Clinical trials: CPAP
Insomnia, Obstructive Sleep Apnea
The Impact of CBT-i on CPAP Therapy Use and Drop Outs in OSAS Patients With Insomnia.
Patients follow the fully standard sleep test according to the normal procedure. This means that they undergo a polysomnography and fill in a questionnaire.
- Conditions
- Insomnia, Obstructive Sleep Apnea, Cognitive Behavioral Therapy, Continuous Positive Airway Pressure
- Trial name
- NCT04306835
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pneumonia, Bronchoalveolar Lavage
HCAPPED I: HCAP-Pcr in Emergency Department
Prospective Observational Study (on Diagnostic Procedure) - Single-Center, Non-Profit. A pilot study will be conducted on a prospective cohort of patients with HCAP (Healthcare-Associated Pneumonia).
- Conditions
- Pneumonia, Bronchoalveolar Lavage, Antimicrobial Treatment, Sputum
- Trial name
- HCAPPED-I (NCT06506617)
- Where
- Italy
- Volunteers
- 93 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Chronic Pain, Obstructive Sleep Apnea
Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea and Chronic Pain
The bidirectional link between sleep and pain is a widely accepted concept. While there has been much focus on this in recent years, studies investigating obstructive sleep apnoea (OSA) and chronic pain are still not very common…
- Trial name
- NCT06834724
- Testing
- Standard OSA care
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Kidney Insufficiency, Sleep Apnea
Effect of CPAP in the Worsening of Renal Function in Early Stages of Chronic Kidney Disease (CKD)
Objectives: Evaluate the effect of CPAP to reduce the progression of chronic kidney disease or CKD (the decline of glomerular filtration rate is ≥ 30%) in patients with early-stage renal disease and sleep apnea syndrome (OSAS).
- Trial name
- Renas (NCT03319888)
- Testing
- CPAP, conservative treatment
- Where
- Spain
- Volunteers
- 700 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Chronic Respiratory Failure
Database of Patients Treated With Respiratory Support
An observatory of patients registered in 22 local homecare associations in France, for respiratory diseases, with annual data update.
- Trial name
- observatory (NCT01181869)
- Testing
- oxygen
- Where
- France
- Volunteers
- 120,000 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Obstructive Sleep Apnea
Autonomic Function in Obstructive Sleep Apnea
The purpose of this study is to determine if obstructive sleep apnea (OSA) causes autonomic dysfunction independent of its effects on hyperglycemia.
- Trial name
- NCT00681161
- Testing
- continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Vanderbilt University
Sleep Apnea, Obstructive
Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics
Obstructive sleep apnea (OSA) is a highly prevalent disease resulting from dynamic upper airway collapse during sleep. Continuous positive airway pressure (CPAP) is highly efficacious but high rates of non-adherence to CPAP…
- Trial name
- NCT05429983
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Respiratory Distress Syndrome in Premature Infant
REspiratory MEchanics for Delivering Individualised Exogenous Surfactant
This study is an interventional, non-pharmacological, multicentric, randomized, controlled, superiority, non-profit study. Its primary objective is to evaluate if the administration of surfactant based on FOT assessment will…
- Trial name
- REMEDIES (NCT05791331)
- Testing
- Surfactant administration following lung mechanics assessment in addition to clinical assessment, Surfactant administration following clinical assessment
- Volunteers
- 458 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Obstructive Sleep Apnea
Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea
The purpose of this study is to determine if vitamin D supplement and SGLT-2 inhibitor treatment combination can improve cardiovascular risks in patients with OSA and hypertension, on top of lifestyle modification, before…
- Trial name
- D3DOSA (NCT06690723)
- Testing
- Dapagliflozin (Forxiga), Vitamin D3 ( Colecalciferol), Vitamin D3 plus Dapagliflozin
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- University Malaysia Sarawak
Respiratory Insufficiency, Respiratory Distress Syndrome, Adult
Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet
The aim of this study is to compare two methods of delivery of noninvasive mechanical ventilation (NIV). Since patient compliance and mechanical characteristics of the delivery devices are two fundamental variables in the success…
- Conditions
