Clinical trials: CPAP
Cesarean Section, Infant Conditions
Intact-cord Stabilisation and Physiology-based Cord Clamping in Caesarean Sections
This is a feasibility study with historical control designed to evaluate whether delivery of the placenta prior to umbilical cord clamping at caesarean sections is a feasible, safe and acceptable way of facilitating intact-cord…
- Trial name
- INTACT (NCT05461950)
- Testing
- Extrauterine placental transfusion and physiology-based umbilical cord clamping, Extrauterine placental transfusion, intact cord stabilisation and physiology-based umbilical cord clamping, Delayed umbilical cord clamping
- Where
- Norway
- Volunteers
- 263 people
- Sponsor
- Helse Møre og Romsdal HF
Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS)
The SNORE-trial: Analysis of Alterations in Sleep Stages Following Anesthesia and Their Relation to the Severity of Obstructive Sleep Apnea in the First 3 Nights After Surgery
The goal of this observational study is to learn about the relationship between sleep alterations following anesthesia and their relationship to a potential increase of obstructive sleep apnea (OSA) severity.
- Trial name
- SNORE (NCT06586268)
- Where
- 2 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Medical Device-Related Pressure Injury, Prematurity
Non-Invasive Ventilation Interfaces and Nasal Pressure Injury in Preterm Infants
The goal of this randomized controlled clinical trial is to learn whether different non-invasive ventilation interfaces can prevent medical device-related nasal pressure injury in preterm infants receiving respiratory support in…
- Trial name
- NIV-MDRPI (NCT07521410)
- Testing
- Binasal Prong, Nasal Cannula, Nasal Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Sleep Apnea, Obstructive, Obesity
Life-style Changes in Obstructive Sleep Apnea
The primary aim is to study whether a tailored behavioural medicine intervention addressing physical activity and eating habits have additional effects to continuous positive airways pressure (CPAP) in patients with moderate or…
- Trial name
- NCT01102920
- Testing
- Behavioural strategies to promote physical activity and weight loss, CPAP
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
XOR Levels in OSA Patients (XOR-OSA)
The level of xanthine oxidoreductase (XOR) in plasma is associated with oxidative stress and inflammation. Obstructive Sleep Apnea (OSA) is characterized by repeated upper airway obstruction and apneas during sleep, leading to…
- Trial name
- XOR-OSA (NCT06554496)
- Testing
- CPAP Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing Medical University
Heart Failure, Obstructive Sleep Apnea
ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea.
Obstructive sleep apnea (OSA), central sleep apnea (CSA) and heart failure (HF) are states of metabolic demand and sympathetic nervous system (SNS) activation.
- Conditions
- Heart Failure, Obstructive Sleep Apnea, Central Sleep Apnea
- Trial name
- AMEND (NCT02116140)
- Testing
- [C11]Acetate and HED PET
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Respiratory Distress Syndrome, Newborn
The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility Study
The purpose of this study is to evaluate the safety and utility of using heliox gas in combination with nasal CPAP in premature infants.
- Trial name
- NCT00739115
- Testing
- Heliox gas
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Hawaii Pacific Health
Mechanical Ventilation Complication
Heartrate Variability During Conventional and Variable Pressure Support Mechanical Ventilation
Rationale Studies show that about a third of all postoperative complications are due to cardiovascular reasons. Furthermore it was shown that more than 50% of postoperative deaths are associated with severe cardiovascular…
- Trial name
- NCT03360968
- Testing
- Variable-PS, SPN-CPAP/PS
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Transient Ischemic Attack, Sleep Apnea
Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack
Generalist physicians in the outpatient setting care for 80% of the 300,000 patients who have transient ischemic attacks (TIA) annually in the United States.
- Trial name
- NCT00251290
- Testing
- auto-titrating continuous positive airway pressure
- Where
- 3 sites in United States
- Volunteers
- 62 people
- Sponsor
- Yale University
Dilated Cardiomyopathy
BiPAP for Cardiomyopathy With Central Sleep Apnea
We investigated whether treatment of central sleep apnea-hypopnea with bilevel positive airway pressure (BiPAP) in patients with idiopathic dilated cardiomyopathy (IDCM) would improve LV function.
