Clinical trials: Experimental Group
Health Literacy
Psychoeducational Intervention to Promote Adolescents' Mental Health Literacy in a School Context
Mental Health Literacy was defined as knowledge and beliefs about mental disorders that aid in its recognition, management or prevention.
- Trial name
- NCT03872817
- Testing
- Intervention ProLiSMentAl
- Volunteers
- 38 people
- Sponsor
- Escola Superior de Enfermagem de Coimbra
Cancer, Cancer-Related Syndrome
Effects of a Multimodal Physical Exercise and Functional Rehabilitation Program on Fatigue, Pain, Functional Capacity and Quality of Life in Cancer Patients With Tumor Asthenia.
Tumor asthenia is the most common symptom associated with cancer and its treatment. Although the estimated prevalence varies between 60-90%, and it is considered the longest-lasting symptom in cancer patients, having the greatest…
- Conditions
- Cancer, Cancer-Related Syndrome, Fatigue
- Trial name
- NCT04761289
- Testing
- Multimodal Exercise and Functional Rehabilitation Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Dysplasia; Hip
Spica Cast Duration for DDH
This study looks at treatment for developmental dysplasia of the hip (DDH), a condition where there is abnormal development of a child's hip joint.
- Trial name
- NCT06204068
- Testing
- Spica cast, Rhino brace
- Where
- United States
- Sponsor
- Yale University
Cocaine Dependence, Alcohol Dependence
HBPL Study of the Impact of the NK1 Antagonist Aprepitant
The proposed research will focus on investigating the determinants and consequences of CAD via measurement of physiological, behavioral and subjective effects of physiologic and psychologic stress cues in CAD volunteers in the…
- Trial name
- NCT01176591
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pennsylvania
Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate
Safety, Dosage, and Microbiome Engraftment Study of MGT-006 for Ulcerative Colitis (ROOT Study)
Ulcerative colitis is a condition that causes inflammation and ulcers in the large intestine. MGT-006 is an investigational oral capsule containing viable gut microbiota from screened human donors.
- Trial name
- ROOT (NCT07913347)
- Testing
- MGT-006, Vancomycin hydrochloride, Amoxicillin hydrate/ Fosfomycin calcium hydrate/ Metronidazole
- Where
- 12 sites in United States, Japan
- Volunteers
- 54 people
- Sponsor
- Metagen Therapeutics, Inc.
Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe
Effect of NMES on Quadriceps Muscle Strength and Endurance in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a respiratory condition that results in a mixture of small airway disease and parenchymal destruction, changes that are characteristic of emphysema.
- Conditions
- Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe, Acute Exacerbation of COPD
- Trial name
- NMES (NCT05539547)
- Testing
- Neuromuscular Electrical Nerve Stimulation, Usual Physiotherapy treatment (Chest Physiotherapy and mobility)
- Volunteers
- 140 people
- Sponsor
- Randall Debattista
Hypertension, Cognitive Decline
The Heart & Mind Study
Older adults with subjective cognitive decline (SCD) may represent a portion of the population experiencing early sings of cognitive decline. Systolic hypertension is a major contributor to cognitive impairment.
- Conditions
- Hypertension, Cognitive Decline, Vascular Cognitive Impairment
- Trial name
- NCT03545958
- Testing
- High-intensity Interval Training (HIT), Moderate-intensity Continuous Training (MCT)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Western University, Canada
Insomnia, Major Depressive Disorder
Using Sleep Wearables to Adapt Cognitive-behavioral Therapy for Insomnia in the Context of Depression (CBTiA)
This study aims to better adapt cognitive behavioral therapy for insomnia (CBTi) for people with comorbid depression by using objective sleep measures to tailor the behavioral interventions components of CBTi.
- Conditions
- Insomnia, Major Depressive Disorder, Persistent Depressive Disorder
- Trial name
- CBTiA (NCT05990855)
- Testing
- eCBTi-obj, eCBTi-subj
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University of Ottawa
Chronic Kidney Disease, Pulmonary Embolism
Safety of Low Dose IV Contrast CT Scanning in Chronic Kidney Disease
The purpose of this study is to show that the use of low volume iso-osmolar non-ionic radio contrast medium (30 cc) in a thoracic CT Scanning procedure in a selected group of patients with chronic kidney disease (CKD) will avoid…
- Conditions
- Chronic Kidney Disease, Pulmonary Embolism, Renal Artery Stenosis, Pulmonary Cancer
- Trial name
- NCT02476526
- Testing
- Low Volume iso-osmolar non-ionic radio contrast medium, Acetylcysteine Inhalation, Sodium Bicarbonate Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Allergic Rhinitis
Effect of Home Environment Regulation on Symptom Control and Quality of Life in Children With Allergic Rhinitis
The purpose of this study is to examine the effect of nursing intervention to regulate the home environment on symptom control and quality of life in children with allergic rhinitis.
