Clinical trials: Hydrocortisone, completed
Cushing's Syndrome
An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Participants in study C-1073-400 (NCT00569582) will be invited to participate in this extension study to examine the long term safety of mifepristone in the treatment of the signs and symptoms of endogenous Cushing's syndrome.
- Trial name
- NCT00936741
- Testing
- mifepristone
- Where
- 15 sites in United States
- Volunteers
- 30 people
- Sponsor
- Corcept Therapeutics
Advanced Malignant Neoplasm, Dermatologic Complication
Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab
This randomized phase II trial studies how well giving spironolactone works in preventing rash in patients with cancer that has spread to other places in the body and are receiving panitumumab and cetuximab.
- Trial name
- NCT01867294
- Testing
- Doxycycline, Management of Therapy Complications, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Academic and Community Cancer Research United
Alopecia Areata
A Trial of Clobetasol Propionate Versus Hydrocortisone in Children With Alopecia Areata
The use of topical steroids in the treatment of alopecia areata in children is common practice. However, no particular potency of steroid is accepted as the standard treatment due to the paucity of high quality evidence in the…
- Trial name
- NCT01453686
- Testing
- Hydrocortisone 1%, Clobetasol Propionate 0.05%
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- The Hospital for Sick Children
Chronic Stress
The Effects of Dietary Factors on Physiological Subjective Stress Responses
The study aims to investigate the role of dietary factors in chronically stressed subjects. Previous studies have shown that milk proteins, B vitamins and probiotics may influence on subjective well-being in stressed subjects.
- Trial name
- AivoPro2 (NCT01544270)
- Testing
- Yogurt-like snacks
- Where
- Finland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Interleukin-6, Cortisol
Effectivity of Bilateral Transversus Thoracis Muscle Plane Block After Open Heart Surgery
This Study aimed to assess The Effectivity of Bilateral Transversus Thoracis Muscle Plane Block to Reduce Pain and Stress Response After Open Heart Surgery
- Trial name
- NCT04544254
- Testing
- Bilateral transversus thoracis muscle plane block, Control
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Adrenal Insufficiency
Hydrocortisone Replacement in Patients With Secondary Adrenal Insufficiency (SUPREME CORT)
The aim of this study is to investigate whether a physiologically low hydrocortisone (HC) dose is better for cognition as compared to a physiologically high HC dose.
- Trial name
- SUPREME CORT (NCT01546922)
- Testing
- Hydrocortisone
- Where
- Netherlands
- Volunteers
- 63 people
- Sponsor
- University Medical Center Groningen
Seborrheic Dermatitis
Topical Terbinafine Versus Hydrocortisone Combined With Oral Itraconazole for Seborrheic Dermatitis
The goal of this clinical trial is to compare two creams used together with oral itraconazole in adults with moderate-to-severe seborrheic dermatitis.
- Trial name
- NCT07906886
- Testing
- Itraconazole, Terbinafine 1% cream, Hydrocortisone 1% cream
- Where
- 2 sites in Vietnam
- Volunteers
- 76 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Psoriasis Vulgaris
Vasoconstriction Trial With LEO 90100 Aerosol Foam
Vasoconstriction study with LEO 90100
- Trial name
- NCT02973776
- Testing
- LEO 90100 aerosol foam, Dermoval®/Dermovate®, Diprosone
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Sepsis, Septic Shock
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
Prospective, experimental, longitudinal cohort study in septic patients treated at ER and ICU at General Hospital Zone 11 IMSS Piedras Negras Coahuila.
- Trial name
- NCT04197115
- Testing
- Vitamin C, Hydrocortisone, Complex B
- Where
- Mexico
- Volunteers
- 19 people
- Sponsor
- IMSS Hospital General de Zona 11, Piedras Negras
Yohimbine, Hydrocortisone
The Role of Stress Neuromodulators in Decision Making Under Risk and Selective Attention to Threat
Incidental affective states, i.e., affective states can influence decision making and selective attention to threatening information.
- Conditions
- Yohimbine, Hydrocortisone, Yohimbine + Hydrocortisone, Placebo
- Trial name
- SID (NCT04359147)
- Testing
- "Yohimbine", "Hydrocortisone", "Yohimbine + Hydrocortisone"
- Where
- Germany
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Training Group, Sensitivity
The Application of Microcurrent in Athletes
The aim of this investigation is to analyse the potential benefits of wearing a new commercially available microcurrent device combined with different exercise training modalities on exercise outcomes, body composition, recovery…
- Trial name
- NCT03477747
- Testing
- Microcurrent
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Depression
Depression, Adversity, and Stress Hormones (DASH) Study
The stress-related hormone cortisol has been studied in depression for decades. However, relatively little is known about the role of cortisol in psychological features of depression.
- Trial name
- DASH (NCT03195933)
- Testing
- Cortisol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Multiple Sclerosis
Physical Therapy and Neuroactive Steroids Therapy Does Not Modulate Serum Level of Neuroactive Steroids
This study describes modulation of neuroproprioceptive facilitation and inhibition physical therapy on serum level of neuroactive steroids in multiple sclerosis.
- Trial name
- NCT04379193
- Testing
- Neuroproprioceptive facilitation and inhibition physical therapy
- Volunteers
- 63 people
- Sponsor
- Charles University, Czech Republic
Adrenocortical Carcinoma
Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)
This study will investigate the safety and efficacy of Relacorilant in combination with Pembrolizumab for Patients with Adrenocortical Carcinoma which Produces Too Much Stress Hormone (Cortisol).
- Trial name
- NCT04373265
- Testing
- Relacorilant, Pembrolizumab
- Where
- 6 sites in United States
- Volunteers
- 15 people
- Sponsor
- Corcept Therapeutics
Cannabis Use, Cannabis
Investigating Real-world Stress-related Mechanisms in Heavy Cannabis Users
This research project proposes a novel approach to elucidate the biological adaptations associated with heavy cannabis use and to assess whether such adaptations are predictive of higher cannabis craving in response to both…
- Conditions
- Cannabis Use, Cannabis, Cannabis Abuse
- Trial name
- CLR2 (NCT05833230)
- Testing
- Intensive Day Monitoring
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yale University
Congenital Adrenal Hyperplasia, Adrenal Insufficiency
An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone
This was an open label, randomized, single dose, three period crossover pharmacokinetic study of Chronocort® in 30 healthy male volunteers. The study was conducted in smaller sub groups (Group 1, n=18 and Group 2, n=12).
- Trial name
- NCT03019614
- Testing
- Hydrocortisone, Chronocort
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neurocrine UK Limited
Diabetes Mellitus, Wound Healing Delayed
Effect of Hyaluronic Acid and Single Dose Corticosteroid Injection to Improve Wound Healing in Controlled Diabetic Patients Post Tooth Extraction.
The goal of this clinical trial is to learn if hyaluronic acid and corticosteroid improves wound healing in diabetic patients after oral extraction.
- Trial name
- NCT06637384
- Testing
- Hyaluronic Acid (HA), Corticosteroid Injection
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Rimsha Rasheed
Dental Implant
Immediate Implants: to Graft or Not to Graft, That is the Question.
The aim was to compare two protocols for immediate implants with fixed provisional restoration, no grafting (trimodal approach=TA) versus grafting both osseous gap and peri-implant mucosa (trimodal approach with modification of…
- Trial name
- TAOM-TA (NCT05927181)
- Testing
- TAOM
- Where
- Spain
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Sleep Disorder
Associations of Socioeconomic Adversity and Sleep With Allostatic Load Among Toddlers
A longitudinal study to examine the relationships among sleep characteristics, stress, and child behavior problems in a community sample of toddlers (12-24 months- ages 12-15 months at enrollment) living in socioeconomically…
- Trial name
- NCT03419871
- Testing
- Monitoring Sleep, stress biomarkers
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Sepsis
Cortisol Control of Human Inflammatory Responses to Endotoxin
The purpose of the research is to study a common and dangerous medical condition called 'septic shock' that often occurs in critically ill patients.
- Trial name
- NCT00396344
- Testing
- Çontrol, Hydrocortisone
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center