Clinical trials: Conventional therapy
Head and Neck Cancer
Bevacizumab, Docetaxel, and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00281840
- Testing
- bevacizumab, docetaxel, conventional surgery
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Case Comprehensive Cancer Center
Cerebral Palsy, Functional Balance
Effects of Virtual Reality on Functional Balance in Children With Cerebral Palsy (GMFCS III-IV)
This study proposes a randomized clinical trial to evaluate the effectiveness of an immersive virtual reality (VR)-based rehabilitation intervention on functional balance in children and adolescents (5-20 years) with cerebral…
- Trial name
- NCT07078279
- Testing
- immersive virtual reality intervention with Meta Quest 3, Intervention with Conventional Balance Physical Therapy
- Volunteers
- 40 people
- Sponsor
- Bartolome Puerta Arroyo
Crohn's Disease
Early Immunosuppressants in Crohn's Disease
Pluricentric randomized study comparing two therapeutic strategies at beginning of Crohn's disease: early immunosuppressants (prescription within the six first months following diagnosis) vs.
- Trial name
- RAPID (NCT00546546)
- Testing
- early immunosuppressants (azathioprine, methotrexate)
- Where
- 26 sites in France
- Volunteers
- 120 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Cardiogenic Shock
The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock Patients
Extracorporeal membrane oxygenation (ECMO) is a temporary mechanical circulatory support device for cardiogenic shock (CS) patients.
- Trial name
- NCT02870946
- Testing
- Simultaneous RRT, Standard care
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Beijing Anzhen Hospital
Negative-Pressure Wound Therapy, Diabetic Foot
Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
- Trial name
- NCT05716503
- Testing
- Negative Pressure Wound Therapy (NPWT), Ordinary dressings with antibiotic ointment and gauze
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Dental Pain, Dental Anxiety and Child Behavior Are Assess in Response to Dental Injection
Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children
This randomized controlled trial aims to compare the effectiveness of Computer-Controlled automatic injection device versus conventional injection techniques in pediatric dental patients.
- Trial name
- NCT07193342
- Testing
- computer controlled automatic injection (Star pen® system), conventional anesthetic syringe
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Future University in Egypt
Hepatocellular Carcinoma, Hepatic Chemotherapy
HAIC Compared With TACE in Huge Hepatocellular Carcinoma
This study intends to compare the efficacy of transcatheter arterial chemical embolization (TACE) with hepatic arterial infusion chemotherapy (HAIC) for patients with intermediate-advanced huge hepatocellular carcinoma.
- Conditions
- Hepatocellular Carcinoma, Hepatic Chemotherapy, Liver Cancer
- Trial name
- NCT06641713
- Testing
- TACE, HAIC
- Where
- China
- Volunteers
- 664 people
- Sponsor
- Sun Yat-sen University
Colon Carcinoma Metastatic in the Liver, Colorectal Adenocarcinoma
VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer
This randomized phase I trial studies how well anti-semaphorin 4D (anti-SEMA4D) monoclonal antibody VX15/2503 with or without ipilimumab or nivolumab work in treating patients with stage I-III pancreatic cancer that can be…
- Conditions
- Colon Carcinoma Metastatic in the Liver, Colorectal Adenocarcinoma, Pancreatic Adenocarcinoma, Resectable Pancreatic Carcinoma
- Trial name
- NCT03373188
- Testing
- Anti-SEMA4D Monoclonal Antibody VX15/2503, Ipilimumab, Nivolumab
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Sleep Apnea
Long-term Effect of the Physical Activity Promotion on the Clinical Characteristics and Vascular Risk in Patients With Mild-moderate Obstructive Sleep Apnea
Main objective: To assess the effect of the daily physical activity promotion with a pedometer during 12 months on the apnea-hypopnea index (AHI) in patients with mild to moderate obstructive sleep apnea (OSA). Study patients.
- Trial name
- PASOS (NCT03086850)
- Testing
- Promotion of daily physical activity with a pedometer, Conventional treatment
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Hospital Universitario La Paz
Colorectal Cancer Survivor, Rehabilitation
Multidimensional Rehabilitation Intervention in Colorectal Cancer Survivors
A metaverse-based multidimensional rehabilitation program will be implemented for colorectal cancer survivors who have undergone curative surgery and adjuvant therapy.
