Clinical trials: Caffeine
Type 1 Diabetes
Safety of Overestimation of a Meal Insulin Bolus in the Context of Dual-hormone Closed-loop Operation - Part 2
In previous studies, investigators have studied if a pre-meal insulin bolus based on estimated carbohydrate meal size would alleviate the burden of carbohydrate counting without a significant degradation in postprandial glucose…
- Trial name
- NCT02798250
- Testing
- Dual-hormone closed-loop, Insulin, Glucagon
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Blood Flow in Healthy Volunteers
Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia
The endogenous nucleoside adenosine can induce various cardiovascular and neurohumoral effects by stimulation of specific adenosine receptors.
- Trial name
- NCT00253929
- Testing
- Intra-arterial infusion of adenosine, intra-arterial infusion of caffeine, intra-arterial infusion of acetylcholine
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Caffeine, Exercise
7-Day Caffeine and Upper-Body Power in Active Women
This study investigated the effects of a 7-day caffeine supplementation on heart rate variability, cognitive performance, and upper-body anaerobic power in active women.
- Conditions
- Caffeine, Exercise, Physical Fitness
- Trial name
- NCT07771556
- Testing
- Caffeine
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Birjand University of Medical Sciences
Respiratory Distress Syndrome in Premature Infant, RDS of Prematurity
Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa
The goal of this pragmatic clinical trial is to learn if the drug surfactant given by a less invasive technique works to treat respiratory distress in preterm infants in low- and middle-income African countries where invasive…
- Conditions
- Respiratory Distress Syndrome in Premature Infant, RDS of Prematurity, Surfactant Deficiency Syndrome Neonatal, Premature Birth
- Trial name
- NCT06554522
- Testing
- Surfactant
- Where
- 8 sites in Central African Republic, Ghana and 2 more
- Volunteers
- 1,512 people
- Sponsor
- Indiana University
Coronary Artery Disease
Effects of Espresso on Platelet Aggregability in Patients with Coronary Artery Disease
Discovered thousands of years ago, coffee is among the most consumed beverages in the world. The relationship between coffee and cardiovascular risk, more specifically coronary artery disease, is controversial.
- Trial name
- NCT04827251
- Testing
- Coffee
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- University of Sao Paulo
Physical Performance, Placebo Effect
Placebo Effect on Cycling Performance: Laboratory Crossover Study
This study aims to determine the impact of the placebo (PLA) effect on physical and cognitive performance in a controlled laboratory setting.
- Conditions
- Physical Performance, Placebo Effect, Cognitive Performance
- Trial name
- NCT07748429
- Testing
- Caffeine (6mg/kg)
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Infertility, Female, IVF
Fertility Supportive Behavior Education Based On Watson's Theory Of Human Care
Infertile individuals frequently attempt behavioral changes to enhance the effectiveness of their treatment and improve fertility outcomes.
- Trial name
- NCT06591637
- Testing
- Fertility supportive behavior education based on Watson's Theory of Human Care, Routine nursing care, The booklet "Fertility-Supporting Health Training
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cardiovascular Disease, Ischemia-Reperfusion Injury
Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury?
The purpose of this project is to explore the interaction between caffeine and dipyridamole on ischemia-reperfusion injury in the forearm.
- Trial name
- NCT00430170
- Testing
- Dipyridamole, caffeine
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Smoking
Effects of Smoking Environment on Craving and Smoking
The goal of this study is to evaluate the effects of exposure to standard smoking environments on ability to resist smoking as measured with a Delay to Smoking Task.
- Trial name
- CC2pilot (NCT02416986)
- Testing
- 6 hour smoking abstinence, Delay to Smoking Task (smoking cues), Delay to Smoking Task (nonsmoking cues)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Duke University
Alzheimer Disease, Dementia Alzheimers
An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions
The goal of this study will be to design, implement and test the impact of a quality improvement (QI) intervention that uses an EHR CDS tool among physicians newly ordering an antipsychotic medication for older adults with ADRD.
