Clinical trials: Aerobic Exercise
Mild Cognitive Impairment
SYNchronizing Exercises, Remedies in Gait and Cognition at Home (SYNERGIC@Home)
Background: Prevention of Alzheimer's Disease and Related Dementias (ADRDs) may be possible for persons with subjective (SCI) or mild cognitive impairment (MCI), or normal cognition and risk factors.
- Trial name
- SYNERGIC@Hom (NCT04997681)
- Testing
- Combined Aerobic Exercise and Resistance Training (AE + RT), Cognitive Training (NeuropeakTM), Control Cognitive Training of Website Searching and Video Watching (WS+V)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of New Brunswick
Sedentary Lifestyle, Physical Activity
Physical Activity and Sedentary Behavior Change; Impact on Lifestyle
Diabetes Prevention Program translational efforts, such as the Group Lifestyle Balance Program (GLB), have been shown to be effective in reducing weight and modifying diabetes and CVD risk factors in a variety of diverse…
- Trial name
- NCT02467881
- Testing
- Physical Activity Increase (GLB-MOD), Sedentary Time Decrease (GLB-SED), 6-month delayed (DELAYED)
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Pittsburgh
End-stage Renal Disease
Physical Fitness/Training and Inflammatory Immune Responses in Patients With End-stage Renal Disease
The end-stage renal disease (ESRD) leading two causes of death are cardiovascular diseases and sepsis. Exercise improves low physical fitness, available research concerning its effect on the pro-/anti-inflammatory immune response…
- Trial name
- NCT04949919
- Testing
- aerobic training by a cycle ergometer and Biodex system 4 pro
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Aortic Valve Stenosis
Exercise-based Cardiac Rehabilitation in Patients With Aortic Stenosis After Transcatheter Aortic Valve Implantation
Aortic valve stenosis (AS) is the most common valve disease among older individuals. In symptomatic AS, mortality is high, and the only treatment that improves prognosis and survival is transcatheter aortic valve implantation…
- Trial name
- TAVI (NCT06283940)
- Testing
- Physiotherapist-led exercise based cardiac rehabilitation (PT-X)
- Where
- Sweden
- Volunteers
- 135 people
- Sponsor
- Vastra Gotaland Region
Schizophenia Disorder, Schizoaffective Disorder
Exercise and Olanzapine-samidorphan
This is a single site trial in 30 patients with schizophrenia, schizoaffective, or bipolar I/II/NOS disorder in which all participants will receive eight weeks of olanzapine and samidorphan (Olz/Sam) plus four weeks of aerobic…
- Conditions
- Schizophenia Disorder, Schizoaffective Disorder, Bipolar Disorder I or II, Bipolar Disorder NOS
- Trial name
- NCT06740890
- Testing
- Olanzapine-samidorphan + exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Mild Cognitive Impairment, Cognitive Disorders
Mild Cognitive Impairment, Buddy Supported Exercise/ My Buddy Study
This is a small pilot trial of a 5 month aerobic exercise intervention in participants with MCI (n=20) to begin to compare the effects of randomization to use an exercise buddy or to exercise without an assigned buddy.
- Trial name
- NCT01561820
- Testing
- 5-month aerobic exercise intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University
Body Composition, Physical Function
Lifestyle Intervention to Improve Muscle Function in Older Adults
The goal of this randomized controlled two-arm trial is to determine the effect of a diet and exercise intervention for 12 weeks on body composition, muscle function, and energy balance in 80 adults aged 50 years and over with…
- Conditions
- Body Composition, Physical Function, Energy Balance
- Trial name
- NCT07597980
- Testing
- Structured nutrition plan, Typical or usual diet, Supervised Exercise
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Pennington Biomedical Research Center
Physical Disability
Wheelchair User Physical Activity Training Intervention to Enhance Cardiometabolic Health
The goal of the study is to improve cardiometabolic health outcomes for wheelchair users and identify strategies for achieving sufficient physical activity intensity during bouts of structured physical activity.
- Trial name
- WATCH (NCT06013046)
- Testing
- Intensity-controlled physical activity training (IPAT), Education and Access (EA)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Washington University School of Medicine
Multiple Sclerosis, Stroke
Short Arm Human Centrifuge Therapeutic Training and Rehabilitation (GRACER1)
The study is a single blind randomized controlled trial (RCT) designed to examine the benefit of a short arm human centrifuge intervention program (SAHC) combined with exercise, compared to a standard of care (SOC) rehabilitation…
- Conditions
- Multiple Sclerosis, Stroke, Pulmonary Disease, Chronic Obstructive, Aged
- Trial name
- GRACER1 (NCT04369976)
- Testing
- ARTIFICIAL GRAVITY COMBINED WITH EXERCISE
- Where
- Greece
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Greek Aerospace Medical Association and Space Research
Heart Failure, Ventricular Function, Left
Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction
Exercise is essential in cardiac rehabilitation for heart failure patients.Aerobic training and resistance training are both recommended.
