Clinical trials: Caffeine
Injury of Foot, Shoulder or Knee, Perineural Analgesia
Postoperative Patient-controlled Perineural Analgesia After Orthopedic Surgery by "Remote Control" Versus "Bedside Care"
Perineural injection of local anesthesic is currently the reference method for the treatment of post operative pain in a patient undergoing major orthopedic surgery. Postoperative pain is a dynamic phenomena in every patient.
- Conditions
- Injury of Foot, Shoulder or Knee, Perineural Analgesia, Pain, Postoperative
- Trial name
- MICREL (NCT02018068)
- Testing
- Remote control, At bedside care
- Where
- 4 sites in France, Netherlands and 1 more
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Drug Interaction
Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport
This is a single center, open-label, fixed sequence Phase 1, drug-drug interaction (DDI) study in healthy subjects.
- Trial name
- NCT05334108
- Testing
- Ecopipam, Cohort 1 Probe Substrate Cocktail, Cohort 2 Probe Substrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Emalex Biosciences Inc.
Pediatric Obesity
Body Composition Changes With Albuterol and Caffeine Versus Placebo in Adolescents
The purpose of this study is to determine whether taking a combination of caffeine and albuterol three times per day will increase muscle and decrease fat in your child's body and to determine how these medications make your…
- Trial name
- CAMP (NCT02740660)
- Testing
- Caffeine 100mg / Albuterol 4mg, Family weight management counseling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Dancesport Performance
Effects of Combined Rhodiola Rosea and Caffeine Supplementation on Dancesport Performance
This study evaluates the effects of caffeine, Rhodiola rosea, and their combined supplementation on dancesport-specific performance in male collegiate dancesport athletes.
- Trial name
- RHO-CAF-DanceS (NCT07690085)
- Testing
- Caffeine, Rhodiola Rosea Capsules, Standardized cowboy-dance-specific training program
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Coronary Disease
The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease
Prior work (Chris, M. et al, Clinical Science 2005; 109, 55-60) has demonstrated that drinking a cup of coffee (80-100 mg of caffeine) an hour before endothelium-dependent FMD (flow-mediated dilatation) of the brachial artery…
- Trial name
- NCT00564824
- Testing
- Caffeine
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Adult Population
The Acute Effects of Caffeine on Exercise and Cognition
The effects of moderate intensity aerobic exercise and caffeine ingestion on cognition (more specifically working memory) in non-caffeine drinker and caffeine drinkers will be examined.
- Trial name
- AEC (NCT03400423)
- Testing
- Caffeine, Moderate Intensity Exercise
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Hyperthermia
Military Alerting System for Monitoring Body Temperature During Active Cooling
BHSAI is developing a computational system that provides early alerts of a rise in core body temperature to help reduce the risk of heat injury in the field and during training.
- Trial name
- MAMBA (NCT04431596)
- Testing
- Forearm cooling, Mist-fan cooling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Post-Dural Puncture Headache
Pregabalin Versus Hydrocortisone for Postdural Puncture Headache After Spinal for Cesarean
Postdural puncture headache (PDPH) is a common complication after spinal anesthesia. The role of pregabalin and hydrocortisone in the treatment of PDPH is unclear.
- Trial name
- PDPH (NCT03910088)
- Testing
- Pregabalin 100Mg Oral Cap, Hydrocortisone, Acetaminophen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Healthy, Alcohol Drinking
Binge Drinking of Alcohol Mixed With Energy Drinks
The purpose of the study is to assess the relevance of gender in the acute effects (subjective, physiological and driving-related skills) observed after controlled administration of alcohol in a binge-drinking pattern mixed with…
- Trial name
- ENERGYBINGE (NCT04616859)
- Testing
- Alcohol and Energy Drink (AmED)
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Caffeine
Caffeinated Gum Softball Performance
The purpose of this study was to investigate the effects of caffeinated chewing gum on female softball pitching and hitting performance.
- Trial name
- NCT06079996
- Testing
- CAFFEINE GUM
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Cognitive Performance
Assessing the Effectiveness of an N-of-1 Platform Using Study of Cognitive Enhancers
The growing consumer-grade molecular and digital wellness market is generating unprecedented volumes of information to support decision-making around individual health.