- Conditions
- Colorectal Cancer Survivor, Rehabilitation, Quality of Life
- Trial name
- NCT05956990
- Testing
- multidimensional rehabilitation
- Volunteers
- 60 people
- Sponsor
- Qu Shen
Hepatitis B, Acute-On-Chronic Liver Failure
RL-1 Novel Human-derived Bio-artificial Liver Treatment in Patients of HBV Related ACLF
This study is to investigate the clinical efficacy and safety of RL-1 Novel Human-derived Bio-artificial Liver treatment in patients with Hepatitis b virus related acute-on-chronic liver failure.
- Trial name
- NCT04195282
- Testing
- Plasma exchange, RL-1 Novel Human-derived Bio-artificial Liver Treatment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Helicobacter Infection
Standard Triple Therapy vs Sequential Therapy in Treatment of H Pylori Infection
Traditionally, H pylori infection has been treated with conventional triple therapy. This includes amoxicillin, clarithromycin and a proton pump inhibitor all given daily for 10-14 days.
- Trial name
- NCT01723059
- Testing
- Standard Triple Therapy, Sequential Therapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Dallas VA Medical Center
Obesity, Obesity, Morbid
Luso-Cor Stent Compared to Other Endoscopic Techniques for Management of Fistulas and Anastomotic Dehiscences(ES-LCCE-UDFM)
The global prevalence of obesity has prompted an increase in bariatric surgery, which is the only management strategy that provides long-term weight loss and improvement of obesity-related diseases.
- Conditions
- Obesity, Obesity, Morbid, Esophageal Cancer, Esophageal Neoplasms
- Trial name
- ES-LCCE-UDFM (NCT06862479)
- Testing
- Endoscopic management of fistulas with stents or vacum therapy
- Where
- Portugal
- Volunteers
- 180 people
- Sponsor
- Unidade Local de Saúde Santa Maria
Temporomandibular Joint Dysfunction Syndrome, Forward Head Posture
Efficacy of Scapulothoracic Exercises on Postural Stability, Proprioception, Muscular Features and Mandibular Functions
The goal of this Randomized, Double-Blind, Clinical Trial is to investigate the effects of scapulothoracic exercises on postural stability, muscle strength, muscular endurance, mandibular functions and proprioception in sedentary…
- Trial name
- NCT05966103
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Cyprus International University
Brain Cancer
3D Printed Mask for GBM and Brain Mets
This is a single site, investigator initiated study that aims to explore the feasibility of using a personalized 3D printed immobilization mask for CNS patients undergoing radiation therapy.
- Trial name
- NCT04114786
- Testing
- 3D-printed mask, Thermoplastic mask
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Adhesive Capsulitis
Effects of Conventional Physical Therapy With and Without Scapular Stabilization Exercises in Adhesive Capsulitis.
The objective of this study will be to determine the Effects of conventional physical therapy with and without scapular stabilization exercises on pain, function, scapular dyskinesia, and proprioception in patients with adhesive…
- Trial name
- NCT05403918
- Testing
- conventional physiotherapy, scapular stabilization exercises along with conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Aggressive Periodontitis
Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
The purpose of this study is to determine whether full-mouth disinfection is effective in the initial periodontal treatment of generalized aggressive periodontitis on clinical parameters, gingival crevicular fluid interleukin-1β…
- Trial name
- NCT02466646
- Testing
- Klorhex® Gel, rinse and spray, Conventional IPT, Full-mouth IPT
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hemodialysis
Aerobic Exercises and Hemodialysis Patients
Patients undergoing hemodialysis (HD) frequently exhibit elevated serum uric acid (SUA) levels, which are associated with cardiovascular risks, joint issues, and diminished quality of life (QoL).
- Trial name
- NCT07076888
- Testing
- Aerobic Exercises, Conventional Program
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Procedural Pain, Congenital Heart Disease
Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease
The aim of this prospective randomized controlled trial is to evaluate therapeutic hypnosis as a co-analgesia in thoracic drain removal in children with congenital heart disease.
- Conditions
- Procedural Pain, Congenital Heart Disease, Heart Surgery, Hypnosis
- Trial name
- PEACE-HYPNO (NCT06373627)
- Testing
- Hypnosis, Conventional medications used for sedation-analgesia, Medications used in addition to hypnosis
- Volunteers
- 104 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Knee Osteoarthritis
Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis
This is a single-center, prospective, randomized, single-blind, comparator therapy, parallel group study for symptomatic patients diagnosed with knee osteoarthritis.
- Trial name
- NCT03491761
- Testing
- PRP Treatment, HA Treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Endeavor Health
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