Clinical trials: Bupivacaine
Pain, Postoperative
The Effect of Bilateral Erector Spina Plane Block on Postoperative Analgesia in Cesarean Section Under SpinalAnaesthesia
Acute pain after cesarean section (SC) can be variable. Untreated pain can affect patients' life quality. Currently regional nerve blocks are frequently used as a part of multimodal analgesia.
- Trial name
- NCT05695625
- Testing
- Spinal anesthesia + bilateral erector spine plane block, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ankara University
Post-thoracotomy Pain Syndrome
The Effect of Ultrasound Guided Superficial, Deep Serratus Plane Blocks and Thoracic Epidural in Thoracotomy
Pain after thoracotomy is known to be sever acute pain that is resulted from retraction, resection or fracture of ribs .This pain increases post operative morbidity and if not properly managed peri-operatively, chronic post…
- Trial name
- NCT04189120
- Testing
- Thoracic epidural analgesia , superficial serratus plane block and deep serratus plane block
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Pain, Postoperative, Thoracic
Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures
The study is comparing the difference between erector spinae block and surgeon infiltration after VATS (Video Assisted Thoracoscopic Surgery).
- Conditions
- Pain, Postoperative, Thoracic, Acute Pain
- Trial name
- NCT03859635
- Testing
- Liposomal Bupivacaine, Bupivacaine, 0.25%, Bupivacaine, 0.5%
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Indiana University
Delirium, Anesthesia
Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position
Postoperative delirium is an acute mental syndrome that is caused by diffuse cerebral dysfunction resulting from the action of predisposing and precipitating factors acting together.
- Trial name
- NCT03572517
- Testing
- Subarachnoid block, Spinal morphine
- Where
- Brazil
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- AC Camargo Cancer Center
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cardiac Output
The Effect of Left Uterine Displacement on Parturient Cardiovascular System
The aim of the study is to investigate the effect of different angles of lateral tilt on the maternal hemodynamics before and after spinal anesthesia
- Trial name
- NCT02828176
- Testing
- electric cardiometry, IV line insertion, spinal anesthesia ( subarachnoid block )
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Fracture
Single Shot Versus OnQ Pump in Extremity Fractures
Peripheral nerve blocks have been well studied in the literature with generally good results for controlling post operative pain following orthopaedic surgery. Regional anesthesia has many benefits.
- Trial name
- NCT02280291
- Testing
- Ankle SSB, Ankle OnQ, DR SSB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Nephrectomy, Lung Diseases
Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients
Patients with respiratory disease have an increased risk of developing complications perioperatively. The use of regional anesthesia decreases this risk with better postoperative outcome.
- Conditions
- Nephrectomy, Lung Diseases, Anesthesia
- Trial name
- NCT03324490
- Testing
- Thoracic Spinal Anesthesia, Thoracic Epidural Anesthesia, Bupivacaine 0.5% (hyperbaric)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nazmy Edward Seif
Intraoperative Analgesia, Postoperative Pain
PECS II Versus ICBN Block Plus SCNB for AV Fistula Creation in CRF Patients
Brachial plexus block (BPB) is often utilized for proximal arm arteriovenous access creation. However, the medial upper arm and axilla are often inadequately anesthetized, as the Intercostobrachial nerve (which provides sensory…
- Trial name
- NCT04988776
- Testing
- ultrasUltrasound-guided Intercostobrachial nerve block supplemental to supraclavicular block with 30 ml 0.25% bupivacaine (15 ml 0.5% bupivacaine will be added to 15 m, ultrasound-guided pectoral nerves block type II supplemental to supraclavicular block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Abdominal Pain, Shoulder Pain
Pain Management of Emergency Laparoscopic Cholecystectomy in Patients With Acute Cholecystitis
Patients diagnosed with acute cholecystitis benefit from emergency laparoscopic cholecystectomy (LC). Patients who had emergency LC showed improvement in quality of life in one month compared to those treated.
