Clinical trials: Conventional therapy
Scheuermann's Kyphosis
Prospective Study of Scheuermann's Kyphosis
The purpose of this study to determine the radiographic and clinical outcomes of spinal deformity surgical treatment in patients with Scheuermann's Kyphosis.
- Trial name
- PSK (NCT00738309)
- Where
- 9 sites in United States, Germany
- Volunteers
- 147 people
- Sponsor
- Setting Scoliosis Straight Foundation
Postural Alignment, Idiopathic Adolescent Scoliosis
Artificial Intelligence-Based Postural Feedback for Scoliosis
Due to advancements in technology, Posture-Analyzing and Virtual Reconstructing (PAViR) systems were developed. They used Red-Green-Blue-Depth camera sensors and artificial intelligence to evaluate human posture alignment, muscle…
- Trial name
- NCT07669428
- Testing
- Postural feedback, Physical therapy for scoliosis
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Mandibular Fractures
Customized z Shaped Miniplate Versus Standard 2 Miniplates for Fixation of Parasymphyseal/Body Mandibular Fractures
Mandibular fractures are a common type of facial fractures. The surgical treatment has developed over the years due to improved understanding of biomechanics, biomaterials and scientifically based treatment outcomes.
- Trial name
- NCT07094867
- Testing
- customized Z shaped miniplate, conventional two miniplates
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Hams Hamed Abdelrahman
Unruptured Intracranial Aneurysm, Stents
Application of Platelet Function Test in Prevention of Ischemic Events After Stent Placement in Intracranial Aneurysms
This study was designed to identify high platelet reactivity (HPR) who might have in-stent thrombosis in unruptured aneurysm with intracranial stent placement with light transmittance platelet aggregometry (LTA).
- Conditions
- Unruptured Intracranial Aneurysm, Stents, Antiplatelet Drugs
- Trial name
- APISIA Trail (NCT03989557)
- Testing
- Aspirin and clopidogrel/Ticagrelor, Light transmittance aggregometry
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Beijing Neurosurgical Institute
Breast Cancer Survivors
The Effect of Myofascial Chain Release Techniques on Shoulder Joint Range of Motion in Breast Cancer Survivors
In breast cancer patients, limitation of shoulder joint movement occurs following mastectomy surgery. Studies have reported that damage to the fascia on the pectoralis major muscle during mastectomy surgery contributes to the…
- Trial name
- NCT05386628
- Testing
- conventional physiotherapy, Manual lymphatic drainage, Myofascial relasing
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Medeniyet University
Diabetic Peripheral Neuropathic Pain (DPN)
Hyperbaric Oxygen Therapy Versus High Power Laser for Diabetic Neuropathy
The purpose of this study is to compare the clinical effects of Hyperbaric Oxygen Therapy (HBOT) versus High-Intensity Laser Therapy (HPLT) on sensorimotor functions and nerve conduction in patients suffering from painful…
- Trial name
- HBOT-HPLT-DPN (NCT07848867)
- Testing
- Conventional Physiotherapy Program, Hyperbaric Oxygen Therapy, High-Intensity Laser Therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
SLE - Systemic Lupus Erythematosus
The Primary Objective of the Trial is to Evaluate the Effect of the Addition of Belantamab Mafodotin to Standard of Care Therapy on the Titres of Serum Anti-dsDNA Antibodies in Patients With Previously Treated SLE.
The primary objective of the trial is to evaluate the effect of the addition of belantamab mafodotin to standard of care therapy on the titres of serum anti-dsDNA antibodies in patients with previously treated SLE.
- Trial name
- Bela-SLE (NCT07844200)
- Testing
- belantamab mafodotin to the existing stable standard background therapy
- Volunteers
- 12 people
- Sponsor
- Medical Association for the Study of Cancer Biology and Treatment
Parkinson Disease, Neuro-Degenerative Disease
Conventional Physical Therapy Action Observation Therapy on Freezing of Gait and Functional Mobility in Parkinson's Disease
The goal of this study is to determine the effects of action observation therapy with conventional physical therapy on freezing gait and functional limitation in participants with Parkinson's disease.
- Trial name
- NCT07244900
- Testing
- Conventional Physical Therapy, Action Observation plus conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- University of Lahore
Hypoxemia
Comparative Study on the Effectiveness, Comfort and Compliance of HFNC and Noninvasive Mechanical Ventilation BiPAP Mode in the Treatment of Hypoxemia Patients
Patients who met the inclusion criteria were included and signed an informed consent form, which complied with the requirements of the ethics committee of our unit. All subjects were inpatients.