- Conditions
- Alzheimer Disease, Dementia Alzheimers, Dementia of Alzheimer Type
- Trial name
- NCT04851691
- Testing
- EHR CDS, Usual Care
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of California, Los Angeles
Epilepsy
Generalized Seizure Detection And Alerting In The EMU With The Empatica Embrace Watch And Smartphone-Based Alert System
To demonstrate safety and effectiveness of the Embrace device in identifying convulsive seizures (CS) and notifying a caregiver during patient hospitalization at an epilepsy monitoring unit (EMU).
- Trial name
- NCT03207685
- Testing
- Additional Seizure Monitoring
- Where
- 2 sites in United States, Italy
- Volunteers
- 100 people
- Sponsor
- Empatica, Inc.
Insomnia
Effectiveness of a Guided Self-help Intervention for Improving Sleep in University Students
This randomized controlled trials aims to assess the effectiveness of an online guided self-help intervention ('i-Sleep \& BioClock') based on CBTi principles for university students' sleep problems.
- Trial name
- NCT06023693
- Testing
- i-Sleep & BioClock, Online Psychoeducation
- Where
- Netherlands
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Obesity
Long-term Effects of Green Tea on Gut Flora, Fat Absorption, Body Composition and Resting Energy Expenditure
Green tea may have positive effects for weight control and on body composition via several approaches such as a positive effect on the gut flora, a decrease in fat absorption from the intestines and an increase in resting energy…
- Trial name
- NCT01556321
- Testing
- green tea (757 mg/capsule [84.5 mg EGCG + 2.1 mg caffeine ]
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Amyotrophic Lateral Sclerosis
A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis
This first-in-human, double-blind, placebo-controlled Phase I study will be conducted in participants with amyotrophic lateral sclerosis (ALS) to explore safety, tolerability, and pharmacokinetic (PK) properties of GDC-0134.
- Trial name
- NCT02655614
- Testing
- GDC-0134, Rabeprazole, Midazolam
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 54 people
- Sponsor
- Genentech, Inc.
Neural Tube Defects
Influence of "Espresso" on Adsorption of Myo-inositol
Neural Tube Defects (NTDs) are multifactorial (genetic/environmental) diseases that arise from failure of embryonic neural tube closure.
- Trial name
- NCT01244399
- Testing
- Inositol
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Diabetes Mellitus, Depression
Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression
This clinical trial will compare the effectiveness of the Healthy Outcomes through Patient Empowerment (HOPE) intervention to enhanced usual care (EUC) for diabetes and depression at 6 and 12 month follow-up.
- Trial name
- NCT01572389
- Testing
- Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Coronary Artery Disease (CAD)
Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)
Observe whether the administration of caffeine prior to regadenoson will affect the interpretation of test results in subjects with coronary artery disease (CAD) undergoing SPECT MPI
- Trial name
- NCT00826280
- Testing
- regadenoson, overencapsulated caffeine, technetium
- Where
- 25 sites in United States
- Volunteers
- 347 people
- Sponsor
- Astellas Pharma Inc
Caffeine, Placebo
Caffeinated Chewing Gum on 400-meter Performance
20 trained sprinter were divided into caffeine Gum trial (CAF) and Placebo trial (PL) with a randomized, double-blind study design.
- Trial name
- NCT06430996
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Fractures, Bone, Cardiovascular Abnormalities
Using a Remote Patient Monitoring Alert System to Improve Care
The purpose of this study is to determine the efficacy of a remote patient monitoring platform and alert system in reducing adverse events for hospitalized geriatric orthopedic trauma patients.
- Conditions
- Fractures, Bone, Cardiovascular Abnormalities, Respiratory System Abnormalities, Hemorrhage
- Trial name
- NCT02933840
- Testing
- AlertWatch
- Sponsor
- Massachusetts General Hospital
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in…
- Trial name
- ADPKD (NCT06786260)
- Testing
- Interventional Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Loma Linda University
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