Clinical trials: Caffeine, completed
Stroke
Drug-Drug Interaction Study of MLC1501 Using Cocktail of Drugs Acting as Sensitive Clinical Probes/Substrates of Cytochrome P450 Isoenzymes and Transporters in Healthy Subjects
This is a single-centre phase I study to assess the Drug-Drug Interaction potential of MLC1501 with a cocktail of drugs acting as sensitive clinical probe substrates of Cytochrome P450 isoenzymes and Transporters in healthy…
- Trial name
- NCT04233437
- Testing
- MLC1501, CYP Cocktail, Transporter Cocktail
- Where
- Australia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Moleac Pte Ltd.
Sleep Disorders, Obese Pregnant Women
A Nurse-Led Sleep Hygiene and Progressive Muscle Relaxation Intervention on Sleep Quality Among Obese Pregnant Women
Sleep is essential for maternal and fetal health, with adequate sleep being crucial for energy, fetal development, and overall pregnancy well-being.
- Trial name
- NCT06890910
- Testing
- evidence based intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Hypertension, Healthy
Effect of Oral Caffeine and L-Citrulline Supplementation on Arterial Function in Healthy Males
Caffeine is an exceedingly popular and consumed pharmacological agent. Although caffeine is primarily consumed from coffee and tea beverages, it is also available in other forms such as sodas, energy drinks, tablets and capsules.
- Trial name
- NCT02214290
- Testing
- Caffeine, L-citrulline
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Florida State University
Caffeine
5 vs 10-Minute Chewing of Caffeinated Gum: Plasma Caffeine Pharmacokinetics
The goal of this study is to understand how chewing duration affects how quickly caffeine from caffeinated chewing gum appears in the blood and how long higher caffeine levels are maintained.
- Trial name
- NCT07386899
- Testing
- Caffeine 300 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Periorbital Area
A Clinical Trial to Evaluate the Effects of an Eye Serum on Improving the Appearance of the Periorbital Area
This study will evaluate the efficacy of the DIME Beauty Luminosity Eye Serum in improving the appearance of skin in the periorbital eye area. This study will last for 60 days.
- Trial name
- NCT06143033
- Testing
- DIME Beauty Luminosity Eye Serum
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dime Beauty Co.
Parkinson's Disease
Caffeine for Motor Manifestations of Parkinson's Disease
Numerous epidemiological studies have linked lifelong use of caffeine to a lower risk of Parkinson's disease (PD) - prospective studies have estimated that non-coffee drinkers have an approximately 1.7-2.5 fold increased risk of…
- Trial name
- NCT01190735
- Testing
- Caffeine alkaloid
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Ron Postuma
Exercise Performance, Metabolism
Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance
The purpose of this randomized, double-blind, crossover study is to investigate the effects of Bang® Keto Coffee on resting and post-exercise metabolism and muscular performance during lower body resistance exercise.
- Trial name
- NCT04180787
- Testing
- Beverage Consumption
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Hypercapnia
Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded Hypercapnia
The aim of this randomized, double-blind, placebo-controlled crossover trial is to determine the effects of caffeine vs. placebo on psychomotor vigilance and carbon dioxide tolerance during graded hypercapnia.
- Trial name
- C3F (NCT06636825)
- Testing
- Graded hypercapnia, Caffeine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
cMET-dysregulated Advanced Solid Tumors
A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors
Drg-drug Interaction (DDI) study to assess the effect of INC280 on the pharmacokinetics of midazolam and caffeine in patients with cMET-dysregulated advanced solid tumors
- Trial name
- NCT02520752
- Testing
- INC280, Midazolam, Caffeine
- Where
- 12 sites in United States, Bulgaria and 5 more
- Volunteers
- 37 people
- Sponsor
- Novartis Pharmaceuticals
Medication Adherence, Kidney Transplantation
Teen Adherence in KidnEy Transplant Improving Tracking To Optimize Outcomes - Stage 3
Medication non-adherence is a major problem in kidney transplant recipients; young people 12-24 years of age are at particularly high risk for non-adherence and graft failure compared to young children and adults.
- Trial name
- NCT04288271
- Testing
- Adherence Intervention, Healthy living education intervention
- Where
- 8 sites in United States, Canada
- Volunteers
- 96 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Stroke
Evaluation of the ReVive SE Device for Intra-Arterial Thrombectomy in Acute Ischemic Stroke
The main objective of this study is to assess the safety and effectiveness of the ReVive SE (Self- Expanding) Neurothrombectomy Device in subjects requiring mechanical thrombectomy when used according to its Instruction for use…
- Trial name
- Re-ACT (NCT02169492)
- Where
- 8 sites in France
- Volunteers
- 103 people
- Sponsor
- Codman & Shurtleff
Obesity
B181 Metobes-III: Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)
To investigate the 5-hour acute effect on energy expenditure, substrate oxidation and ad libitum food intake after intake of the Metobes-compound (green tea extract, capsaicin, tyrosine, caffeine).
- Trial name
- NCT00302263
- Testing
- Metobes-compound
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Caffeine, Biomechanics
Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic…
- Conditions
- Caffeine, Biomechanics, Fatigue, Injuries
- Trial name
- NCT06039358
- Testing
- Caffeine., Cellulose.
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Molecular Imaging
Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue
The primary objective of this study is to determine if exercise, fasting, or eating prior to the molecular breast imaging study will have an effect on the uptake of the tracer in the breast tissue.
- Trial name
- NCT01944215
- Testing
- Meal, Exercise, Sestamibi
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non Small-cell Lung Cancer, Renal-cell Cancer
Cytochrom p450 3A4 and 1A2 Phenotyping for the Individualization of Treatment With Sunitinib or Erlotinib in Cancer Patients
It is well known that substantial interindividual variability of CYP3A4/1A2-phenotype activity is an important contributor to individual differences in the sensitivity to the frequently used tyrosine kinase inhibitors sunitinib…
- Conditions
- Non Small-cell Lung Cancer, Renal-cell Cancer, Gastrointestinal Stroma Tumor
- Trial name
- NCT01402089
- Testing
- Sunitinib, Erlotinib, Midazolam
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- Markus Joerger
Obesity
A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants
The main purpose of this study is to determine the effect of LY3437943 when administered subcutaneously on the levels of midazolam, warfarin and caffeine in the blood stream when administered orally as a drug cocktail in obese…
- Trial name
- NCT05445232
- Testing
- LY3437943, Midazolam, Warfarin
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Eli Lilly and Company
Intraocular Pressure
Modifiable Factors and Glaucoma - RCT
There is growing awareness that environmental factors, behaviors and diet are intimately related to patient health and may play a role in the pathogenesis and progression of glaucoma.
- Trial name
- NCT02972749
- Testing
- Intervention
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Wolfson Medical Center
Anesthesia
MAPD: Modifiable Factors Affecting Propofol Dosing
The investigators aim to understand the effect of a caffeine intake, sleep habits, anxiety about surgery, alcohol intake and smoking status upon the dose of the anaesthetic drug, propofol, required for anaesthetic induction.
- Trial name
- NCT03453099
- Testing
- Preoperative Questionnaires, Postoperative Subjective Pain Scores
- Where
- United Kingdom
- Volunteers
- 91 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Urinary Bladder, Overactive, Sexual Behavior
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron in Sexually Active Men With OAB Symptoms
The objective of this study is to evaluate and compare the therapeutic effects on OAB symptoms, and sexual functions, in terms of erectile function and ejaculatory function, in sexually active OAB male treated with behavior…
- Conditions
- Urinary Bladder, Overactive, Sexual Behavior, Sexual Activity, Behavior Therapy
- Trial name
- NCT04420533
- Testing
- Behavior therapy alone, Mirabegron 50 MG Extended Release Oral Tablet
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Physical Performance, Cognitive Performance
Effects of Supplementation on Performance in Football Players
This study investigated the effects of short-term supplementation with taurine, caffeine, and phosphatidylserine on physical and cognitive performance in professional male football players.
- Trial name
- FOOTBALL-TCP (NCT07580248)
- Testing
- Taurine and Caffeine, Taurine, Caffeine, and Phosphatidylserine
- Where
- Poland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Krzysztof Mizera