Clinical trials: CPAP
Obstructive Sleep Apnea Syndrome
The Use of Heliox in Obstructive Sleep Apnea Syndrome
The goals of the project is to evaluate the effects of Heliox therapy on obstructive sleep apnea syndrome (OSAS).
- Trial name
- HOSA (NCT02135900)
- Testing
- Heliox
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwell Health
Ventilation During Resuscitation
Intra Arrest Ventilation in Human Cadavers II
The study investigates the influence of three types of ventilation mode by using Bi-Level positive airway pressure (pinsp 20 mbar, PEEP 5, AF 10/min) with two different types of ventilators ( Medumat vs.
- Trial name
- NCT06885398
- Testing
- treatment
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Muehlenkreiskliniken, MKK
Comorbid Insomnia and Sleep Apnea, Insomnia
Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)
This study investigates the efficacy of a wearable voice-guided Brief Behavioral Therapy for Insomnia (BBTi) combined with a smart eye-mask device for individuals with Comorbid Insomnia and Sleep Apnea (COMISA).
- Conditions
- Comorbid Insomnia and Sleep Apnea, Insomnia, Obstructive Sleep Apnea
- Trial name
- BBTi-COMISA (NCT07521319)
- Testing
- Brief Behavioral Therapy for Insomnia (BBTi), Smart Eye-Mask with Voice-Guided Modules
- Where
- Taiwan
- Volunteers
- 361 people
- Sponsor
- National Sun Yat-sen University
Pulmonary Atelectasis, Respiratory Tract Diseases
Influence of Different Physical Therapy Resources Application After Reduction Stomach Surgery
The aim of this study will be to investigate the effects of using physical therapy resources in the postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01872663
- Testing
- Continuous positive airway pressure, Incentive spirometry, Breath Stacking
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Mild Obstructive Sleep Apnea
Therapy of Oral Appliance for Adults Jordanians With Obstructive Sleep Apnea
Introduction: Obstructive Sleep Apnea (OSA) is the most common form of sleep disordered breathing. Patients who arrive at the dental office with a diagnosis of OSA are often treated with a mandibular advancement device (MAD).
- Trial name
- TOAAJOSA (NCT05087316)
- Testing
- biomimetic oral appliance therapy (BOAT), Standard hospital treatment
- Where
- Jordan
- Volunteers
- 17 people
- Sponsor
- Jordan University of Science and Technology
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
May Noninvasive Mechanical Ventilation (NIV) and/or Continuous Positive Airway Pressure (CPAP) Increase the Bronchoalveolar Lavage (BAL) Salvage in Patients With Pulmonary Diseases?
The objective of our project is to find procedures and/or parameters to predict the diagnostic recovery (≥ 60% of the administered fluid volume) of bronchoalveolar lavage (BAL) fluid before bronchoscopy and to assess the impact…
- Trial name
- PAP+BAL (NCT05631132)
- Testing
- BAL + PAP
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Silesia
Hypertension, Obstructive Sleep Apnea (OSA)
How Wall Squat Exercise Affects Blood Pressure in People With High Blood Pressure and Treated Sleep Apnea (WALLPRESS)
This study will look at whether a simple exercise called the isometric wall squat can help lower blood pressure in adults who have both hypertension and obstructive sleep apnoea treated with CPAP.
- Trial name
- WALLPRESS (NCT07730879)
- Testing
- Isometric Wall Squat
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Aveiro University
Preterm Birth, Respiratory Distress Syndrome
Sustained Lung Inflation and Pulmonary Mechanics in Preterm Infant
Lung protection should start in the delivery room where, from the first breaths, the preterm infant can be helped to clear the lung fluid and to recruit alveolar spaces and establish the functional residual capacity (FRC).
- Conditions
- Preterm Birth, Respiratory Distress Syndrome, Lung Diseases
- Trial name
- NCT02493920
- Testing
- Sustained lung inflation, mask using a T-piece system (Fabian,Acutronic Medical Systems AG, Switzerland).
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Osa Syndrome
Nasal Versus Oronasal Mask in Continuous Positive Airway Pressure (CPAP) Treatment of Patients Affected by Obstructive Sleep Apnea Syndrome (OSAS).
Continuous positive airway pressure (CPAP) is considered the gold standard treatment for patients with moderate to severe obstructive sleep apnea (OSA).
- Trial name
- NCT04681196
- Testing
- patients shifted to nasal mask after persistent OSA with oronasal mask
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Sleep Apnea, Obstructive
Humidity Under Continuous Positive Airway Pressure
Heated humidification in CPAP therapy is often not enough to prevent side effects like dryness of nasal mucosa and xerostomia, especially in cases of mouth breathing or mask leakage.
