Clinical trials: Caffeine, completed
Atopic Dermatitis
Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4
The purpose of this trial is to investigate if tralokinumab changes the metabolism of selected CYP substrates in adults with moderate-to-severe AD after: 14 weeks of treatment with tralokinumab a single dose of tralokinumab
- Trial name
- NCT03556592
- Testing
- Tralokinumab, Caffeine, Warfarin
- Where
- 12 sites in United States, France and 1 more
- Volunteers
- 40 people
- Sponsor
- LEO Pharma
Pulmonary Embolism, Deep Vein Thrombosis
Multi-Center Human Alert Trial to Prevent DVT and PE
To evaluate physician response to human alerts that inform the clinician that his/her patient may be eligible for thromboprophylaxis.
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Cancer, Surgery
- Trial name
- NCT00409136
- Testing
- Human Alert
- Where
- 26 sites in United States
- Volunteers
- 2,496 people
- Sponsor
- Brigham and Women's Hospital
Dysmenorrhea
Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)
This is a study to determine the overall analgesic effect of a single oral dose of etoricoxib compared to ibuprofen in participants with moderate-to-severe primary dysmenorrhea.
- Trial name
- NCT01462370
- Testing
- Etoricoxib, Ibuprofen, Acetaminophen 250 mg, isopropylantipyrine 150 mg and anhydrous caffeine 50 mg
- Volunteers
- 139 people
- Sponsor
- Organon and Co
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Firefighters work some of the most demanding schedules known under highly stressful and demanding conditions. The need to work frequent extended shifts and long work weeks leads to acute and chronic partial sleep deprivation as…
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01988129
- Testing
- Sleep disorders education and screening
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
L-theanine
Theanine and Caffeine on Neurophysiology of Attention
L-theanine and caffeine are nutritional compounds that are naturally found in tea. Our recent findings using an EEG paradigm are consistent with the findings of others, indicating that intake of L-theanine and caffeine reduce the…
- Trial name
- THECNA (NCT02770105)
- Testing
- Theanine, Caffeine, Theanine-Caffeine Combination
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Caffeine Dependence, Anxiety
Remote Guided Caffeine Reduction
The purpose of this online research study is to determine whether or not a gradual caffeine reduction program developed at Johns Hopkins can help people reduce their caffeine use.
- Conditions
- Caffeine Dependence, Anxiety, Sleep Disturbance, Gastrointestinal Dysfunction
- Trial name
- NCT04560595
- Testing
- Caffeine Reduction Manual
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Clinical Deterioration, Hospital Medicine
Realtime Streaming Clinical Use Engine for Medical Escalation
The escalation of care for patients in a hospitalized setting between nurse practitioner managed services, teaching services, step-down units, and intensive care units is critical for appropriate care for any patient.
- Conditions
- Clinical Deterioration, Hospital Medicine, Monitoring, Physiologic
- Trial name
- ReSCUE-ME (NCT04026555)
- Testing
- MEWS++ Monitoring, Predictor Score
- Where
- United States
- Volunteers
- 2,780 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Asymptomatic Conditions
Effects of Caffeine and Coffee on Resting Metabolic Rate, Comparing Normal Weight Men to Obese Men
Background. The prevalence of obesity has increased in the last two decades. To maintain body weight energy expenditure (EE) should be equal to energy intake (EI).
- Trial name
- RMR (NCT02751840)
- Testing
- Caffeine, Coffee, Decaffeinated
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Cognitive Function and Memory
Cognitive Effects of a Dietary Supplement With PQQ, GABA, Caffeine, and B-Vitamins in Healthy Postmenopausal Women: A Randomized Controlled Trial
Various food supplements have been shown to improve cognitive function. However, there is limited data on the impact of these supplements on postmenopausal women.
- Trial name
- NCT06748989
- Testing
- Cortexium food supplement
- Where
- Hungary
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- FEMPHARMA Kft.