- Conditions
- Abdominal Pain, Shoulder Pain, Satisfaction, Complication
- Trial name
- NCT03708874
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pain Management
Enhanced Pain Relief With Ultrasound Guided Combined Submaltifidus and Sacroiliac Joint Injection
Sacroiliitis is not the same as SI joint dysfunction. Sacroiliitis is specific to an inflammatory processes present in the SI joint and the pain sensed is a direct result of those inflammatory processes, whereas sacroiliac joint…
- Trial name
- NCT07137806
- Testing
- sacroiliac joint injection, combined sacroiliac joint injection and sub maltifidous plane block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Tanta University
Postoperative Pain
Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery
Erector spinae plane block (ESPB) is a novel regional block technique that was proven to have superior outcomes in relieving postoperative pain in colorectal surgeries.Ketamine enhances the impact of local anaesthetics by…
- Trial name
- NCT06007378
- Testing
- Bupivacaine and ketamine, Bupivacaine and transdermal fentanyl patch, Bupivacain
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Retrograde Intrarenal Surgery
General Versus Spinal Anesthesia in RIRS
The impact of anesthesia type on Retrograde Intrarenal Surgery (RIRS) outcomes remains a subject of ongoing debate. Several studies have compared general anesthesia (GA) and spinal anesthesia (SA) in endourological procedures…
- Trial name
- NCT07664384
- Where
- Egypt
- Volunteers
- 252 people
- Sponsor
- South Valley University
Diaphragm Paralysis
The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function
Peripheral nerve blocks are used to provide post-operative pain relief. Nerve blocks in the neck, in the interscalene area, provide pain relief after shoulder surgery but can cause temporary weakness or paralysis of the…
- Trial name
- NCT01429584
- Testing
- interscalene nerve block with 0.25% bupivacaine, interscalene block with 0.125% bupivacaine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Upper Extremity Injury
Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone
Upper-extremity regional anesthetic techniques, using brachial plexus blockade, have been shown to reduce adverse effects related to opioid administration, improve patient satisfaction, and provide significantly improved…
- Trial name
- NCT06356415
- Testing
- Bupivacaine injection, Bupivacaine+ Dexamethasone+ Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Breast Cancer, Modified Radical Mastectomy
Ultrasound-Guided PEC I vs SAP Block for Postoperative Analgesia in Modified Radical Mastectomy
This randomized double-blind controlled clinical trial was conducted to compare the analgesic efficacy of ultrasound-guided Pectoral Nerve Block versus Serratus Anterior Plane Block in female patients undergoing Modified Radical…
- Conditions
- Breast Cancer, Modified Radical Mastectomy, Pectoral Nerve Blocks, Serratus Anterior Plane Block
- Trial name
- PECS I vs SAP (NCT07388238)
- Testing
- Ultrasound-Guided Pectoral Nerve Block (PECS I), Ultrasound-Guided Serratus Anterior Plane Block (SAPB)
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Ain Shams University
Postoperative Pain, Craniotomy
REDUCE Trial: Perineural Dexamethasone on Scalp Nerve Blocks
Pain is common in the first 2 days after major craniotomy. Inadequate analgesia may lead to an increased risk of postoperative complications.
- Conditions
- Postoperative Pain, Craniotomy, Dexamethasone, Scalp Nerve Blocks
- Trial name
- NCT04648358
- Testing
- Bupivacaine, Dexamethasone combined with bupivacaine
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain
Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the standard surgical treatment for gallbladder stones; however, the origin of pain after LC is multifactorial and complex in nature.
- Trial name
- NCT07670052
- Testing
- Fentanyl, Ketamine
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hip Fractures, Supra-inguinal Fascia Iliaca Block
Preoperative Supra-inguinal Fascia Iliaca Block for Positioning Analgesia in Hip Fracture Patients Undergoing Spinal Anesthesia
The goal of the clinical trial is to learn if preoperative Superficial Inguinal Fascia Iliaca (SIFI) block works to reduce pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures, Supra-inguinal Fascia Iliaca Block, Spinal Anesthesia
- Trial name
- NCT07556614
- Testing
- Isobaric bupivacaine 0.5%
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Ghurki Trust and Teaching Hospital
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