- Trial name
- NCT04056650
- Testing
- L-theanine, Caffeine supplement, N1 app
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Relapsing-Remitting Multiple Sclerosis
An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis
The primary objective of the study is to assess the immunogenicity of Daclizumab High Yield Process (DAC HYP) 150 mg administered every 4 weeks by subcutaneous (SC) injection using the pre-filled syringe (PFS) in participants…
- Trial name
- OBSERVE (NCT01462318)
- Testing
- Midazolam, Caffeine, S-warfarin
- Where
- 19 sites in United States, Czechia and 2 more
- Volunteers
- 133 people
- Sponsor
- Biogen
Beetroot Juice, Caffeine
Acute Effects of Beetroot Juice and Caffeine Co-ingestion on Lower-limb Strength and Muscular Endurance in Females
The aim of this study is to evaluate the acute effects of beetroot juice and caffeine, consumed individually or in combination, on lower-limb strength and muscular endurance in physically active women.
- Conditions
- Beetroot Juice, Caffeine, Placebo, Beetroot Juice with Caffeine Co-ingestion
- Trial name
- NCT06758323
- Testing
- Beetroot juice combined with caffeine (COM)
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Jose Manuel Jurado Castro
Alcohol Abuse/Dependence
Examining the Relationship Between Physical Activity Levels and Chronotype Tendencies in Individuals With Alcohol Dependence
Alcohol use disorders are characterized by excessive alcohol consumption and loss of control and are associated with high mortality and disease burden.
- Trial name
- NCT06850428
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Gulhane School of Medicine
Respiratory Distress Syndrome in Premature Infant, RDS of Prematurity
Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa
The goal of this pragmatic clinical trial is to learn if the drug surfactant given by a less invasive technique works to treat respiratory distress in preterm infants in low- and middle-income African countries where invasive…
- Conditions
- Respiratory Distress Syndrome in Premature Infant, RDS of Prematurity, Surfactant Deficiency Syndrome Neonatal, Premature Birth
- Trial name
- NCT06554522
- Testing
- Surfactant
- Where
- 8 sites in Central African Republic, Ghana and 2 more
- Volunteers
- 1,512 people
- Sponsor
- Indiana University
Vascular Function
Effect of Black Tea on Vascular Function
Epidemiological studies indicate that regular consumption of three cups of black tea per day reduces the risk of stroke or myocardial infarction.
- Trial name
- Heraclitus (NCT01945970)
- Testing
- Black tea extract, Positive control
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Neoplasms
Pharmacokinetic Drug-Drug Interaction Study of Rucaparib
The purpose of this study is to assess pharmacokinetic concentrations of multiple probes alone followed by assessment of the same drug pharmacokinetic concentrations when the patient has steady-state exposure to rucaparib…
- Trial name
- DDI (NCT02740712)
- Testing
- Caffeine, Warfarin, Omeprazole
- Where
- 3 sites in Poland
- Volunteers
- 17 people
- Sponsor
- pharmaand GmbH
Alcoholic Liver Cirrhosis
REVIVE(Randomized Exploratory Clinical Trial to Evaluate the Safety and Effectiveness of Stem Cell Product in Alcoholic Liver Cirrhosis Patient)
If the participant voluntarily agrees to participate in the clinical trial before registration, the investigator conducts a screening test to evaluate the participant's suitability.
- Trial name
- NCT01875081
- Testing
- Livercellgram
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Pharmicell Co., Ltd.
Depressive Disorder
Bupropion & Cardio Birth Defect (Slone)
Bupropion is a unique drug that is used both to treat depression and as an aid in smoking cessation. In 2008, the final report from the Bupropion pregnancy registry described 24 congenital malformations among the 675 women…
- Trial name
- NCT01597661
- Testing
- Exposure to any bupropion during the first trimester, Exposure to bupropion alone during the first trimester, Referent group: no exposure to any anti-depressant or anti-smoking drug during pregnancy
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
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