Healthy
Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464
A two part, fixed-sequence, open-label crossover study to evaluate potential CYP1A2-mediated drug-drug interactions of ABX464 in healthy subjects using caffeine and fluvoxamine as probe drugs
- Trial name
- NCT05121714
- Testing
- Caffeine, ABX464, Fluvoxamine
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Abivax S.A.
Mood
Effects of Theobromine and Caffeine on Mood, Cognition and Blood Pressure
The purpose of this study was to measure potential mood, cognition and blood pressure effects of theobromine and caffeine in healthy women
- Trial name
- NCT01288547
- Testing
- theobromine, Caffeine, caffeine + theobromine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Sodium, Caffeine
Study on Sodium and Caffeine in Children and Adolescents
This study will compare different methods (24 hour urine collection, evening and morning spots, and questionnaires) to measure the consumption of sodium and cafeine in children and adolescents.
- Trial name
- NCT02900261
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Postoperative Ileus, Caffeine
Can Coffee/Caffeine Improve Post-Operative Gastrointestinal Recovery
Disruption of the normal gastrointestinal (GI) motility is a well-known consequence of major surgery. The pathophysiology behind this phenomenon is not fully understood but involves the autonomic nervous system as well as a…
- Trial name
- NCT04547868
- Testing
- Coffee, Decaffeinated Coffee, Warm water
- Where
- 3 sites in Canada
- Volunteers
- 174 people
- Sponsor
- Sunnybrook Health Sciences Centre
Atrial Fibrillation, Heart Failure
A Mechanistic Exploratory Study of AF-induced Cardiac Dysfunction and Symptoms
Although the heart rhythm disorder Atrial Fibrillation (AF) affects 2% of the population, the impact it has on an effected individual can be highly variable.
- Trial name
- NCT04987723
- Testing
- Holter monitoring, stress echocardiography, Cardiac MRI
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- Barts & The London NHS Trust
Delirium
Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR)
This is a pilot randomized controlled trial that will test whether a multicomponent decision support system will improve the postoperative environment for neurocognitive and clinical recovery in older, high-risk surgical…
- Trial name
- NCT04007523
- Testing
- Family Support System, HELP Support System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Anaerobic Performance Neuromuscular Performance Cognitive Performance
Low-Dose Caffeine and Taurine Effects on Performance
This study aims to investigate the effects of low-dose caffeine and taurine, administered separately and in combination, on anaerobic, neuromuscular, and cognitive performance.
- Trial name
- CATAP (NCT07466654)
- Testing
- Caffeine, taurine, Caffeine + Taurine
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara University
Exercise Performance, Physical Performance
Effects of Different Caffeine Forms on Aerobic and Anaerobic Exercise Performance
This study investigated the effects of different caffeine delivery forms on aerobic and anaerobic exercise performance in healthy adults.
- Trial name
- NCT07497685
- Testing
- Comparative Acute Effects of Caffeine Delivery Forms (Capsule, Chewing Gum, Mouth Rinse) on Aerobic Capacity and Wingate Anaerobic Performance Outcomes in Recreational Male Athletes: A Randomized Coun
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Nocturia
The Effect of Combined Systematized Behavioural Modification Education Program (SyBeMeP) With DDAVP in Patients With Nocturia
In patients with nocturia, combinational treatment of DDAVP and SyBeMeP might show better outcomes. Systemic video instruction might prove to be beneficial by helping patients have better understanding on treatment and replacing…
- Trial name
- NCT01576900
- Testing
- SyBeMeP (Systemized Behavioural Modification education Program)
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Healthy
Genetic Information and Dietary Intake Behaviour
This study's primary objective is to determine if providing individuals with personal genetic information impacts dietary intake behaviour.
- Trial name
- NCT01353014
- Testing
- Dietary advice with genetic information, General dietary recommendations
- Where
- Canada
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood
The trial will be performed to assess the influence of BI 730357 on the pharmacokinetics of caffeine, warfarin, omeprazole and midazolam.
- Trial name
- NCT04679948
- Testing
- Percoffedrinol®, Coumadin®, Antra MUPS®
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim