rutin and Ascorbic Acid for Prevention of Vancomycin-Induced Nephrotoxicity in Adult Patients" - a Clinical Trial Protocol Evaluating Whether Combined Rutin/Vitamin C Supplementation Reduces Kidney Toxicity From Vancomycin, Compared to Vitamin C Alone and Control.
Background: Vancomycin, a key antibiotic for MRSA infections, frequently causes nephrotoxicity (kidney damage) via oxidative stress, especially at the higher doses and longer durations now recommended.
- Trial name
- NCT07873372
- Testing
- Rutin + Ascorbic Acid (RUTA C60®), Ascorbic Acid (C-Retard®)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Keratoplasty, Regional Block
Comparative Study Between Dexamethasone Versus Magnesium Sulfate in Medial Episcleral Technique in Keratopalsty Surgeries
The aim of this work is to compare between the effects of addition of Dexamethasone versus magnesium sulfate to local anesthetic mixture in medial episcleral technique in keratoplasty operations
- Trial name
- NCT07847489
- Testing
- Bupivacaine hydrochloride, Dexamethasone, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University