Clinical trials: sponsored by Region Stockholm
Coronary Artery Disease, Arterial Stiffness, Blood Pressure
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018.
- Conditions
- Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency
- Trial name
- SCAPIS-ReEx (NCT07476703)
- Testing
- Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography
- Where
- Sweden
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Multiple Sclerosis
Simultaneous T2-FLAIR and T1 Brain MRI With ENRAGED FLAIR in Multiple Sclerosis
This study will evaluate a new brain MRI technique called ENRAGED FLAIR in patients with multiple sclerosis. MRI is central in the diagnosis and follow-up of multiple sclerosis because it can show inflammatory lesions in the…
- Trial name
- ENRAGED FLAIR (NCT07687693)
- Testing
- ENRAGED FLAIR MRI
- Where
- Sweden
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Student Education
Systematic Evaluation of Psychotherapy Training: Supervision, Student Learning, and Patient Outcomes
The project is a longitudinal observation study that aims to systematically evaluate selected parts of the material collected within the framework of the psychotherapy training conducted at the Center of Psychotherapy Education…
- Trial name
- NCT06105502
- Testing
- Psychotherapy education
- Where
- Sweden
- Volunteers
- 417 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Endometriosis
Endoexpedition - Use of a Serious Game to Deliver Patient Information and Decision Aid for Individuals With Endometriosis.
Endometriosis is a chronic disease that can negatively affect quality of life, daily functioning, fertility, and psychological well-being.
- Trial name
- NCT07758946
- Testing
- EndoExpedtion Serious game, Standard Written Patient Information
- Where
- 4 sites in Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cognitive Decline, Cognitive Impairment
METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for Dementia
Dementia is the main cause of disability in older adults, currently affecting about 50 million people world-wide with this number estimated to triple in the next 30 years.
- Conditions
- Cognitive Decline, Cognitive Impairment, Dementia
- Trial name
- MET-FINGER (NCT05109169)
- Testing
- FINGER 2.0 multidomain lifestyle-based intervention, Self-guided multidomain lifestyle intervention
- Where
- 3 sites in Finland, Sweden and 1 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cancer
Evaluation of a Psychosocial Support Model for Adolescents and Young Adults Newly Diagnosed With Cancer
Rational: Adolescents and young adults (AYAs) newly diagnosed with cancer is a small but vulnerable group with many psychosocial needs persisting for a long time.
- Trial name
- NCT06979843
- Testing
- A psychosocial model
- Where
- 2 sites in Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Paraphilic Disorders, Sexual Addiction
Paraphilic Disorders and Other Conditions With Risk for Sexual Violence: a Case-control Study
The goal of this case-control study is to compare clinical characteristics in help-seeking individuals with paraphilic disorders or sexsomnia (sexual behaviors during sleep- a diagnosis in the American Psychiatric Association's…
- Conditions
- Paraphilic Disorders, Sexual Addiction, Parasomnia
- Trial name
- NCT05861752
- Testing
- Treatment as usual
- Where
- Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Metabolic Disease, Mitochondrial Diseases
Genetic Diagnosis in Inborn Errors of Metabolism
Inborn Errors of metabolism comprise a large number of rare conditions with a collective incidence of around 1/2000 newborns. Many disorders are treatable provided that a correct diagnosis can be established in time, and for many…
- Conditions
- Metabolic Disease, Mitochondrial Diseases, Epilepsy in Children, Epilepsy
- Trial name
- NCT06376279
- Testing
- IEM-EP
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Family Conflict, Family Relations
Parent Web - Support for Families With Young People
To test an online parent training program. Relative to a randomized wait-list control group, those in the Parent Web (PW) will show benefits on well-being, parenting, stress, youth mental health.
