Clinical trials: CPAP
Healthy
A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers
Awake prone positioning (APP) has been proven to reduce the intubation rate for patients with COVID-19-induced hypoxemic respiratory failure.
- Trial name
- NCT05512585
- Testing
- awake prone positioning with advanced respiratory support (high-flow nasal cannula or continuous positive airway pressure)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Obstructive Sleep Apnoea (OSA)
Breath Analysis in Obstructive Sleep Apnoea
Clinical trial in patients with obstructive sleep apnoea that are randomised to either continue or withdraw continuous positive airway pressure therapy to identify a disease-specific exhaled breath pattern by mass spectrometry.
- Trial name
- NCT02050425
- Testing
- CPAP
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnea Syndrome
Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use
The primary objective of this randomized clinical trial is to evaluate the role of patient researchers in promoting the resumption of CPAP therapy in apneic patients who had previously stopped CPAP
- Trial name
- NCT04538274
- Testing
- peer-driven intervention
- Volunteers
- 208 people
- Sponsor
- AGIR à Dom
Obstructive Sleep Apnea
Telemedici ne Management of Veterans With Newly Diagnosed Obstructiv e Sleep Apnea (OSA)
Automatically titrating continuous positive airway pressure (APAP) and continuous positive airway pressure (CPAP) are considered first-line treatments for obstructive sleep apnea.
- Trial name
- NCT02159885
- Testing
- Telemonitoring
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
Osa Syndrome
Evaluation of Prophylactic Heated Humidification on Obstructive Sleep Apnea (OSA) Patient Short Term Compliance to CPAP Therapy
To compare two different clinical strategies in order to evaluate the impact of prophylactic heated humidification on OSA patients' compliance to CPAP therapy.
- Trial name
- Humidifier (NCT04391699)
- Testing
- heated humidification
- Where
- France
- Sponsor
- ResMed
Non-Apnoeic Snorers
Snore Positive Airway Pressure Trial
This study will aim to assess the acceptance of the Snore PAP system as a treatment concept for snore. The study will subjectively assess participant and bed partner acceptability and usability of the Snore PAP system and…
- Trial name
- NCT03201055
- Testing
- Snore PAP System
- Where
- New Zealand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ResMed
Sleep Apnea, Pre-diabetes
Mechanisms of Prediabetic States in Sleep Apnea
The purpose of this study is to better understand how sleep apnea contributes to the development of diabetes.
- Trial name
- NCT04234217
- Testing
- Continuous positive airway pressure, Niacin
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Chicago
Respiratory Failure With Hypoxia
Helmet Noninvasive Ventilation vs. High-flow Nasal Cannula in Moderate-to-severe Acute Hypoxemic Respiratory Failure
Helmet noninvasive ventilation and high-flow nasal cannula are novel tools for the first-line treatment of acute hypoxemic respiratory failure.
- Trial name
- HENIVOTpilot (NCT04502576)
- Testing
- Noninvasive respiratory support
- Where
- 5 sites in Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstructive Sleep Apnea of Adult
Acute and Long-term Effects of CPAP in OSA
Two-phase interventional non-inferiority trial (phase 1: at least 8 weeks of CPAP; phase 2: 2 weeks of CPAP withdrawal) including 32 patients with moderate to severe OSA to compare the physiological consequences of a short-term…
- Trial name
- NCT06277115
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Sickle Cell Disease (SCD), Acute Chest Syndrome (ACS)
CPAP for Hypoxemic Acute Chest Syndrome in Sickle Cell Disease
Sickle cell disease (SCD) is a severe hemoglobinopathy, considered the first monogenic disease in the world. Acute chest syndrome (ACS), one of the most frequent and serious complications of SCD, is defined by the association of…
- Trial name
- SIPAP (NCT07703566)
- Testing
- O2+CPAP group
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Apnea, Sleep
Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial
Multiple clinical studies have indicated that obstructive sleep apnea (OSA), the most common chronic sleep disorder, may affect neurocognitive function, and that treatment for continuous positive airway pressure (CPAP) has some…
- Trial name
- NCT02886156
- Testing
- CPAP, BSC
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Obstructive Sleep Apnea
Change in C-reactive Protein (CRP) in Men and Women With Sleep Apnea After Continuous Positive Airway Pressure (CPAP)
C-reactive protein (CRP) is directly implicated in atherogenesis and associated cardiovascular morbidity in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT01365832
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Greece
- Volunteers
- 436 people
- Sponsor
- University of Crete
Asthma, Obstructive Sleep Apnea
Asthma and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common but under-diagnosed form of sleep disordered breathing (SDB). Asthma is a common disease with rising prevalence, which continues to pose significant morbidity and costs.