- Respiratory Insufficiency, Respiratory Distress Syndrome, Adult, Chronic Obstructive Pulmonary Disease, Pulmonary Edema
- Trial name
- NCT00944437
- Testing
- Helmet, Full-face mask
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- University of Parma
Chronic Obstructive Pulmonary Disease
Intrinsic PEEP and Laryngeal Aperture in COPD
In this study the investigators aim to investigate the extent to which in patients with chronic obstructive pulmonary disease narrowing of the vocal cords causes a positive pressure within the airways thus improving airflow and…
- Trial name
- NCT02437630
- Testing
- Oesophageal balloon to measure intra-thoracic pressure, Fibre-optic laryngoscopy, standard lung function tests
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Sleep Apnea Syndromes
The Number and Function of Regular T Cell in Patients With Obstructive Sleep Apnea
To compare the number and function of regular T cell of patients with obstructive sleep apnea (OSA) versus that of age-, gender- and BMI (body mass index)-matched controls
- Trial name
- NCT02342028
- Testing
- OSA
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Respiratory Failure
A Pilot Study of Synchronized and Non-invasive Ventilation ("NeuroPAP") in Preterm Newborns
There is currently a consensus that non-invasive ventilation (NIV) in preterm infants is preferred over intubation. There are two ways of delivering NIV in preterm infants, nasal continuous positive airway pressure (CPAP) or…
- Trial name
- NeuroPAP (NCT02480205)
- Testing
- NeuroBox to deliver the NeuroPAP
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Sleep Apnea, Obstructive, OSA
Telemedicine and Humidification for Cpap IN Osas Key Treatment (THINK Study)
The goal of the study is to test the role of telemedicine combined with humidification to check CPAP treatment during the first month to improve adherence and reduce unsolved side effects of therapy.
- Conditions
- Sleep Apnea, Obstructive, OSA, Sleep, Sleep Disorder
- Trial name
- THINK (NCT04300166)
- Testing
- Telemedicine & Humidification
- Volunteers
- 100 people
- Sponsor
- Andrea Romigi
Obstructive Sleep Apnea
Post Market Clinical Follow up of ResMed Mask Systems
Post Market follow up study to systematically and proactively collect supplementary real world data to confirm the usability and performance of the new generation mask systems. .
- Trial name
- NCT05262439
- Testing
- New generation CPAP mask
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- ResMed
COPD, OSA
Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
To evaluate efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
- Conditions
- COPD, OSA, Lung Function Decreased
- Trial name
- NCT05857475
- Testing
- CPAP therapy, Control
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Obstructive Sleep Apnea
Sleep Schedules Modifications in Sleep Apnea Patients Treated by nCPAP
In Obstructive sleep apnea (OSA) patients, sleep is disrupted and sleep quality is very poor. The investigators can suppose that with continuous positive airway pressure (CPAP) therapy, there is an improvement in sleep quality…
- Trial name
- NCT01355419
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Autonomic Failure, Pure Autonomic Failure
CPAP for the Treatment of Supine Hypertension
This study aims to learn about the effects of continuous positive airway pressure (CPAP) on people with autonomic failure and high blood pressure when lying down (supine hypertension) to determine if it can be used to treat their…
- Conditions
- Autonomic Failure, Pure Autonomic Failure, Multiple System Atrophy, Parkinson Disease
- Trial name
- NCT05489575
- Testing
- Active CPAP, Sleeping in a head-up tilt (HUT) position
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Vanderbilt University Medical Center
Obstructive Sleep Apnea
Right Ventricular Function in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in right ventricular function evaluated by three dimensional echocardiography.
- Trial name
- NCT01201200
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Lung Collapse
Brochoscopic Intervention Versus Conventional Management in Acute Lung Collapse in the Pediatric Intensive Care Unit
This prospective RCT at Cairo University Children Hospitals enrolls critically ill pediatric patients (intubated, NIV, or post-extubation) with lung atelectasis unresponsive to 48 hours of conventional recruitment.
- Trial name
- picu (NCT07383129)
- Testing
- bronchoscope, chest physiotherapy and suction
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
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