- Conditions
- Family Conflict, Family Relations, Family Dysfunction
- Trial name
- PWS2 (NCT06533735)
- Testing
- Parent Web
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Knee Osteoarthritis
Investigating the Role of Motivational Interviewing in Swedish Patients Undergoing Knee Arthroplasty
Knee arthroplasty is a successful surgical treatment for end-stage osteoarthritis. Most patients are satisfied with the result, however, 10% of the patients have remained dissatisfied over the last decades despite the advantages…
- Trial name
- NCT05940246
- Testing
- Motivational Interviewing
- Where
- Sweden
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Sarcoidosis
Immunological Mechanisms in Sarcoidosis
There is no cure for the inflammatory disease sarcoidosis. Virtually any part of the body can be affected but most often the lungs and lymph nodes.
- Trial name
- NCT06576505
- Testing
- peripheral blood sampling, bronchoscopy, upper airway and faeces sampling
- Where
- Sweden
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Mental Health Issue, Insomnia
Promoting Teenage Sleep for Improved Mental Health and School Performance
The overall aim of this project is to evaluate the effectiveness of two school-based programs that have the potential to promote adolescent sleep and prevent future depressive symptoms.
- Conditions
- Mental Health Issue, Insomnia, Depression, Anxiety
- Trial name
- TeenSleep (NCT06306092)
- Testing
- Sleep on Schedule, Technology restriction
- Where
- Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Kristianstad University
Opioid-Related Disorders, Narcotic-Related Disorders
Safe Prescription of Opioids in Primary Care
Opioid analgesics are commonly prescribed addictive narcotics intended for the treatment of pain. Inappropriate prescription of opioids in quantities and for conditions which lack clinical evidence contributes to the risk of…
- Conditions
- Opioid-Related Disorders, Narcotic-Related Disorders, Addiction
- Trial name
- NCT05577026
- Testing
- Educational intervention and prescription feedback, General information on treatment guidelines
- Where
- Sweden
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Brain Tumor, Childhood Cancer
Biomarkers of Brain Injury in Children With Brain Tumors
The goal of this observational study is to identify biomarkers of treatment-induced brain injury in children treated for primary brain tumors.
- Conditions
- Brain Tumor, Childhood Cancer, Childhood Brain Tumor
- Trial name
- BiomarkCBT (NCT07381959)
- Where
- Sweden
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Chronic Kidney Diseases
Electronic Decision-support System to Improve Detection and Care of Patients With Chronic Kidney Disease in Stockholm
One in 10 adults in Region Stockholm have chronic kidney disease (CKD), which dramatically increases healthcare costs and the risk of medication errors or adverse health outcomes, including cardiovascular disease and death.
- Trial name
- ALMA-CKD (NCT06386172)
- Testing
- Clinical decision support trigger
- Where
- Sweden
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Endometriosis
Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate/Severe Endometriosis Patients
This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation.
- Trial name
- NCT07182643
- Testing
- Endometrial fluid, Endometrial biopsy, Follicular fluid
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Clubfoot, PBS
Video Documented PBS-Score in Children With Clubfoot
Evaluate agreement and inter-rater reliability of PBS-score assessments based on video documented material.
- Trial name
- PEVA (NCT06033638)
- Testing
- Score assessment
- Where
- Sweden
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Vestibular Disorder
Vestibular Function and Motor Development in Small Children
Infants and toddlers with and without vestibular impairment will be tested blinded by pediatric physiotherapist with different age adequate motor scales in order to find out pathological motor patterns specifically associated to…
- Trial name
- NCT07079488
- Testing
- Motor proficiency scales
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Superior Canal Dehiscence Syndrome, Vestibular Disorder
Diagnostic Precision Study on Vibration Induced Nystagmus Test for SCDS by Ortofone B250 Skull Vibration Protocol
to study the videonystagmography response to a bone conducted vibration on the mastoid by B250 bone transducer in patients affected by vestibular loss, Menieres disease and Superior Semicircular Canal Dehiscence Syndrome vs…
- Trial name
- VIN by B250 (NCT05967065)
- Testing
- vibration induced nystagmus test
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet