Clinical trials: Experimental Group
Osteoporosis, Postmenopausal
Efficacy of OsteoBor in Postmenopausal Osteoporosis
This study aims to evaluate the impact of boron supplementation (OsteoBor) on bone health in postmenopausal women. The trial is a phase 2, randomised, double-blind, placebo-controlled study lasting one year
- Trial name
- NCT06809816
- Testing
- Sodium pentaborate pentahydrate
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tabriz University of Medical Sciences
Lung Surgery
Evaluation of the Effectiveness and Security of TenaTac® in the Prevention of Air Leaks in Thoracic Surgery
Lung surgery remains a high-risk procedure, with serious adverse events that can occur later, including postoperative bleeding or hemothorax, pneumopathy or surgical site infection but also ... per- and post-operative air leaks.
- Trial name
- TENATAC (NCT06597604)
- Testing
- Intraoperative use of TenaTac in lung surgery, Intraoperative use of usual sealant in lung surgery
- Where
- 2 sites in France
- Volunteers
- 154 people
- Sponsor
- Hopitaux Prives de Metz, Groupe UNEOS
Diabetes, Type 2 Diabetes
Effect of Sensory Training on Functional Performance, Balance, Gait in Type 2 Diabetic Individuals With Neuropathy
Diabetic peripheral neuropathy (DPN) is a common complication of type 1 and type 2 diabetes. DPN is characterized by significant axonal degeneration and segmental demyelination affecting sensory and motor nerves.
- Conditions
- Diabetes, Type 2 Diabetes, Diabetic Peripheral Neuropathy, Kinesiophobia
- Trial name
- NCT06979401
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Aylin DEMİR
Heart Failure
BioTechCOACH-ForALL: Development of Mental and Physical Exercise Systems, Clinical Recording, Supervisory Analytical Large-scale Data and Virtual Guidance of Vulnerable Population Groups
This would be a single center, parallel, two group randomized controlled pilot study that is designed to assess the feasibility and efficacy of the Virtual Coach Program in elderly patients with heart failure.
- Trial name
- NCT03877328
- Testing
- BiotechCoachForAll
- Where
- 2 sites in Greece
- Volunteers
- 13 people
- Sponsor
- Aristotle University Of Thessaloniki
Fibromyalgia
Effectiveness of an IVR-based Therapeutic Exercise Program With Altered Visual Feedback in Fibromyalgia Patients
The primary aim of this randomized controlled trial is to determine the efficacy of a 6-week immersive virtual reality (IVR)-based therapeutic exercise intervention, which manipulates visual proprioceptive input during exercise…
- Trial name
- IVR-F (NCT06948500)
- Testing
- Immersive Virtual Reality, Physical Activity
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Cardenal Herrera University
Chewing Problem, Cognitive Decline
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study
Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia.
- Conditions
- Chewing Problem, Cognitive Decline, Magnetic Resonance Imaging, Degenerative; Dementia
- Trial name
- NCT04458207
- Testing
- Oral prosthetic rehabilitation
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Folktandvården Stockholms län AB
Anxiety, Depression
Contextual Therapies and Cognitive Behavioral Therapy as Transdiagnostic Group Interventions for Emotional Disorders
This study aims to investigate the efficacy of three psychotherapeutic programs in group format: Acceptance and Commitment Therapy (ACT), Behavioral Activation (AC) and Transdiagnostic Cognitive Behavioral Therapy (TD-CBT), for…
- Trial name
- TRANSACTIVA (NCT04117464)
- Testing
- Behavioral activation therapy, Acceptance and Commitment Therapy, Cognitive-Behavioral Therapy
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- University of Oviedo
Spasticity as Sequela of Stroke
EXOPULSE Mollii Suit, Motor Function & Stroke (EXOSTROKE)
Spasticity is a common and debilitating complication in neurological conditions such as multiple sclerosis, cerebral palsy, and stroke.
- Trial name
- EXOSTROKE (NCT06702163)
- Testing
- EXOPULSE MOLLII SUIT (active)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Chronic Renal Failure With Hemodialysis
Study of rESP Injection for the Treatment of Anemia in Chronic Renal Failure Patients With Hemodialysis
A phase 2, randomized, open label, active comparator parallel controlled study to explore the dosage regiment of rESP, and evaluate its efficacy, safety and pharmacokinetic characteristics in the treatment of anemia in chronic…
- Trial name
- NCT03950687
- Testing
- Recombinant Human Erythropoiesis Injection (CHO cell), Recombinant Erythropoiesis Stimulating Protein Injection(CHO cell)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Obesity, Metabolic Disease
Thermogenic Silencer Regulatory Factors in Humans
A promising approach to correct the metabolic dysfunction associated with obesity is to activate brown fat non-shivering thermogenesis (NST).
