Clinical trials: CPAP
Sleep-wake Analysis
Verification of Computerized Sleep-wake Analysis in Sleep Disorders
Objective: Computerized sleep staging has been verified in a normal population. This study attempts to investigate and verify the interpretation of this computerized sleep staging program in patients with sleep disorders, and…
- Trial name
- NCT02412527
- Testing
- Patch III heart rate sensor
- Volunteers
- 330 people
- Sponsor
- Chang Gung Memorial Hospital
Transient Ischemic Attack, Stroke
Sleep Apnea in TIA/Stroke: Reducing Cardiovascular Risk With Positive Airway Pressure
The goal of this study is to develop a novel study design to safely and ethically conduct a long-term randomized controlled trial among patients at high risk for both sleep apnea and cardiovascular events that will examine…
- Trial name
- SleepTight (NCT01446913)
- Testing
- Standard CPAP Intervention, Enhanced CPAP Intervention
- Where
- 2 sites in United States
- Volunteers
- 255 people
- Sponsor
- Yale University
Respiratory Distress Syndrome
Comparing Bubble and Ventilator Nasal CPAP in Preterm Infants
There are various methods to generate the pressure needed for Nasal CPAP. Some neonatal intensive care units (NICU) use an underwater bubbling system and others use a ventilator to generate the pressure.
- Trial name
- NCT02003846
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Maimonides Medical Center
Sleep Apnea, Obstructive
Comparison Study of the ICON™ Auto Series With and Without SensAwake™ and ThermoSmart™ and Conventional Continuous Positive Airway Pressure in Obstructive Sleep Apnea Patients
A total of 216 patients will be randomized into a partially single blind, randomized, parallel-arm trial to determine whether the ICON™ AT with SensAwake™ and ThermoSmart™ can improve therapy adherence when compared to standard…
- Trial name
- NCT01517763
- Testing
- Conventional CPAP Therapy, Fixed pressure ICON™ without ThermoSmart™, Auto ICON™ with SensAwake™ and ThermoSmart™
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Fisher and Paykel Healthcare
Sleep Apnea, Obstructive
Heated Humidified High Flow Nasal Cannula for Children With Obstructive Sleep Apnea
The purpose of this study is to determine whether heated humidified high flow nasal cannula (HHHFNC) is effective as a treatment of obstructive sleep apnea syndrome (OSAS) compared to continues positive airway pressure (CPAP)…
- Trial name
- NCT02515409
- Testing
- HHHFNC, CPAP
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia
Relationship Between EIT and Respiratory Status in Very Preterm Infants
Electrical Impedance Tomography (EIT) is a non-invasive imaging technique that can measure lung function in real time. This study will follow premature infants to see if EIT can help predict which infants will be successful in…
- Conditions
- Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
- Trial name
- NCT06609135
- Testing
- Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lawrence Rhein
Sleep Apnea, Obstructive, Child
Effect of CPAP and Adenotonsillectomy in Upper Airway Volume of Children With OSAS
Obstructive sleep apnea syndrome (OSAS) in children has high prevalence and severe complications, and its first line of treatment (adenotonsillectomy) has risk of complications.
- Conditions
- Sleep Apnea, Obstructive, Child, Continuous Positive Airway Pressure, Adenoidectomy
- Trial name
- NCT03169491
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
COVID-19, COVID-19 Acute Respiratory Distress Syndrome
The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.
Aim: This study was conducted to determine the effect of listening to music during CPAP on the agitation levels of intensive care patients who underwent CPAP due to COVID-19 and their compliance with the treatment.
- Trial name
- NCT05102084
- Testing
- Listening to music with a bluetooth headset to patients receiving CPAP support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- SÜMEYYE BİLGİLİ
Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure
Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria
One in ten babies are born preterm (<37 weeks gestation) globally. Complications of prematurity are the leading cause of death in children under 5 years, with the highest mortality rate in Sub-Saharan Africa (SSA).
- Conditions
- Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure, Prematurity, Oxygen Toxicity
- Trial name
- NCT05508308
- Testing
- OxyMate, Manual oxygen control
- Where
- 2 sites in Nigeria
- Volunteers
- 49 people
- Sponsor
- Murdoch Childrens Research Institute
Bronchiolitis Acute Viral, Bronchiolitis
Nasal Bubble Continuous Positive Airway Pressure in Reducing Respiratory Distress in Children With Bronchiolitis
This study is designed to assess the effectiveness of nasal continuous positive airway pressure in reducing respiratory distress in children with bronchiolitis
- Conditions
- Bronchiolitis Acute Viral, Bronchiolitis, Bronchiolitis Acute, Bronchiolitis, Viral
- Trial name
- NCT04989114
- Testing
- nasal continuous positive airway pressure
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- ameer asadullah gull
Sleep Apnea Syndromes
Sleep Disordered Breathing and Chronic Pain
The purpose of this study is to evaluate positive pressure in patients with chronic pain taking opioid medications who have sleep disordered breathing.