- Trial name
- NCT04479085
- Testing
- nursing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Hypothermia, Trauma, Psychological
Warm-up Efficiency by Body Warmer Versus Standard Procedure in Severely Traumatized Patients
Study of adult patients with severe all-cause trauma having a body temperature less than 36°Celsius (C) that is managed by a Mobile Emergency Service team and oriented towards a Vital Emergency Room.
- Trial name
- THERMOTRAUMA (NCT03970915)
- Testing
- Body warmer, Standard warming procedure
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Hospices Civils de Lyon
Autism Spectrum Disorder, Intellectual Disability
Facing Your Fears: Adolescents With ASD and Intellectual Disability
Adolescents with ASD and intellectual disability (ID) are a complex and underserved population. Approximately 50% of individuals with ASD/ID experience significant anxiety.
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Anxiety, Emotion Regulation
- Trial name
- FYF:ASD/ID (NCT05131425)
- Testing
- Facing Your Fears: ASD/ID, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV
The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo
CUT*HIVTHER 001 is a randomised placebo-controlled Phase I/II study aimed at exploring the safety and immunogenicity of two different modes of delivery of a GTU® DNA plasmid vaccine (GTU®-multiHIV B clade) in HIV infected…
- Trial name
- CUTHIVTHER001 (NCT02457689)
- Testing
- GTU®-MultiHIV B Clade Vaccine, Sodium chloride BP
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Pain
Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty
This study will determine whether a drug called sodium nitrite helps improve pain and post-operative recovery associated with knee replacement surgery.
- Trial name
- NCT05893160
- Testing
- JAN101 SR
- Sponsor
- University of Alabama at Birmingham
Parkinson Disease
Effects of Home-based High-speed Bodyweight Resistance Training in Individual With Parkinson's Disease
Exercises that involve increasing the speed of movements are beneficial for individuals with Parkinson's disease (PD) and have the potential to reduce bradykinesia and improve mobility.
- Trial name
- NCT06646523
- Testing
- High-speed bodyweight resistance training, Control group (Bodyweight intervention, usual speed)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Federal University of Minas Gerais
Disability
Vermont RETAIN Impact Evaluation
The Retaining Employment and Talent after Injury/Illness Network (RETAIN) demonstration is a collaborative effort between the U.S.
- Trial name
- NCT05146362
- Testing
- Vermont RETAIN
- Where
- United States
- Volunteers
- 798 people
- Sponsor
- Mathematica Policy Research, Inc.
Shoulder Injuries, Pain, Postoperative
Battlefield Acupuncture Following Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to standard post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation…
- Conditions
- Shoulder Injuries, Pain, Postoperative, Acupuncture, Ear, Pain Management
- Trial name
- BFA (NCT04094246)
- Testing
- Battlefield Acupuncture, Standard post-surgical rehabilitation
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Keller Army Community Hospital
Delinquency, Externalizing Behavior
The Effectiveness of a Dutch Program in Preventing Criminal Exploitation
The purpose of this study is to investigate whether the prevention program 'Buit in de Klas' is effective.
- Trial name
- NCT07157761
- Testing
- Buit in de klas
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Utrecht University
Acquired Brain Injury
Exercise Therapy Program on Acquired Brain Injury
In this study, the physical and psychosocial effects of a exercise therapy and adapted physical activity program based on racket sports for ambulant people with acquired brain injury will be investigated.
- Trial name
- NCT05358470
- Testing
- Exercise therapy and adapted physical activity-based program
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidade da Coruña
Hepatocellular Carcinoma
The Combination Effect of Statin Plus Metformin on Relapse-free
The study demonstrated that either statin or metformin served as notable use in reducing the incidence of many cancers.
- Trial name
- NCT02819869
- Testing
- Statin and Metformin use
- Where
- Taiwan
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
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