- Trial name
- ERFOCARD (NCT07118410)
- Testing
- Application of a vascular restriction device during resistance training
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Rheumatoid Arthritis
Targeted Remotely-delivered Anti-inflammatory Interventions With Exercise for Rheumatoid Arthritis
The primary objective of this study is to assess the feasibility of an intensive, remotely-delivered, combined aerobic and resistance training exercise program for patients with Rheumatoid Arthritis (RA) and to collect data to…
- Trial name
- TRAINERa (NCT06841562)
- Testing
- TRAINERa intensive exercise training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Psychological Distress, Anxiety Symptoms
Exer-WAPA Project: Physical Exercise on Women's Affective and Physical HeAlth
The Physical Exercise on Women's Affective and Physical HeAlth (Exer-WAPA) project is a randomized controlled trial (RCT) designed to evaluate the effects of a supervised, group-based exercise program incorporating…
- Conditions
- Psychological Distress, Anxiety Symptoms, Depression Symptoms
- Trial name
- Exer-WAPA (NCT07466979)
- Testing
- Supervised Concurrent Exercise (Exer-WAPA)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Glucose Control
The Effect of High-Intensity Short-Duration Exercise Versus Moderate-Intensity High-Volume Exercise on Glucose Control
This study will be conducted as a prospective, randomized crossover trial evaluating non-diabetic and pre-diabetic adults ($n=12$) continuously monitored with Dexcom G7 continuous glucose monitors over an 11-day period.
- Trial name
- NCT07829042
- Testing
- High Intensity Interval Training, Moderate Intensity aerobic training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Exercise
High-Intensity Functional Training (HIFT) vs Moderate-Intensity Continuous Training (MICT) in College Students
The purpose of this study is to compare two types of exercise programs in college students: high-intensity functional training and moderate-intensity continuous training.
- Trial name
- NCT07745270
- Testing
- High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Miami
Vestibular Disorder
Vestibular Treatment in Adolescents Following Sport Related Concussion
Each year, nearly 2 million children and adolescents have a sport-related concussion (SRC) in the U.S., but 57% of them do not receive appropriate clinical care following their injury.
- Trial name
- NCT03555370
- Testing
- Vestibular Exercise Intervention, Standard of Care
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Heart Failure
Effect of Upper Extremity Aerobic Exercise Training on Exercise Capacity Patients With Chronic Heart Failure
Heart failure is a cardiac structural or functional disorder that, despite normal filling pressures, leads to inability to deliver enough oxygen to meet the metabolic needs o tissue.
- Trial name
- NCT03675113
- Testing
- Upper extremity aerobic exercise, Control Group
- Where
- 2 sites in Turkey (Türkiye)
- Sponsor
- Gazi University
Spinal Cord Injuries
Functional Interval Training for People With Spinal Cord Injury and Their Care Partners
Functional Interval Training for People with Spinal Cord Injury and Their Care Partners (SCI-FIT) aims to address barriers to physical activity for people with spinal cord injury and their care partners.
- Trial name
- SCI-FIT (NCT05221723)
- Testing
- High Intensity Interval Exercise Training Group
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Enhanced External Counterpulsation (EECP), Acute Myocardial Infarction (AMI)
Effect of Enhanced External Counterpulsation
This study evaluated the efficacy and safety of enhanced extracorporeal counterpulsation for cardiac rehabilitation in patients after DCB for acute myocardial infarction.
- Conditions
- Enhanced External Counterpulsation (EECP), Acute Myocardial Infarction (AMI), Drug-coated Balloon, Cardiac Rehabilitation
- Trial name
- EECP (NCT06877390)
- Testing
- conventional drug and exercise rehabilitation, EECP-based rehabilitation regimen
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chongming Hospital Affiliated to Shanghai University of Health & Medicine Sciences
Colorectal Cancer (Diagnosis)
Effects of a WhatsApp-assisted Prehabilitation for Patient Undergoing Elective Colorectal Cancer Surgery
The goals of this study is to evaluate the feasibility and the effects of a WhatsApp-assisted prehabilitation for colorectal cancer patients undergoing elective surgery.
- Trial name
- NCT07376668
- Testing
- Intervention, Standard care
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Frailty, Falls
Virtual Reality-Based vs Traditional Physiotherapy for Balance, Frailty, and Fall Prevention in Adults Aged 45 Years and Older
This study will compare two exercise-based rehabilitation programs to improve balance and reduce fall risk in adults aged 45 years and older who have had at least one fall in the past year or have balance problems.
- Conditions
- Frailty, Falls, Balance Deficits, Mobility Limitations
- Trial name
- NCT07322861
- Testing
- Virtual Reality-Based Training Program, Physiotherapy Exercise Program
- Volunteers
- 80 people
- Sponsor
- Umm Al-Qura University
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