- Trial name
- NCT01026298
- Testing
- FDA-Approved Treatment
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- University of Wisconsin, Madison
Preterm Infant
Acoustics as a Metric of Airway Pressure in Premature Infants Using Bubble Continuous Positive Airway Pressure
This is an observational, proof-of-concept, feasibility study where 30 preterm infants on bubble CPAP with gestational age < 32+0 weeks will be recruited from the neonatal intensive care unit (NICU) at the Montreal Children's…
- Trial name
- Bubble CPAP (NCT07060833)
- Testing
- External pressure transducer, Standard microphone, Wireless acoustic sensor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Infant, Premature, Diseases, Respiratory Insufficiency Syndrome of Newborn
Impact of CPAP Level on V/Q Mismatch in Premature Infants
Continuous positive airway pressure (CPAP) is used in premature infants to maintain lungs open and facilitate gas exchange. When ventilation/perfusion (V/Q) mismatch is present, areas of the lung that are open for gas exchange do…
- Trial name
- NCT02983825
- Testing
- Continuous positive airway pressure (CPAP); level changes
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
OSA, Apnea+Hypopnea
Effect of Orofacial Myofunctional Therapy on Mouth Air Leak in Patients With Sleep Apnea Treated With CPAP
To verify the effect of orofacial myofunctional therapy in patients with OSA during the use of CPAP with a nasal mask, on the frequency and leak flow.
- Trial name
- NCT05432908
- Testing
- Orofacial exercises and oropharyngeal functions
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Obstructive Sleep Apnea (OSA)
Wearable Device to Promote CPAP Adherence in Obstructive Sleep Apnea (OSA) Patients
The goal of this study type: clinical trial is to evaluate adherence for CPAP used with wearable device in OSA patients comparing with controlled group; could include any of the following: adult patients (≥ 19 yr of age) with…
- Trial name
- NCT07377968
- Testing
- garmin vivoactive 5 with self-monitoring data, Garmin vivoactive 5 without self-monitoring data
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Ramathibodi Hospital
Obese, Sleep Apnea, Obstructive
Nutritional Rehabilitation and Sleep Apnea in the Obese
In obese patients, the prevalence of obstructive sleep apnea (OSA) is around 40% in men and 30% in women. Weight loss after bariatric surgery significantly improves OSA, with 75% of patients having a reduction in OSA severity or…
- Trial name
- DIETSLEEP (NCT03857191)
- Testing
- Nutritional psychocomportemental rehabilitation
- Where
- France
- Volunteers
- 396 people
- Sponsor
- University Hospital, Grenoble
Major Depression, Sleep Architecture
Combining Light Therapy and CPAP in Depression
In a double-blind, parallel-group controlled trial, we aim to measure the effect of two weeks of light therapy combined with the CPAP on compliance CPAP in patients with major depressive disorder.
- Conditions
- Major Depression, Sleep Architecture, Obstructive Sleep Apnea, Compliance
- Trial name
- LUCIOPRESS (NCT06781593)
- Testing
- Light therapy
- Where
- 2 sites in France
- Volunteers
- 130 people
- Sponsor
- Hôpital le Vinatier
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome
The purpose of this study is to determine if Bipap should assume a standard-of-care role in the management of overlap syndrome.
- Conditions
- Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
- Trial name
- OS (NCT01427673)
- Testing
- Bipap procedure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- United States Air Force
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