Clinical trials: Caffeine
Obesity
Thermogenenic Responses to Fasting and Overfeeding in Women
This study plans to learn more about why menopause increases the risk of weight gain. During and after menopause, women are prone to increased weight gain.
- Trial name
- NCT06610162
- Testing
- Eucalaloric feeding, Acute Fasting, Acute Overfeeding
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction
Randomized Evaluation for Failed TAVR
REVIVE TAVR is an acronym for the Randomized Evaluation of Valve-In-Valve versus Explantation for failed TAVR. This is a prospective, multicenter, global randomized trial investigating the safety and efficacy of reintervention…
- Conditions
- Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction, Prosthesis Failure
- Trial name
- REVIVE-TAVR (NCT06400342)
- Testing
- TAVR-explant, Redo-TAVR
- Volunteers
- 264 people
- Sponsor
- Medstar Health Research Institute
Gastroesophageal Reflux Disease
Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: Can stellate ganglion block improve gastroesophageal reflux…
- Trial name
- NCT06215742
- Testing
- Rehabilitation therapy, Stellate ganglion block
- Where
- China
- Sponsor
- Zeng Changhao
Neurologic Symptoms
Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study
Fasciculations are clinically defined as spontaneous intermittent contractions of a portion of muscles. Depending on associated symptoms they may be a sign of lower motor neuron disorder.
- Trial name
- NCT05977920
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zurich Regional Health Center
Dietary Modification
Effects of a Pre-Workout Dietary Supplement on Training Adaptations
The purpose of this study is to examine the effects of a pre-workout dietary supplement during resistance training on training adaptations.
- Trial name
- NB2 (NCT02999581)
- Testing
- C4 Extreme, C4 Extreme (without Advantra Z)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Healthy
The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)
To assess the influence of BI 187004 on kinetics of cytochrome P450 (CYP) and P glycoprotein (P-gp) probe drugs as a means of predicting drug-drug interactions.
- Trial name
- NCT02254148
- Testing
- midazolam, caffeine, digoxin
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pain
Exploratory Study to Investigate Cognition Function and Mobility in Individuals With Pain
This parallel, assessor blind, placebo-controlled, stratified, randomized study will investigate the effects of everyday pain on cognition and mobility in otherwise healthy individuals.
- Trial name
- NCT02974114
- Testing
- Paracetamol and caffeine, Paracetamol
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Schizophrenia, Caffeine
The Impact of Caffeine on Cognition in Schizophrenia
Caffeine is the most used psychoactive drug in Canada, with regular consumption by 88% of the adult population, While rates of caffeine consumption are considered to be high in the general population, there is some evidence that…
- Trial name
- NCT02832401
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Diabetes, Diabetes Complications
Pressure-Sensing Insoles in the Neuropathic Ulcer Treatment Pathway
Diabetic foot ulceration (DFU) is a common complication with a 25% lifetime risk in patients with diabetes. While most of these ulcers can be treated successfully on an outpatient basis, some will persist and become infected.
- Conditions
- Diabetes, Diabetes Complications, Neuropathy, Peripheral Neuropathy
- Trial name
- PINUP (NCT02586519)
- Testing
- SurroSense Rx System
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary
Overweight
Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance
Habitual consumption of coffee may have substantial beneficial effects on glucose metabolism according to recent findings of epidemiological studies in the U.S., Europe, and Japan.
- Trial name
- NCT00305097
- Testing
- Decaffeinated coffee, Caffeinated coffee, No coffee
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Healthy Volunteers
A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants
This study is designed to assess the effect of BMS-986196 on the drug levels of caffeine, montelukast, flurbiprofen, omeprazole, midazolam, digoxin, and pravastatin in healthy participants.
- Trial name
- NCT05852769
- Testing
- BMS-986196, Caffeine, Montelukast
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Dengue
Combating Dengue With Innovative, Paradigm-shift-Strategies: Early Dengue Surveillance in Adult Aedes Mosquitoes
During dengue outbreaks, the Ministry of Health Malaysia employs various methods to control the spread of disease, including killing the larvae of Aedes mosquitoes, fogging, together with educating and disseminating information…
- Trial name
- NCT03799237
- Testing
- GOS trap and dengue NS1 antigen kit
- Where
- Malaysia
- Volunteers
- 7,979 people, healthy volunteers welcome
- Sponsor
- Jonathan Liew Wee Kent
Postoperative Care, Postoperative Complications
Nutrition to Support Postoperative Recovery
Older surgical patients commonly have malnutrition, and there is evidence these patients have increased risk for poor physical and brain recovery after surgery and anesthesia.
- Conditions
- Postoperative Care, Postoperative Complications, Cognition, Nutritional Assessment
- Trial name
- NCT07109505
- Testing
- Nutritional Shake, Nutritional Instructions Only
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Dysmenorrhea, Spinal Stabilization
The Effect of Spinal Stabilization Training in Women With Dysmenorrhea
The study, designed as a randomized controlled experimental trial, was conducted at Tonya Vocational School. Institutional approval was obtained to carry out the study at Tonya Vocational School (Appendix-).
- Conditions
- Dysmenorrhea, Spinal Stabilization, Menstrual Symptoms, Exercise Training
- Trial name
- NCT07563426
- Testing
- Spinal stabilization exercise group, Relaxation exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sevtap Günay
Cold
Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold
The primary objective of this study is to evaluate the non-inferiority of Coristina® d in the symptomatic treatment of the common cold compared to Resfenol® comparator.
- Trial name
- NCT02735070
- Testing
- Resfenol, Coristina d
- Volunteers
- 366 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Postoperative Ileus
Coffee Consumption for Intestinal Function Recovery After Laparoscopic Gynecologic Surgery
Minimally invasive surgery (MIS) has revolutionized women's healthcare. Laparoscopy is an excellent route of MIS. Today, laparoscopic surgery is one of the major procedure in the management of a gynecologic disease.
- Trial name
- NCT03963180
- Testing
- coffee
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
HIV Disease Progression
Reducing Mortality in Adults With Advanced HIV Disease (REVIVE)
A double blinded, placebo-controlled, multicenter trial to evaluate effectiveness of azithromycin prophylaxis on mortality in advanced HIV.
- Trial name
- REVIVE (NCT05580666)
- Testing
- Azithromycin Oral Tablet
- Where
- 52 sites in Côte d’Ivoire, Ethiopia and 9 more
- Volunteers
- 8,000 people
- Sponsor
- Population Health Research Institute
Premenstrual Syndrome, Pilates Exercise
Clinical Pilates' Impact on Fitness, Symptoms & Kinesiophobia in PMS
Premenstrual syndrome (PMS) is characterized by a series of somatic and psychological symptoms of varying severity that occur during the luteal phase of the menstrual cycle, affecting approximately 30% of women and resolving with…
- Trial name
- NCT06835062
- Testing
- Recommendations for Enhancing General Well-Being, Clinical Pilates
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Major Depressive Disorder, Suicidal Ideation
MicroRNA Correlates of Childhood Maltreatment and Suicidality
This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g.
- Trial name
- NCT04923685
- Testing
- Trier Social Stress Test
- Where
- 2 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
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