Clinical trials: Experimental Group
Nerve Block
Opioid-Free Pain Management After NUSS Surgery in Adolescents
The investigators applied ultrasound-guided bilateral transverse thoracic fascia block combined with intercostal nerve block-a previously unreported analgesic approach for post-thoracic surgery-to NUSS patients.
- Trial name
- NCT07288424
- Testing
- Nerve block
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Qin Zhang
Hepatocellular Carcinoma
A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
The goal of this clinical trial is to evaluate the efficacy and safety of camrelizumab plus apatinib as adjuvant therapy for patients with hepatocellular carcinoma at high risk of recurrence after radical resection or ablation.
- Trial name
- NCT06546280
- Testing
- Camrelizumab, Apatinib
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Zhujiang Hospital
Pediatric
The Effect of Education on Nurses' Knowledge About High-flow Nasal Cannula Oxygen Therapy
This study was conducted to evaluate the oxygen therapy methods used in pediatric services and to specify the roles and responsibilities of nurses in the application of HFNC, which is one of these methods.
- Trial name
- NCT05362279
- Testing
- Training
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Acinetobacter Baumannii-calcoaceticus Complex, Hospital-acquired Bacterial Pneumonia
Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex
This is a 2-part study, with Part A being the randomized, controlled portion of the study in patients with ABC hospital-acquired bacterial pneumonia (HABP), ventilator-associated bacterial pneumonia (VABP), or bacteremia.
- Conditions
- Acinetobacter Baumannii-calcoaceticus Complex, Hospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia, Bacteremia
- Trial name
- ATTACK (NCT03894046)
- Testing
- Sulbactam, Durlobactam, Colistin
- Where
- 90 sites in United States, Belarus and 15 more
- Volunteers
- 207 people
- Sponsor
- Entasis Therapeutics
Autism Spectrum Disorder
Early Intervention and Autism: Transformation From Research to Practice Through a Competency Based Model
This study evaluates the effect of a competency based model on program quality in Swedish preschools for Children with autism spectrum disorder (ASD).
- Trial name
- AUT-TID (NCT03634761)
- Testing
- Competency based model, Comprehensive program
- Where
- 2 sites in Sweden
- Volunteers
- 17 people
- Sponsor
- Stockholm University
Alcohol Use Disorder Cognitive Decline
NEUROPSYCHOLOGICAL REHABILITATION FOR ALCOHOL USE DISORDERS
This investigation will take place between September 2024 and June 2025, with the objective of analyzing executive deficits and the impact of Neuropsychological Rehabilitation on Alcohol Use Disorder, comparing different…
- Trial name
- AUD (NCT06933186)
- Testing
- Neuropsychological rehabilitation, Weekly therapeutic groups
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- University of Lisbon
Mental Health Issue
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
This study will assess how different types of training and support influence the way that school staff understand, and respond to, the mental and behavioral health needs of middle school students.
- Trial name
- E-IMPACTS (NCT06047041)
- Testing
- EIS Only, EIS + ECHO
- Where
- 3 sites in United States
- Volunteers
- 21,350 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Inguinal Hernia, Postoperative Pain
TENS for Pain and Sleep After Hernia Surgery
This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Sleep Disturbance
- Trial name
- TENS-HERNIA (NCT07319754)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Post-Concussion Syndrome, Traumatic Brain Injury
Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS)
Objective/Hypothesis: An eight-week course of forty low-pressure Hyperbaric Oxygen Treatment's (HBOT's) can significantly improve symptoms and cognitive function in subjects with the persistent-post concussion syndrome (PPCS) of…
- Trial name
- NCT02089594
- Testing
- Hyperbaric Oxygen, No Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Prostate Cancer
Evaluation of Post-operative Biochemical Recurrence in Patients Submitted to Radical Prostatectomy Under General Opioid-free Anesthesia Compared to Conventional General Anesthesia
The use of opioids facilitates angiogenesis and has a proven action in the immune system, mainly in the reduction of natural killer cell activity, favoring the migration of neoplastic cells and inhibiting humoral and cellular…
- Trial name
- NCT03212456
- Testing
- opioid-free group, Opioid Group, transversus abdominal plane block with ropivacaine
- Where
- Brazil
- Volunteers
- 146 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Parkinson's Disease
Therapeutic Yoga to Improve Function in Parkinson's Disease
This is a single blind, randomized, wait-list controlled, phase II exploratory pilot study.