- Trial name
- NCT00282789
- Testing
- bilevel positive airway pressure, bilevel positive airway pressure (Device)
- Where
- Japan
- Sponsor
- Nagoya University
Obstructive Sleep Apnea
Measurement of Critical Closing Pressure (Pcrit) During Drug-Induced Sleep Endoscopy (DISE)
This study intends to test the feasibility of measurement of the critical closing pressure (Pcrit) during drug-induced sleep endoscopy (DISE) for use in future studies, which are aimed at finding an alternative method for patient…
- Trial name
- Pcrit-DISE (NCT04232410)
- Testing
- Drug induced sleep endoscopy, Measurement of critical closing pressure of the uppper airway
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- University Hospital, Antwerp
Chronic Respiratory Failure, Nasal High Flow Therapy
The Efficacy of Nasal High Flow Oxygen Therapy With Rehabilitation in the Patients With Chronic Respiratory Failure
The purpose of this study is to compare the exercise endurance between oxygen therapy with rehabilitation and nasal high flow therapy with rehabilitation for the patients with chronic respiratory failure receiving long-term…
- Conditions
- Chronic Respiratory Failure, Nasal High Flow Therapy, Rehabilitation, Exercise Endurance
- Trial name
- NCT02804243
- Testing
- nasal high flow therapy
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Acute Respiratory Failure With Hypoxia
Positive Pressure During Bronchoscopy
It has been demonstrated the application of noninvasive positive pressure ventilation (NPPV) to assist spontaneous breathing through a face mask during fiberoptic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) in severely…
- Trial name
- NCT02167542
- Testing
- Noninvasive Positive Pressure Ventilation, CPAP valve (Boussignac)
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Hospital Sao Joao
Obstructive Sleep Apnea
Effects of PAP Treatment of OSA in Patients With Heart Failure
The purpose of this study is to see if treatment of OSA with the CPAP device makes a difference to insulin resistance and heart disease.
- Trial name
- OSA-MRI (NCT01136122)
- Testing
- CPAP Treatment
- Where
- United States
- Sponsor
- Ulysses Magalang MD
Obstructive Sleep Apnea of Adult
Acceptable Pressure Range for Continuous Positive Airway Pressure(CPAP) Treatment
Compliance of continuous positive airway pressure （CPAP） derived from auto-titration is similar to that derived from manual titration, although pressure derived from the former was usually 2-5 cmH2O higher than the latter.
- Trial name
- NCT04925466
- Testing
- CPAP at pressure of 10 cmH2O, CPAP at minimal effective pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- State Key Laboratory of Respiratory Disease
Pneumonia
Bubble Continuous Positive Airway Pressure for Children With Severe Pneumonia in Mali, Africa
This study is being conducted in Mali, Africa. Pneumonia is a respiratory infection of the lungs caused by bacteria or virus. Some children can develop signs of severe pneumonia and as a result, have difficulty breathing and low…
- Trial name
- NCT03944551
- Testing
- Bubble CPAP, Standard Therapy
- Where
- Mali
- Volunteers
- 13 people
- Sponsor
- University of Maryland, Baltimore
Cancer
CPAP for Motion Management in Breast Radiotherapy; and Lung & Liver SABR
A phase II trial to determine the proportion of patients where the use of continuous positive airway pressure (CPAP) results in a superior radiation plan compared to standard planning procedures.
- Trial name
- CPAP-RT (NCT05396950)
- Testing
- CPAP
- Volunteers
- 70 people
- Sponsor
- Waikato Hospital
Treatment of Excessive Daytime Sleepiness in Narcolepsy
Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.
3. RATIONALE FOR BF2.649 IN NARCOLEPSY Narcolepsy is a disabling syndrome affecting the generation and organizations of sleep and wakefulness, first described by Westphal and Gelineau in 19th century.
- Trial name
- NCT01638403
- Testing
- BF2.649, Vigil, palcebo
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Bioprojet
Obstructive Sleep Apnea
PAP-NAP Device Clinical Study
This exploratory pilot study will evaluate the usability and short-term tolerability of a novel positive airway pressure (PAP) device in adults during a supervised daytime nap session in a simulated sleep environment.
- Trial name
- NCT07785310
- Testing
- APL Device
- Volunteers
- 10 people
- Sponsor
- ResMed
Ischemic Stroke, Intra Cerebral Hemorrhage
Stroke and CPAP Outcome Study 3
A problem with breathing during sleep, called obstructive sleep apnea (OSA), likely increases the risk of stroke and is common in people who have had a stroke, present in about 2/3 of stroke survivors.
- Conditions
- Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment
- Trial name
- SCOUTS3 (NCT06029959)
- Testing
- Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
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