- Trial name
- NCT05784636
- Testing
- Non-invasive BiPAP ventilation, HFNC
- Where
- China
- Volunteers
- 243 people
- Sponsor
- Qilu Hospital of Shandong University
Breast Cancer
Neoadjuvant SBRT Followed by Nab-Paclitaxel Combined With Toripalimab in HR+/HER2- Breast Cancer
The goal of this clinical trial is to evaluate the efficacy and safety of neoadjuvant stereotactic body radiotherapy (SBRT) followed by nab-paclitaxel combined with toripalimab in patients with previously untreated…
- Trial name
- NCT06914440
- Testing
- Stereotactic Body Radiation Therapy (SBRT), Toripalimab, Neoadjuvant Chemotherapy
- Where
- 2 sites in China
- Volunteers
- 27 people
- Sponsor
- Xijing Hospital
Venous Leg Ulcer
Treatment Outcome of Autologous PRP Versus Conventional Therapy Among Patients With Chronic Venous Leg Ulcers
The use of PRP has dramatically increased in the fields of orthopedics, spine surgery, reconstructive plastic surgery, oral and maxillofacial surgery, and dermatological indications.
- Trial name
- NCT05974982
- Testing
- PRP, Conventional therapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Breast Ductal Carcinoma In Situ
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
This phase Ib trial studies the side effects and best dose of a vaccine called H2NVAC before surgery in treating patients with HER2 expressing ductal carcinoma in situ.
- Trial name
- NCT04144023
- Testing
- Granulocyte-Macrophage Colony-Stimulating Factor, Multi-epitope HER2 Peptide Vaccine H2NVAC, Therapeutic Conventional Surgery
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Mayo Clinic
Burn Injury
Effects of Non-Invasive Vagus Nerve Stimulation in Adolescent Burn Patients
This study will evaluate the effects of non-invasive vagus nerve stimulation in adolescents aged 12 to 18 years who have burn injuries.
- Trial name
- NCT07566923
- Testing
- Non-Invasive Vagus Nerve Stimulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fenerbahce University
Chronic Mechanical Neck Pain
Bruegger's Relief Exercise in Chronic Mechanical Neck Pain
The aim of this randomized controlled trial is to determine the effect of Bruegger's Relief Exercise combined with conventional physical therapy on pain intensity, functional disability, cervical range of motion, and…
- Trial name
- NCT07791680
- Testing
- Bruegger's Relief Exercise + Conventional Physical Therapy, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Rheumatoid Arthritis
Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheumatoid Arthritis
Rheumatoid arthritis is a systemic autoimmune disease characterized by inflammatory synovitis and progressive joint destruction, which are associated with severe disability and increased mortality.
- Trial name
- NCT05567380
- Testing
- Observation
- Volunteers
- 150 people
- Sponsor
- Sohag University
Thoracic
Effects of Thoracic Extension Versus Thoracic Stabilization Exercises in Patients With Maigne's Thoracic Pain
The aim of this study is to compare the effects of thoracic extension versus thoracic stabilization exercises on pain, stiffness, range of motion, disability and posture in patients with Maigne's thoracic pain.This study will be…
- Trial name
- NCT05395078
- Testing
- Conventional physical therapy treatment along with thoracic extension exercises, Conventional physical therapy treatment along with thoracic stabilization exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Vitiligo Vulgaris, Psoriasis
PALLAS Laser for Skin Diseases
The primary objective of this study is to get clinical experiences with the PALLAS laser in the treatment of skin conditions that respond well to UV light (vitiligo, psoriasis, alopecia areata, atopic dermatitis).
- Conditions
- Vitiligo Vulgaris, Psoriasis, Alopecia Areata, Atopic Dermatitis
- Trial name
- PALLAS-UV (NCT07250997)
- Testing
- UVB laser treatment
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Szeged University
Parkinson Disease
Dance Well Therapy: a Study for Evaluating Efficacy, Safety, and Feasibility
A new and in-teresting complementary approach for rehabilitation of parkinsonian patients is represented by "Dance Well", which is an artistic, multisensory dance intervention based on art and music.
- Trial name
- DWpsVMF (NCT06896123)
- Testing
- Dance Well: an artistic, multisensory dance intervention based on art and music, Conventional motor therapy group
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa di Cura Villa Margherita Fresco
Solid Tumor, Advanced Solid Tumor
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
A national, prospective, multi-center, open-label, multi-cohort study comprised of a framework to screen patients for actionable targets and evaluation of molecular profiling guided therapy recommended by MTB based on genomic…
- Conditions
- Solid Tumor, Advanced Solid Tumor, Metastatic Cancer
- Trial name
- KOSMOSII (NCT05525858)
- Testing
- Alectinib, Atezolizumab, Erlotinib
- Where
- 32 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Bundang Hospital
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