- Trial name
- NCT01462409
- Testing
- RESMed S9 with humidifier H5i and heated tube Climate Line, CPAP without humidification, CPAP with heated humidification
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Institut für Pneumologie Hagen Ambrock eV
Respiratory Distress Syndrome, Newborn
LISA vs Endotracheal Surfactant in Preterm Neonates: A Lung Ultrasound Distribution Study
This prospective, non-randomized, unblinded pilot study evaluates and compares the intrapulmonary distribution of exogenous surfactant in preterm neonates when administered via Less Invasive Surfactant Administration (LISA)…
- Trial name
- LISA-Ven-LUS (NCT07514481)
- Testing
- surfactant administration by ETT, surfactant administration by thin catheter
- Where
- Qatar
- Volunteers
- 22 people
- Sponsor
- Hamad General Hospital
Epilepsy, Sleep Apnea
Effects of Treating Obstructive Sleep Apnea in Epilepsy
The purpose of this trial is to work out design issues prior to conducting a definitive phase 3 trial to determine whether treating sleep-related breathing disorders in people with epilepsy results in improvement in seizure…
- Conditions
- Epilepsy, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- NCT00047463
- Testing
- continuous positive airway pressure (CPAP)
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Vanderbilt University
Preterm Birth
Delivery Room Practice Change Following the Initiation of the NICHD SUPPORT Trial
This study was designed to analyze whether initiation of the NICHD Neonatal Research Network SUPPORT trial was followed by a change in frequency of endotracheal intubation the delivery room in non-participants and whether these…
- Trial name
- NCT01601886
- Where
- United States
- Volunteers
- 3,843 people
- Sponsor
- Luc Brion
Continuous Positive Airway Pressure [E02.041.625.790.259], Prostatectomy [E04.950.774.860.625]
Continuous Positive Airway Pressure (CPAP) for Preventing Respiratory Failure After Laparoscopic Radical Prostatectomy
Aim of this study is verify if postoperative CPAP after laparoscopic prostatectomy may reduce the impact of postoperative respiratory failure, defined as occurrence of hypoxemia (PaO2<60 mmHg) and/or reduction of Forced…
- Conditions
- Continuous Positive Airway Pressure [E02.041.625.790.259], Prostatectomy [E04.950.774.860.625], Laparoscopy [E01.370.388.250.520], Pneumoperitoneum [C06.844.670]
- Trial name
- NCT01956422
- Testing
- Continuous Positive Airway Pressure(CPAP), Venturi Mask FiO2 40%
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- ASST Fatebenefratelli Sacco
Obstructive Sleep Apnea, Ischaemic Heart Desease
Impact of Continuous Positive Airway Pressure (CPAP) Therapy on Outcomes in Patients Undergoing Coronary Revascularization
Investigators assume that continuous positive airway pressure (CPAP) therapy can reduce the mortality, stroke rate and secondary coronary surgery in CAD with obstructive sleep apnea (OSA) patients after percutaneous coronary…
- Trial name
- NCT02080156
- Testing
- CPAP
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Beijing Anzhen Hospital
Respiratory Distress Syndrome
Non Inferiority Trial Investigating Surfactants Administered Via MIST
RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome.
- Trial name
- Niftisurf (NCT06074380)
- Testing
- MIST surfactant
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Endeavor Health
COVID, Pneumonia, Viral
Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19)
Pneumonia is a recurrent element of COVID-19 infection, it is often associated with development of respiratory failure and patients frequently need various degrees of oxygen therapy up to non invasive ventilation (NIV-CPAP) and…
- Conditions
- COVID, Pneumonia, Viral, Barotrauma, Interstitial Lung Disease
- Trial name
- SequelaeCov (NCT04435327)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Milano Bicocca
Gastric Insufflation, Difficult Mask Ventilation
Comparison of the Effects of Nasal and Oral Airway Use on Gastric Insufflation
The goal of this clinical trial is to compare the effects of nasopharyngeal and oropharyngeal airway on gastric insufflation in patients undergoing general anesthesia and expected difficult mask ventilation.
- Trial name
- NCT05832554
- Testing
- nasal airway, oral airway
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Diskapi Teaching and Research Hospital
Obstructive Sleep Apnea
Usability Evaluation of Menai CPAP Masks
The primary objective of this study is to evaluate the subjective performance of the Menai mask systems (full face, nasal, and pillows variants), compared against Comparison mask systems.
- Trial name
- NCT02364375
- Testing
- Menai mask (full face), Menai Standard mask (full face), Menai mask (nasal)
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- ResMed
Obstructive Sleep Apnoea
Antioxidant Carbocysteine Treatment in Obstructive Sleep Apnoea Syndrome
Obstructive sleep apnoea syndrome (OSAS) is characterised by repeated episodes of upper airway occlusion during sleep.It can cause cycles of hypoxia reoxygenation.
- Trial name
- NCT02015598
- Testing
- Carbocysteine, Continuous Positive Airway Pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
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