- Trial name
- NCT02902510
- Testing
- Therapeutic yoga for people with Parkinson's Disease
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clemson University
Physiological Parameters
Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients
The study aims to determine the effect of implementing cough augmentation techniques on weaning outcomes among critically ill patients
- Trial name
- NCT07722260
- Testing
- cough augmentation techniques
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Heba.Attia@nur.dmu.edu.eg
Community-dwelling Older Adults
Effect of Personalised Citizen Assistance for Social Participation(APIC) on Older Adults Health and Social Participation
Global aging and the growing burden of chronic diseases represent a challenge. Innovative interventions acting upon health determinants, like social participation, are required.
- Trial name
- APIC (NCT03161860)
- Testing
- Personalised citizen assistance for social participation(APIC)
- Where
- 6 sites in Canada
- Volunteers
- 180 people
- Sponsor
- Mélanie Levasseur
Tooth Movement Techniques
Effect of Implant Driver Facilitated Micro-osteo Perforation on the Rate of Tooth Movement.
we have conducted a split-mouth randomized clinical trial to study effects of implant induced micro-osteoperforations on the rate of tooth movement during canine retraction.
- Trial name
- NCT05339620
- Testing
- implant driver facilitated micro-osteoperforations
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Bahria University
Scleral Buckling
The Effect of Glaucoma Drops on of the Duration of a Pure Intraocular Gas Bubble
A controlled clinical study comparing the effect of topical aqueous suppressants on intraocular gas duration.
- Trial name
- NCT01843920
- Testing
- Timolol-dorzolamide (Glaucoma drops), standard post-operative topical drops
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Jason Hsu, MD
Eye Movement
Development and Validation of a Novel Eye-Tracking Software-based Platform to Extract Oculometric Measures
This is an observational prospective study in a cohort of healthy subjects who are enrolled using convenience and snowballing sampling.
- Trial name
- NCT05476523
- Testing
- NeuraLight
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- NeuraLight
Healthy Adult Participants, Acute Stress Reaction
Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test
This study investigates whether the psychophysiological benefits of breathing exercises are driven by a specific physiological rhythm (6 breaths per minute) or by the general psychological experience of performing a structured…
- Conditions
- Healthy Adult Participants, Acute Stress Reaction, Stress Biomarkers, Healthy
- Trial name
- NCT07529379
- Testing
- Coherent Breathing (6 bpm)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Meniscectomy, Osteoarthritis
Verifying the Effectiveness of the NUsurface® System
The NUsurface® Meniscus Implant Randomized Study is a multi-center, prospective randomized, interventional clinical trial to test the hypothesis that the NUsurface implant is superior to the non-surgical standard of care in…
- Trial name
- VENUS (NCT02108496)
- Testing
- NUsurface® Meniscus Implant, NSAID's and Non-surgical Treatment Options, Intra-Articular Injections with Corticosteroids
- Where
- 9 sites in United States
- Volunteers
- 337 people
- Sponsor
- Phoenix Kinetics
COVID-19
Study to Evaluate the inHaled Recombinant COVID-19 Vaccine (Adenovirus Type 5 Vector) On the Protective-Efficacy in Adults (SeiHOPE)
This phase III clinical trial is an endpoint-driven randomized, double-blind, parallel-controlled, multicenter clinical trial, and around 13,000 subjects aged 18 years and above who have previously received 1 dose of…
- Trial name
- NCT05124561
- Testing
- Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH)
- Volunteers
- healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Liver Fibrosis
Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Viral Hepatitis B Phase 3 Trial.
This study was a randomized, double-blind, placebo-controlled, entecavir basic treatment, multicentre clinical study. The main objective of this study was to confirm the efficacy and safety of hydronidone in the treatment of…
- Trial name
- NCT05115942
- Testing
- Hydronidone capsules
- Where
- 44 sites in China
- Volunteers
- 248 people
- Sponsor
- Beijing Continent Pharmaceutical Co, Ltd.
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