- Trial name
- NCT01457014
- Testing
- servo ventilation auto, Continuous positive airway pressure, servo ventilation manual
- Where
- 4 sites in United States
- Volunteers
- 88 people
- Sponsor
- Philips Respironics
Acute Cardiogenic Pulmonary Edema
Helmet CPAP vs Facemask CPAP in ACPE (hCPAP vs fCPAP)
This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Edema (ACPE) patients in the Emergency Department (ED) delivered by helmet CPAP (hCPAP) and…
- Trial name
- NCT04014088
- Testing
- hCPAP vs fCPAP
- Volunteers
- 164 people
- Sponsor
- Hospital Raja Permaisuri Bainun
Sleep Apnea, Obstructive, Delirium
Effect of CPAP on Postoperative Delirium
Patients with a medical condition known as obstructive sleep apnea may be at increased risk of delirium following surgery. This study loans autotitrating CPAP machines to randomly-selected patients who are at high-risk for…
- Trial name
- NCT01816685
- Testing
- CPAP
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Duke University
Acute Respiratory Failure
Continuous Positive Airway Pressure and Oxygen Concentration on Measurement of Rapid Shallow Breathing Index
To compare the rapid shallow breathing index (RSBI) values, the incidence of adverse reactions, and the predictive accuracy measured under 5 different ventilator strategies in the same patient group.
- Trial name
- NCT00632320
- Where
- Taiwan
- Volunteers
- 98 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
COPD Exacerbation, Oxygen Toxicity
Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
The main objective is to evaluate the FreeO2 device combined with noninvasive respiratory support technique for COPD patients and postoperative bariatric surgery patients.
- Conditions
- COPD Exacerbation, Oxygen Toxicity, Abdominal Obesity, Surgery
- Trial name
- NCT04136717
- Testing
- Washout period, NIV - FreeO2, Nasal High flow Oxygen therapy - FreeO2
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- François Lellouche
COVID-19 Pneumonia
Breathing Effort in Covid-19 Pneumonia: Effects of Positive Pressure, Inspired Oxygen Fraction and Decubitus
The study investigates the role of positive pressure, inspired oxygen fraction and different decubiti (seated, supine, prone) on breathing effort (as assessed by esophageal pressure swings) in Covid-19 pneumonia (at different…
- Trial name
- NCT04885517
- Testing
- Esophageal catheter
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- San Luigi Gonzaga Hospital
Respiratory Distress Syndrome
Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA
This study is to evaluate the safety and tolerability of lucinactant for inhalation, administered as an aerosol in up to four escalating doses to preterm neonates 26 to 28 weeks gestational age who are receiving nCPAP for RDS…
- Trial name
- NCT02528318
- Testing
- Lucinactant for inhalation, nCPAP alone
- Where
- 20 sites in United States, Canada and 2 more
- Volunteers
- 48 people
- Sponsor
- Windtree Therapeutics
Respiratory Distress Syndrome of Newborn
Modified Intubation-surfactant-extubation (InSurE) Technique in Preterm Neonates With Respiratory Distress Syndrome
This study evaluates the less invasive surfactant administration (LISA) combined with synchronized nasal intermittent positive pressure ventilation (SNIPPV) technique in the treatment of respiratory distress syndrome (RDS) of…
- Trial name
- NCT03989960
- Testing
- LISA+SNIPPV, traditional InSurE
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Extreme Prematurity
HFNC and NCPAP in Extremely Preterm Infants
To avoid or decrease the rate of complications in preterm infants after disconnection from a mechanical ventilation (extubation), non-invasive respiratory support is routinely used.
- Trial name
- NCT03649282
- Testing
- HFNC, NCPAP
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Guilherme Sant'Anna, MD
Hypoxia, Endoscopy
Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
This study is a randomized controlled trial comparing oxygen delivery by nasal mask with continuous positive airway pressure versus standard care (nasal cannula or standard facemask) during propofol-based sedation for…
- Conditions
- Hypoxia, Endoscopy, Anesthesia Morbidity
- Trial name
- NCT03369197
- Testing
- Nasal Mask, Control: Nasal Cannula
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
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