- Conditions
- Obesity, Metabolic Disease, Cold Exposure
- Trial name
- NCT06424132
- Testing
- Cold Vest Exposure Period, Rewarming Exposure Period, Fasting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Colorectal Cancer
Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer
This is a multi-center, single-arm study to investigate the efficacy and safety of liposomal irinotecan+5-FU/LV+ bevacizumab as second-line therapy in metastatic colorectal cancer in Chinese population.
- Trial name
- NCT06184698
- Testing
- liposomal irinotecan, 5-FU, LV
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Hebei Medical University Fourth Hospital
Chronic Migraine
Effectiveness of a Health Education Programme for Prevention of Chronic Migraine: A Randomized Clinical Trial
Chronic migraine (CM) is a common and frequent disorder, which has a major impact on the quality of life of migraine sufferers, interfering with physical function, productivity at work, personal life and leisure, lifestyle and…
- Trial name
- NCT04788667
- Testing
- A health education programme using a telerehabilitation platform
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Universidad de Zaragoza
mHealth, Mindfulness
The Effectiveness of a Mindfulness Application on Perceived Stess
Mindfulness has become increasingly popular and positive outcomes have been reported for mindfulness-based interventions (MBIs) in reducing stress.
- Conditions
- mHealth, Mindfulness, Stress, Burnout
- Trial name
- NCT05246800
- Testing
- Structured 8-week mHealth mindfulness program
- Where
- Netherlands
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Post-COVID-19 Syndrome
Cognitive Rehabilitation in Post-COVID-19 Syndrome
The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS).
- Trial name
- NCT06136871
- Testing
- CO-OP Procedures, Inactive Control Group
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Missouri-Columbia
Advanced and Metastatic Solid Tumor
Regorafenib and Nivolumab Simultaneous Combination Therapy
the efficacy and safety ofhe use of regorafenib in combination with nivolumab
- Trial name
- REGONIVO (NCT03406871)
- Testing
- Regorafenib, Nivolumab
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Kohei Shitara
HIV
Barbershop Talk: HIV Prevention for African American Heterosexual Men
This program utilizes a community-engaged research approach to implementing and evaluating a program that seeks to reduce sexual risk behavior among Black adult heterosexual men.
- Trial name
- NCT01980771
- Testing
- BTWB intervention, Cancer prevention and screening
- Where
- 2 sites in United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- State University of New York - Downstate Medical Center
Chronic Non-specific Neck Pain, Neck Pain
Effect of Cervical Force Control Training on Force Sense and Steadiness in Chronic Non-Specific Neck Pain
Chronic non-specific neck pain (CNSNP) is a very common issue among young adults, often linked to poor posture, prolonged screen time, and sedentary habits.
- Trial name
- NCT07813871
- Testing
- Cervical Force Control Training, Conventional Exercise Training
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Infant, Newborn, Infant, Low Birth Weight
The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants
This study tested the safety and efficacy of transfusing erythropoietin (Epo) and iron in infants of <1,250g birth weight. For infants 401-1,000g birth weight, we tested whether early erythropoietin (Epo) and iron therapy would…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- EPO (NCT01203514)
- Testing
- Erythropoietin
- Where
- 9 sites in United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Parkinson Disease (PD), Immersive Virtual Reality
Virtual Reality on Balance of Parkinson's Disease
This study, titled: Effectiveness of immersive virtual reality on balance in people with Parkinson's disease. Is a randomized clinical trial conducted at Zaragoza Parkinson's Association in Spain.
- Conditions
- Parkinson Disease (PD), Immersive Virtual Reality, Physical Therapy
- Trial name
- RVI-PD (NCT07274514)
- Testing
- Immersive Virtual Reality Program, Standard Rehabilitation Program
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Depression, Sleep Quality
Effect of Music Activities on Depression and Sleep Quality in Frail Older Adults
This study aims to examine the effects of music activities on depression and sleep quality among frail older adults, and to develop a standardized music activity protocol suitable for use in adult day care centers.
- Conditions
- Depression, Sleep Quality, Frailty
- Trial name
- NCT07049445
- Testing
- Music Activity Program
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
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